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The Lead

Only 8.2% of DNA is ‘Functional’

July 24, 2014 2:45 pm | News | Comments

Only 8.2 percent of human DNA is likely to be doing something important – is “functional”– say researchers. This figure is very different from one given in 2012, when some scientists stated that 80 percent of our genome has some biochemical function.

Dyes Used to Paint New Picture of Disease

July 24, 2014 2:12 pm | News | Comments

By using brightly hued dyes, George Mason University (GMU) researchers discovered an innovative...

Background TV Can be Bad for Kids

July 24, 2014 1:24 pm | Videos | Comments

Parents, turn off the television when your children are with you. And when you do let them watch...

Researchers Show How Stress Hormones Promote Building of Negative Memories

July 24, 2014 1:16 pm | News | Comments

When a person experiences a devastating loss or tragic event, why does every detail seem burned...

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China Lifts Quarantine in Plague City

July 24, 2014 1:20 am | News | Comments

A nine-day quarantine imposed on parts of a northern Chinese city where a man there died of bubonic plague has been lifted, China's official news agency reported Thursday.                       

Head of Troubled CDC Anthrax Lab Resigns

July 23, 2014 1:20 pm | by The Associated Press | News | Comments

Health officials say that the head of the government lab which potentially exposed workers to live anthrax has resigned. Michael Farrell was head of the Centers for Disease Control and Prevention lab since 2009.            

Try, Try Again? Study Says No

July 23, 2014 11:00 am | News | Comments

In a new study, a team of researchers has found evidence for a factor that contributes to adults’ language difficulties: When learning certain elements of language, adults’ more highly developed cognitive skills actually get in the way.     

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Human Platelets Generated in Bioreactor

July 23, 2014 10:47 am | News | Comments

Scientists have developed a scalable, next-generation platelet bioreactor to generate fully functional human platelets in vitro. The work might help address blood transfusion needs worldwide.                  

Researchers ID Mechanism to Clear Diabetes-related Pancreatic Protein

July 23, 2014 10:43 am | News | Comments

People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells. Now, a team of researchers may have found a solution in autophagy, a process that clears damaged and toxic proteins from cell.

Mapping Finds New Schizophrenia-linked Genes

July 23, 2014 8:30 am | by Seth Borenstein - AP Science Writer - Associated Press | News | Comments

Scientists have linked more than 100 spots in our DNA to the risk of developing schizophrenia, casting light on the mystery of what makes the disease tick. Such work could eventually point to new treatments, although they are many years away.   

Stem Cells Aid Muscle Repair and Strengthening After Resistance Exercise

July 22, 2014 2:10 pm | News | Comments

A new study in mice reveals that mesenchymal stem cells (MSCs) help rejuvenate skeletal muscle after resistance exercise. By injecting MSCs into mouse leg muscles prior to several bouts of eccentric exercise, researchers were able to increase the rate of repair and enhance the growth and strength of those muscles in the exercising mice.

Researchers Successfully Eliminate the HIV Virus from Cultured Human Cells

July 22, 2014 1:49 pm | Videos | Comments

The HIV-1 virus has proved to be tenacious, inserting its genome permanently into its victims' DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.

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Mixed Genes Mix Up the Migrations of Hybrid Birds

July 22, 2014 1:23 pm | News | Comments

Mixed genes appear to drive hybrid birds to select more difficult routes than their parent species, according to new research from University of British Columbia zoologists. the researchers harnessed a flock of B.C. Swainson’s thrushes with tiny geolocating backpacks to map their routes as they migrated south through the U.S. to Central and South America.

Breaking News: Lack of Vitamin D Ups Schizophrenia Risk

July 22, 2014 1:17 pm | News | Comments

Vitamin D-deficient individuals are twice as likely to be diagnosed with schizophrenia as people who have sufficient levels of the vitamin, according to a new study.                        

Long-Awaited, Global Trial of Fetal Cells for Parkinson’s

July 21, 2014 2:45 pm | by Cynthia Fox | Articles | Comments

In two months, the first of many new Parkinson’s disease (PD) patients will receive a fetal cell transplant. The transplant will mark the end of a voluntary moratorium by many Western nations after complications arose a decade ago. This, combined with news that embryonic stem (ES) cell PD therapies may also near prime-time, made Parkinson’s a big topic at the recent International Society for Stem Cell Research (ISSCR) meeting.

