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Mosaicism: Study Clarifies Parents as Source of New Mutations

July 31, 2014 3:36 pm | News | Comments

Scientists have long speculated that mosaicism plays a bigger role in the transmission of rare disease mutations than is currently known. Now, a study sheds new light on the frequency of mosaicism in genomic disorders and its influence on recurrence risk.

Engineering a Protein to Prevent Brain Damage from Toxic Agents

July 31, 2014 3:21 pm | News | Comments

Research at New York University is paving the way for a breakthrough that may prevent brain...

New Way to Generate Insulin-producing Cells in Diabetes

July 31, 2014 3:20 pm | Videos | Comments

A new study has found that a peptide called caerulein can convert existing cells in the pancreas...

Molecule Enhances Copper’s Lethal Punch Against Microbes

July 31, 2014 3:11 pm | News | Comments

Harnessing a natural process in the body that pumps lethal doses of copper to fungi and bacteria...

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Strict Genomic Partitioning by Biological Clock Separates Key Metabolic Functions

July 31, 2014 3:10 pm | News | Comments

Much of the liver’s metabolic function is governed by circadian rhythms—our own body clock—and UC Irvine researchers have now found two independent mechanisms by which this occurs. The study reveals new information about the body clock’s sway over metabolism and points the way to more focused drug treatments for liver disease and such metabolic disorders as obesity and diabetes.

How Is Depression Related to Dementia?

July 31, 2014 3:05 pm | News | Comments

A new study gives insight into the relationship between depression and dementia. The current study, which involved 1,764 people from the Religious Orders Study and the Rush Memory and Aging Project, indicates that the association of depression with dementia is independent of dementia-related brain changes.

Pesticide DDT Linked to Slow Metabolism, Obesity, and Diabetes

July 31, 2014 2:43 pm | News | Comments

Exposure of pregnant mice to the pesticide DDT is linked to an increased risk of obesity, diabetes, high cholesterol, and related conditions in female offspring later in life, according to a study led by the University of California, Davis.

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FDA to Start Regulating Lab-developed Tests

July 31, 2014 12:24 pm | by Matthew Perron - AP Health Writer - The Associated Press | News | Comments

The Food and Drug Administration says it will begin regulating laboratory-developed tests, a growing class of medical diagnostics that have never before been subject to federal oversight.                  

Scientists Zoom In and Out as Brain Processes Sound

July 31, 2014 12:00 pm | News | Comments

Researchers have mapped the sound-processing part of the mouse brain in a way that keeps both the proverbial forest and the trees in view. Their technique allows zooming in and out on views of brain activity within mice, and it enabled the team to watch brain cells light up as mice “called” to each other.

Drug Target Identified for Common Childhood Blood Cancer

July 31, 2014 12:00 pm | News | Comments

In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers report that they have identified a possible new drug target for treating the disease. 

Dissolvable Fabric Loaded with Medicine Might Offer Faster Protection Against HIV

July 31, 2014 9:27 am | News | Comments

University of Washington bioengineers have discovered a potentially faster way to deliver a topical drug that protects women from contracting HIV. Their method spins the drug into silk-like fibers that quickly dissolve when in contact with moisture, releasing higher doses of the drug than possible with other topical materials such as gels or creams.

Birth Weight and Breastfeeding Have Implications for Children’s Health Decades Later

July 31, 2014 9:20 am | News | Comments

Young adults who were breastfed for three months or more as babies have a significantly lower risk of chronic inflammation associated with cardiovascular and metabolic diseases, according to research from the Brown School at Washington University in St. Louis.

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Kids with Autism, SPD Show Differences in Brain Wiring

July 31, 2014 8:30 am | News | Comments

Researchers have found that children with sensory processing disorders have decreased structural brain connections in specific sensory regions different than those in autism, further establishing SPD as a clinically important neurodevelopmental disorder.

Same Cancer, Different Time Zone

July 31, 2014 8:30 am | News | Comments

Just as no two people possess the same genetic makeup, a recent study has shown that no two single tumor cells in breast cancer patients have an identical genome.                          

Bioscience Technology This Week #4: Gold Nanoparticles Show Promise for Drug Delivery

July 30, 2014 2:02 pm | Videos | Comments

On this episode of Bioscience Technology This Week, Editor-in-Chief Rob Fee reports on gold nanoparticles' promise in drug delivery. Our second story examines the work being done to decipher the wheat genome and the implications of this work.

