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The Lead

Brain Scans Help Tailor Alcoholism Treatment

November 25, 2014 2:38 pm | News | Comments

Clinical research is using brain imaging and drug therapy to better understand how microscopic changes in brain connectivity relate to alcohol dependence and recovery.                        

New Device Could Make Large Biological Circuits Practical

November 25, 2014 2:20 pm | News | Comments

A team of researchers has come up with a way of greatly reducing the unpredictability of...

Creating Pain-sensing Neurons

November 25, 2014 2:11 pm | News | Comments

After more than six years of intensive effort, including repeated failures that at times...

Brain Protein Linked to Sleep May be Alzheimer’s Prevention Target

November 25, 2014 2:02 pm | News | Comments

A protein that stimulates the brain to awaken from sleep may be a target for preventing...

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New FDA Rules Will Put Calorie Counts on Menus

November 25, 2014 1:00 pm | by Mary Clare Jalonick - Associated Press - Associated Press | News | Comments

Whether they want to or not, consumers will soon know how many calories they are eating when ordering off the menu at chain restaurants, picking up prepared foods at supermarkets and even eating a tub of popcorn at the movie theater.     

Salmonella in 10 States Linked to Raw Sprouts

November 24, 2014 2:58 pm | by Mary Clare Jalonick - Associated Press - Associated Press | News | Comments

Raw sprouts are linked to dozens of cases of food poisoning - again. The CDC said 63 people from 10 states concentrated on the East Coast fell ill with salmonella linked to bean sprouts.                   

Merck, Iowa Firm Sign Ebola Vaccine Licensing Deal

November 24, 2014 1:58 pm | by Linda A. Johnson - AP Business Writer - Associated Press | News | Comments

Merck & Co., a top creator and seller of vaccines, has joined the fight against Ebola, the often-fatal hemorrhagic virus that's been ravaging parts of West Africa for months.                     

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Exciting Gains in Fighting Breast Cancer Hormone-therapy Resistance

November 24, 2014 1:56 pm | by Cynthia Fox, Science Writer | Articles | Comments

Guided by breakthrough research on the Estrogen Receptor 1 (ESR1) gene, many researchers and pharmaceutical companies are in hot pursuit of the next big anti-resistance breast cancer drug.                  

Computer Games Could Prevent Falls in the Elderly

November 24, 2014 12:22 pm | News | Comments

A research team has developed new computer games designed to significantly reduce the likelihood of falls at home and in the community among older people.                            

Test Detects Early Brain Damage in Football Players

November 24, 2014 12:12 pm | News | Comments

A new, enhanced MRI diagnostic approach was, for the first time, able to identify significant damage to the blood-brain barrier (BBB) of professional football players following “unreported” trauma or mild concussions.          

Tiny Patient Prompts Advance in Neurogenetics

November 24, 2014 11:54 am | News | Comments

Researchers had never shown exactly how cells in the brain stem detect carbon dioxide and regulate breathing in humans. After taking a mutation from a two-month-old baby and expressing it in human astrocytes, they did exactly that, and the research may lead to an early warning system to save premature infants.

Schizophrenia May be Triggered by Excess Protein

November 24, 2014 11:18 am | News | Comments

A gene associated with schizophrenia plays a role in brain development and may help to explain the biological process of the disease, according to new research.                          

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U.S. Looking Past Ebola to Prepare for Next Outbreak

November 23, 2014 8:57 am | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

The next Ebola or the next SARS. Maybe even the next HIV. Even before the Ebola epidemic in West Africa is brought under control, public health officials are girding for the next health disaster.               

Plague Outbreak Kills 40 in Madagascar

November 22, 2014 5:57 am | by Lynsey Chutel - Associated Press - Associated Press | News | Comments

A plague outbreak has killed 40 people on the island nation of Madagascar, with 119 people diagnosed with the bacterial disease since August. Two people have been diagnosed and one has died in the capital, Antananarivo.        

