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Cord Blood Stem Cells Increased Tenfold

September 29, 2014 | by Cynthia Fox | Comments

Ten times more stem cells may soon be generated from umbilical cords than ever before, according to a new Science study. The potential advance was made via a little-known pyrimidoindole molecule called UM171.

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Nobel Prize-winning ‘iPSC’ Stem Cell Method Vastly Improved

September 25, 2014 8:30 am | by Cynthia Fox | Comments

By adding just three compounds to the Nobel Prize-winning induced pluripotent stem cell recipe, a research group is reporting a huge 90 to 100 percent stem cell haul in under a week.                  

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Two Anti-Ebola Vaccines in Historic Race

September 11, 2014 3:38 pm | by Cynthia Fox | Comments

One of the most rapidly fast-tracked vaccines in history— an anti-Ebola “ChAd3” vaccine— just started clinical trial in humans, and may be done as soon as November. But a second fast-tracked anti-Ebola vaccine— called an “rVSV” vaccine— is hot on its heels.

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ZMapp: Best Anti-Ebola Treatment Yet

September 4, 2014 3:05 pm | by Cynthia Fox | Comments

ZMapp, an experimental drug that may have already have saved a few patients in Africa, is the most effective anti-Ebola therapy yet, according to a recent Nature paper on rhesus macaques monkeys.              

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Prominent Japan Stem Cell Center to Undergo Changes

September 2, 2014 3:55 pm | by Cynthia Fox | Comments

Riken Center for Developmental Biology (CDB), the prominent Japan institute where Haruko Obokata was found to commit misconduct on stem cell papers, will be halved, according to a Riken representative.              

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Making Bones from Beer Waste

August 28, 2014 8:30 am | by Skip Derra | Comments

At first blush it is a bit disingenuous, using beer waste as a base material for new bone. But that is exactly what a multidisciplinary team of researchers in Spain has come up with in a process for making the substrate material on which bone can be regenerated.

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Amid ALS Mania, Possible Drug Target Spotted

August 26, 2014 11:41 am | by Cynthia Fox | Comments

As, all around them, everyone from Derek Jeter to the Kennedy family was dousing themselves in ice water for the ALS “Ice Bucket Challenge,” Harvard researchers announced last week they may have found an ALS therapy— or two.       

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Exercise Can Impact Breast Cancer Risk

August 25, 2014 3:38 pm | by Cynthia Fox | Comments

A large new study found that when post-menopausal women stop physical activity, their odds of developing breast cancer rise. But, the study also found that breast cancer risk drops surprisingly rapidly after exercise starts.                  

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‘The Pill’ Shrinks Ovaries, Cuts Egg Numbers

August 21, 2014 2:44 pm | by Cynthia Fox | Comments

The birth control pill significantly affects ovarian reserve— or the number of immature eggs in a woman’s ovaries— which can be a predictor of future fertility, according to a team in Denmark.                 

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Cloning Offers Intriguing Stem Cell-Making Tips

July 28, 2014 10:36 am | by Cynthia Fox | Comments

Two recent studies— one human, one mouse— have found cloning creates better pluripotent stem cells than the Nobel Prize-winning induced pluripotent stem cell (iPSC) method. A third study also came out supporting the conclusions.     

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Long-Awaited, Global Trial of Fetal Cells for Parkinson’s

July 21, 2014 2:45 pm | by Cynthia Fox | Comments

In two months, the first of many new Parkinson’s disease (PD) patients will receive a fetal cell transplant. The transplant will mark the end of a voluntary moratorium by many Western nations after complications arose a decade ago. This, combined with news that embryonic stem (ES) cell PD therapies may also near prime-time, made Parkinson’s a big topic at the recent International Society for Stem Cell Research (ISSCR) meeting.

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ISSCR: Promising Stem Cell Clinical Trials

July 17, 2014 1:22 pm | by Bioscience Technology Staff | Comments

Many promising clinical trials were highlighted at the annual meeting of the International Society of Stem Cell Research (ISSCR). One set of trials highlighted were monogenic gene therapy trials and cancer immunotherapy trials. Also discussed were trials for Parkinson’s disease, Multiple Sclerosis, and potential future trials involving cochlear stem cells.

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One for the Aged

July 15, 2014 2:32 pm | by Skip Derra | Comments

What we currently know about aging is not highly specific; our cells divide many times throughout our lives and eventually cause organs and our bodies to age, break down and fail. New research, however, suggests that how we age might depend on cellular interactions that we inherit from our ancestors, accumulating throughout many generations.

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As STAP Papers are Retracted, A Riken Researcher Mulls Stalling World-First Trial

July 2, 2014 2:55 pm | by Cynthia Fox | Comments

Just as Nature was setting about retracting two famous Riken CDB papers claiming to make “STAP” stem cells from ordinary cells, another Riken researcher said she might suspend a world-first clinical trial of a competing—legitimate—stem cell technique. But within hours, she modified her views, according to Riken.

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Stem Cells Halt MS for Two Years

July 1, 2014 12:07 pm | by Cynthia Fox | Comments

At 21, MS had Jennifer Molson “wheelchair bound.” But since her stem cell transplant, she has worked, driven, danced at her own wedding. The story had a room of 1,000 professional stem cell scientists sniffling loudly at the International Society for Stem Cell Research (ISSCR) meeting—said sniffling reaching a crescendo when the quiet, pretty Molson concluded: “I’m living proof stem cells can save lives.”

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One Japan Stem Cell Institute Soars, One Struggles

June 18, 2014 12:59 pm | by Cynthia Fox | Comments

As Nobel Prize-winning scientist Shinya Yamanaka regaled a New York crowd with advances that may send his Japanese institute to the top of the global stem cell field, investigators in Tokyo said the stem cell division at his sister institute is so wracked with problems it should dismantle—or dramatically revamp.

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