Team Makes Cancer Glow to Improve Surgical Outcomes

July 30, 2014 1:49 pm | News | Comments

The best way to cure most cases of cancer is to surgically remove the tumor. The Achilles heel of this approach, however, is that the surgeon may fail to extract the entire tumor, leading to a local recurrence. With a new technique, researchers at the University of Pennsylvania have established a new strategy to help surgeons see the entire tumor in the patient, increasing the likelihood of a positive outcome.

Soy May Help Women’s Hearts If They Start Early

July 30, 2014 1:36 pm | News | Comments

A diet rich in soy may help feminine hearts, but timing matters, finds a new study. Lifelong soy consumption, similar to the diet of women in Asia, produces the least atherosclerosis. Switching to a Western diet after menopause leads to just as much atherosclerosis as a lifelong Western diet, and switching to soy from a Western diet after menopause helps only if there isn't much atherosclerosis already.

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Exploring 3-D Printing to Make Organs for Transplants

July 30, 2014 1:19 pm | News | Comments

Printing whole new organs for transplants sounds like something out of a sci-fi movie, but the real-life budding technology could one day make actual kidneys, livers, hearts and other organs for patients who desperately need them. Scientists are reporting new understanding about the dynamics of 3-D bioprinting that takes them a step closer to realizing their goal of making working tissues and organs on-demand.

Retinal Regeneration in Zebrafish

July 30, 2014 12:27 pm | Videos | Comments

Biologists are studying retinal regeneration in zebrafish to find ways to combat human eye diseases. The small, minnow-like fish have eyes that develop in a way very similar to humans, but have the ability to regenerate retinal cells following an injury.

New Study Looks at How Epigenetic Effects are Passed Down

July 30, 2014 12:22 pm | News | Comments

A new study demonstrates that the ‘memory’ of nutrition during pregnancy can be passed through sperm of male offspring to the next generation, increasing risk of disease for grandchildren as well. In other words, to adapt an old maxim, ‘you are what your grandmother ate.’

Midlife Problem Drinking Doubles Chance of Memory Issues

July 30, 2014 12:00 pm | News | Comments

A new study indicates that middle-aged adults with a history of problem drinking are more than twice as likely to suffer from severe memory impairment in later life.                         

Breaking News: Blood Test Could Predict Suicide Risk

July 30, 2014 8:30 am | News | Comments

Researchers say they have discovered a chemical alteration in a single human gene linked to stress reactions that could give doctors a simple blood test to reliably predict a person’s risk of attempting suicide.            

Deadly Melanoma Cases Jump 200%, Report Says

July 30, 2014 8:22 am | by Anne Flaherty - Associated Press - Associated Press | News | Comments

Stop sunbathing and using indoor tanning beds, the acting U.S. surgeon general warned in a report released Tuesday that cites an alarming 200 percent jump in deadly melanoma cases since 1973.                 

Advance in Capturing Elusive Circulating Tumor Cells

July 29, 2014 3:33 pm | by Cynthia Fox | Articles | Comments

When cancers spread into the bloodstream, they often take on different characteristics, requiring different therapies. But it is hard to find these rare blood-borne cells. So, relapsed patients often do not get personalized care. Now, researchers have come up with a solution that zeros in on elusive circulating tumor cells (CTCs).

New Gene Function Discovery Offers Clues to ALS

July 29, 2014 12:11 pm | News | Comments

Researchers have found a missing link that helps to explain how ALS, one of the world’s most feared diseases, paralyses and ultimately kills its victims. The breakthrough is helping them trace a path to a treatment or even a cure.       

LFMS Shows Immediate Results as Depression Treatment

July 29, 2014 11:55 am | News | Comments

Individuals with major depressive disorder or bipolar disorder who receive low-field magnetic stimulation (LFMS) show immediate and substantial mood improvement, researchers report.                    

Memory Relies on Astrocytes

July 29, 2014 11:46 am | Videos | Comments

When you're expecting something— like the meal you've ordered at a restaurant— or when or when something captures your interest, unique electrical rhythms called gamma oscillations sweep through your brain. New research shows that little known supportive cells in the brain known as astrocytes may in fact be major players that control these waves.

Cell's Recycling Center Implicated in Division Decisions

July 29, 2014 11:37 am | News | Comments

Researchers have identified a mechanism that overrides the cells’ warning signals, enabling cancers to continue to divide even without a robust blood supply.                           

New Protein Structure Could Help Treat Alzheimer’s

July 29, 2014 11:23 am | News | Comments

Bioengineers have designed a peptide structure that can stop the harmful changes of the body’s normal proteins into a state that’s linked to widespread diseases such as Alzheimer’s, Parkinson’s, heart disease, Type 2 diabetes and Lou Gehrig’s disease.

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