The first human volunteer will receive red blood cells cultured in the laboratory within the...
If you follow cancer biology, then you’ve probably heard of ubiquitin before. In a recent paper...
A team of scientists published details of how a class of drugs called “HDACis” drive muscle-cell regeneration in the early stages of dystrophic muscles, but fail to work in late stages. The findings are key to furthering clinical development of HDACis for Duchenne muscular dystrophy (DMD), an incurable muscle-wasting disease.
Scientists at the University of Basel report first ever successful nose reconstruction surgery using cartilage grown in the laboratory. Cartilage cells were extracted from the patient’s nasal septum, multiplied and expanded onto a collagen membrane. The so-called engineered cartilage was then shaped according to the defect and implanted.
Synthetic collagen invented at Rice University may help wounds heal by directing the natural clotting of blood. The material, KOD, mimics natural collagen, a fibrous protein that binds cells together into organs and tissues. It could improve upon commercial sponges or therapies based on naturally derived porcine or bovine-derived collagen now used to aid healing during or after surgery.
Scientists are attempting to build a human heart with a 3-D printer. Ultimately, the goal is to create a new heart for a patient with their own cells that could be transplanted. It is an ambitious project to first, make a heart and then get it to work in a patient, and it could be years — perhaps decades — before a 3-D printed heart would ever be put in a person.
The more cups of coffee a person drank, the lower the risk for developing hepatocellular carcinoma (HCC), the most common type of liver cancer, according to new research.
When NASA sends an identical twin to the International Space Station next year, a Colorado State University researcher will be among just a few hand-picked scientists studying him and his brother to measure impacts of space travel on the human body.
An antimicrobial agent found in common household soaps, shampoos, and toothpastes may be finding its way inside human noses where it promotes the colonization of Staphylococcus aureus bacteria and could predispose some people to infection.
In a north London hospital, scientists are growing noses, ears and blood vessels in a bold attempt to make body parts in the laboratory. It's far from the only lab in the world that is pursuing the futuristic idea of growing organs for transplant. But the London work was showcased Tuesday as Mayor Boris Johnson announced a plan to attract more labs to do cutting-edge health and science research in the area.
Researchers have devised a way to quickly bring to the clinic the technique of using blood samples to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient’s body and responses to treatment.
Scientists may have discovered a new way to treat a type of childhood brain tumor that has proved incurable up until now, according to a recent study.
Researchers have generated a 3-D model of the human malaria parasite genome at three different stages in the parasite’s life cycle— the first time such 3-D architecture has been generated during the progression of the life cycle of a parasite.
A research team was able to demonstrate for the first time that caffeine has a positive effect on tau deposits in Alzheimer's disease. Tau deposits, along with beta-amyloid plaques, are among the characteristic features of Alzheimer's disease.
In their pursuit of understanding how pain works at the molecular level, a research team has found a new function for MicroRNAs, short stretches of genetic material that signal genes to turn on or off.
Chances are you've heard of mapping genes to diagnose rare diseases, predict your risk of cancer and tell your ancestry. But to uncover food poisonings? The nation's disease detectives are beginning a program to try to outsmart outbreaks by routinely decoding the DNA of potentially deadly bacteria and viruses.
Scleroderma is a rare and often fatal disease, causing the thickening of tissue, which currently lacks a cure and any effective treatments. A group of researchers, including a Michigan State University professor, is looking to change that. Neubig, along with several of his colleagues from the University of Michigan, have identified the core signaling pathway that activates the disease and the chemical compounds that can turn it off.
University of Utah neuroscientists report that when a region of the brain called the lateral habenula is chronically inactivated in rats, they repeatedly drink to excess and are less able to learn from the experience. The study has implications for understanding behaviors that drive alcohol addiction.
New research from Wake Forest Baptist Medical Center suggests that physicians are ordering vitamin D deficiency screening tests for preventive care purposes rather than after patients develop conditions caused by decreased bone density.
Clinical investigators at the Children’s Hospital of Eastern Ontario (CHEO) have developed a new screening tool to help diagnose obstructive sleep apnea in children. Evidence suggests that adults with a large neck circumference are more likely to develop obstructive sleep apnea (OSA), especially males. As neck circumference varies by age and sex, there have been no reference ranges to diagnose pediatric OSA up until now.
Researchers at King’s College London and Imperial College London have discovered that people with fewer copies of a gene coding for a carb-digesting enzyme may be at higher risk of obesity. The findings suggest that dietary advice may need to be more tailored to an individual’s digestive system, based on whether they have the genetic predisposition and necessary enzymes to digest different foods.
Neuroscientists report they have identified what they believe is the cause of the vast disintegration of a part of the brain called the corpus striatum in rodents and people with Huntington’s disease: loss of the ability to make the amino acid cysteine.
A team of researchers believe their findings could have important implications for the way that rheumatoid arthritis is diagnosed and treated. They say that more accurate clinical testing is now needed to better identify rheumatoid arthritis and to prevent it being misdiagnosed.
The formula for peak exercise heart rate that doctors have used for decades in tests to diagnose heart conditions may be flawed because it does not account for differences between men and women, new research says.
A small study that examined brains from children who died found abnormal patterns of cell growth in autistic children. The research bolsters evidence that something before birth might cause autism, at least in some cases.
For the millions of people forced to rely on a plastic tube to eliminate their urine, developing an infection is nearly a 100 percent guarantee after just four weeks. But with the help of a little bubble-blowing, biomedical engineers hope to bring relief to urethras everywhere.
Researchers at University College London developed a new antibacterial material which has potential for cutting hospital acquired infections. The combination of two simple dyes with nanoscopic particles of gold is deadly to bacteria when activated by light - even under modest indoor lighting. And in a first for this type of substance, it also shows impressive antibacterial properties in total darkness.
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