Bee Brains Offer Insights Into How Human Memories Form

November 21, 2014 10:28 am | News | Comments

University of Queensland scientists have discovered that genes switch off as memories are being formed, allowing for new connections between nerve cells. Read more...                                       

Researchers Find How Mutant Gene Can Cause Deafness

November 21, 2014 10:12 am | News | Comments

Scientists at The Scripps Research Institute (TSRI) have discovered how one gene is essential to hearing, uncovering a cause of deafness and suggesting new avenues for therapies. Read more...                                       

Researchers Tease Out Glitches in Immune System's Self-Recognition

November 21, 2014 10:06 am | News | Comments

Immunity is a thankless job. Though the army of cells known as the immune system continuously keeps us safe from a barrage of viruses, bacteria and even precancerous cells, we mainly notice it when something goes wrong: “Why did I get the flu this year even though I got vaccinated?” Read more...

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Cellular Origin of Fibrosis

November 21, 2014 10:00 am | News | Comments

Harvard Stem Cell Institute scientists at Brigham and Women’s Hospital say they have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions. Read more...

Unwinding the Mysteries of the Cellular Clock

November 21, 2014 9:54 am | News | Comments

Human existence is basically circadian. Most of us wake in the morning, sleep in the evening, and eat in between. Body temperature, metabolism, and hormone levels all fluctuate throughout the day, and it is increasingly clear that disruption of those cycles can lead to metabolic disease. Read more...

Study: Obesity Fuels Silent Heart Damage

November 21, 2014 9:27 am | News | Comments

Using an ultrasensitive blood test to detect the presence of a protein that heralds heart muscle injury, researchers from Johns Hopkins and elsewhere have found that obese people without overt heart disease experience silent cardiac damage that fuels their risk for heart failure down the road. Read more...      

Damage to Brain Networks Affects Stroke Recovery

November 21, 2014 9:21 am | News | Comments

Initial results of an innovative study may significantly change how some patients are evaluated after a stroke, according to researchers at Washington University School of Medicine in St. Louis. Read more...                  

3-D-Printed Model Helps Treat Patients with Heart Disorders

November 20, 2014 10:43 am | News | Comments

An experimental 3-dimensional printed model of the heart may help surgeons treat patients born with complicated heart disorders, according to new research.                           

Gene Therapy Pioneered to Cure 'Bubble Baby' Disease

November 20, 2014 10:35 am | Videos | Comments

Researchers have pioneered a stem cell gene therapy cure for children born with adenosine deaminase (ADA)-deficient severe combined immunodeficiency (SCID), often called "Bubble Baby" disease.                 

How Mosquitoes Home In

November 20, 2014 10:27 am | News | Comments

They have been a scourge for thousands of years, responsible for the spread of lethal diseases such as malaria and dengue fever, and, much less urgently, a threat to barbecues around the globe. What if there was a way to render humans invisible to mosquitoes?

Exploring the Genomes of Mice and Men

November 20, 2014 10:15 am | News | Comments

For decades, the mouse has been a mainstay for researchers studying human diseases because the two species share many of the same genes. But now, a comprehensive analysis of the inner workings of the DNA in humans and mice has uncovered some striking differences in the way their genes are controlled.

WHO: Ebola Transmission 'Intense' in Sierra Leone

November 20, 2014 5:57 am | by Clarence Roy-Macaulay – Associated Press – Associated Press | News | Comments

The spread of Ebola remains "intense" in most of Sierra Leone even as things have improved somewhat in the two other countries hardest hit, the World Health Organization says.                     

Surrogate Sushi: Japan Biotech for Bluefin Tuna

November 20, 2014 2:57 am | by Elaine Kurtenbach - AP Business Writer - Associated Press | News | Comments

Of all the overfished fish in the seas, luscious, fatty bluefin tuna are among the most threatened. Marine scientist Goro Yamazaki, who is known in this seaside community as "Young Mr. Fish," is working to ensure the species survives.     

Early Statin Use May Give Long-term Heart Benefits

November 19, 2014 2:57 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

Research shows that taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward. The benefits seem to grow over time and may last for life.               

Mental Health Problems Increase Cardiovascular Disease Risk

November 19, 2014 2:18 pm | by Cynthia Fox, Science Writer | Articles | Comments

People with mental health problems are “significantly” more likely to have stroke or heart disease, according to a study unveiled at a recent Canadian Cardiovascular Congress.                    

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