Metabolic Enzyme Stops Progression of Kidney Cancer

July 21, 2014 1:52 pm | News | Comments

In an analysis of metabolites used by the body to make fuel in normal and cancerous cells in human kidney tissue, a research team identified an enzyme that is key to applying the brakes on tumor growth.              

New Technique Maps Life's Effects on Our DNA

July 21, 2014 1:39 pm | News | Comments

Researchers have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents. The technique can be used to map all of the 'epigenetic marks' on the DNA within a single cell.

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New Trigger for Ovulation Could Make IVF Safer

July 21, 2014 12:34 pm | Videos | Comments

Researchers have successfully used a new and potentially safer method to stimulate ovulation in women undergoing IVF treatment. Twelve babies have been born after their mothers were given an injection of the natural hormone kisspeptin to make their eggs mature.

Common Gene Variants Account for Most Genetic Risk for Autism

July 21, 2014 11:26 am | News | Comments

Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches, researchers have found. Heritability also outweighed other risk factors in this largest study of its kind to date.

New Findings Show Early Seeding of HIV Viral Reservoir

July 21, 2014 11:13 am | News | Comments

A research team has demonstrated that the viral reservoir of HIV-1 infection is established strikingly early after intrarectal simian immunodeficiency virus (SIV) infection of rhesus monkeys and before detectable viremia.         

Scientists Find New Clues to Brain’s Wiring

July 18, 2014 2:14 pm | News | Comments

New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. These synapses allow nerve cells to transmit and process information involved in thinking and moving the body.     

Managing Ecosystems via Genomics

July 18, 2014 2:11 pm | News | Comments

A cross-disciplinary team is calling for public discussion about a potential new way to solve longstanding global ecological problems by using an emerging technology called “gene drives.” The advance could potentially lead to powerful new ways of combating malaria and other insect-borne diseases.

New Gene Discovered that Stops the Spread of Deadly Cancer

July 18, 2014 2:01 pm | Videos | Comments

Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world's deadliest cancers. By identifying the cause of this metastasis—which often happens quickly in lung cancer and results in a bleak survival rate—Salk scientists are able to explain why some tumors are more prone to spreading than others.

Danish DNA Could be Key to Happiness

July 18, 2014 1:49 pm | News | Comments

Economists at the University’s Centre for Competitive Advantage in the Global Economy (CAGE) have looked at why certain countries top the world happiness rankings. In particular they have found the closer a nation is to the genetic makeup of Denmark, the happier that country is. The research could help to solve the puzzle of why a country like Denmark so regularly tops the world happiness rankings.

Scientists Identify Gene that Plays a Surprising Role in Combating Aging

July 18, 2014 1:44 pm | News | Comments

It is something of an eternal question: Can we slow or even reverse the aging process? Even though genetic manipulations can, in fact, alter some cellular dynamics, little is known about the mechanisms of the aging process in living organisms. Now scientists from the Florida campus of The Scripps Research Institute have found in animal models that a single gene plays a surprising role in aging that can be detected early on in development.

'Support Cells' in Brain Play Important Role in Down Syndrome

July 18, 2014 1:36 pm | News | Comments

Researchers have identified a group of cells in the brain that they say plays an important role in the abnormal neuron development in Down syndrome. After developing a new model for studying the syndrome using patient-derived stem cells, the scientists also found that applying an inexpensive antibiotic to the cells appears to correct many abnormalities in the interaction between the cells and developing neurons.

Gene Variation May Modify Cardiovascular Benefit of Aspirin

July 18, 2014 1:01 pm | News | Comments

A daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease. Now, a new study suggests that common genetic variation may modify the cardiovascular benefit of aspirin.                

Researchers Uncover New Cancer Cell Vulnerability

July 18, 2014 12:52 pm | News | Comments

Researchers have uncovered a genetic vulnerability of cancer cells that express telomerase— an enzyme that drives their unchecked growth— and showed that telomerase-expressing cells depend upon a gene named p21 for their survival.      

ISSCR: Promising Stem Cell Clinical Trials

July 17, 2014 1:22 pm | by Bioscience Technology Staff | Articles | Comments

Many promising clinical trials were highlighted at the annual meeting of the International Society of Stem Cell Research (ISSCR). One set of trials highlighted were monogenic gene therapy trials and cancer immunotherapy trials. Also discussed were trials for Parkinson’s disease, Multiple Sclerosis, and potential future trials involving cochlear stem cells.

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