Cell Biology

Xeno-free Mesenchymal Stem Cell Osteogenic Differentiation Medium

May 22, 2013 1:15 pm | Product Releases | Comments

EMD Millipore, the Life Science division of Merck KGaA, Darmstadt, Germany, and Plasticell of London, UK, announced the availability of OsteoMAX-XF, a fully defined, xeno-free human mesenchymal stem cell differentiation medium for the differentiation of mesenchymal stem cells into osteocytes.

LISTED UNDER: Cellular Biochemistry

Animal Origin Free Collagenase/Neutral Protease Blends

May 6, 2013 11:41 am | Product Releases | Comments

Worthington's new Animal Origin Free (AOF) STEMzyme Collagenase/Neutral Protease (Dispase) Blends 1 and 2 are now available for primary and stem cell isolation, regenerative medicine, biopharma, and cell bioprocessing applications.

LISTED UNDER: Assay Development Reagents

Cell Sorting Based on RNA Detection in Living Cells

May 1, 2013 12:10 pm | by Don Weldon, Yuko Williams, Alex Ko, EMD Millipore Corporation | Articles | Comments

Identifying cell types and sorting cells based on RNA expression levels without any transfection reagents or intrusive sample preparation can improve live cell sorting efficiency, physiological relevance, and post-sorting survival rate. SmartFlare RNA detection probes can detect levels of RNA inside living cells, providing the ability to sort and propagate live cell populations based on gene expression levels.

LISTED UNDER: Flow Cytometers

Assay Kits with Exclusive Fluorophore

April 23, 2013 2:23 pm | Product Releases | Comments

Molecular Devices announced the launch of FLIPR Calcium 6 Assay Kits, the latest addition to their range of calcium assay kits to address diversified GPCR and ion channel targets. Featuring a proprietary fluorophore, the dye offers a highest quantum yield, delivering the greatest signal window available in a calcium assay kit.

LISTED UNDER: Cell-based Assays

Histology Equipment for Reduced Technician Fatigue

April 23, 2013 1:59 pm | Product Releases | Comments

Cole-Parmer’s line of histology equipment offers options for laboratories to save time and space, and reduce fatigue for the histology technician. The Tissue Embedding Station, which combines typical histology products into one module, requiring less benchtop space in the histology lab.

LISTED UNDER: Automated Tissue Processing Equipment

Live Cell Imaging Platform for Neural Stem Cell Microenvironment Control

April 17, 2013 11:40 am | by Paul Hung, PhD, Cindy Chen, PhD, Terry Gaige; Andrew Zayac, and Brandon Miller (EMD Millipore) | Articles | Comments

Neural stem cells are sensitive to microenvironmental cues, including cell-cell contact, cell-extracellular matrix interaction, nutrient and waste transport, and environmental oxygen composition. How these parameters affect the stem cells’ morphology, proliferation, and differentiation remains an open area for research.

LISTED UNDER: Neuroscience | Cellular Imaging

Human 3D Skin Models

April 10, 2013 1:36 pm | by Scott Hickman, Marketing Manager, Toxicology, BioReliance Corporation | Articles | Comments

The development of the 3D reconstructed human skin micronucleus (RSMN) assay is the first to overcome the limitations of traditional cell culture methods. It can provide a more biologically relevant result than standard 2D in vitro genotoxicity assays, since it provides a functional stratum corneum, which accounts for permeability and appears to have a normal dermal metabolic capability.

LISTED UNDER: Cell-based Assays

System for Human Cell Line Authentication and Sample Identification

April 3, 2013 1:41 pm | Product Releases | Comments

Promega launched GenePrint 10 System for human cell line authentication and sample identification. GenePrint 10 includes the eight loci recommended by the ANSI Standard (ASN-0002) Authentication of Human Cell Lines: Standardization of STR Profiling, plus Amelogenin for gender identification and the highly polymorphic D21S11 locus for additional power of discrimination.

LISTED UNDER: Standards

Renin Kits

March 30, 2012 7:02 am | Product Releases | Comments

AnaSpec, EGT Group, provides renin kits specific for mouse and rat—the SensoLyte 520 Mouse Renin Assay Kit and SensoLyte 520 Rat Renin Assay Kit. Using the company’s proprietary 5-FAM/QXL 520 fluorescence resonance energy transfer (FRET) peptide, all three assays are ideal for screening of renin inhibitors and for continuous assay of renin activity.

Recycling of Alzheimer’s Proteins Could Be Key to New Treatments

June 1, 2011 6:25 am | News | Comments

The formation of abnormal strands of protein called amyloid fibrils — associated with two dozen diseases ranging from Alzheimer’s to type-2 diabetes — may not be permanent and irreversible as previously thought.

LISTED UNDER: Neuroscience

JCI online early table of contents: May 2, 2011

May 2, 2011 9:41 am | by EurekAlert | News | Comments

(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, May 2, 2011, in the JCI: "Skin sensitivity to food allergens explained;" "Cells derived from different stem cells: same...