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The Lead

Apple's ResearchKit - The Real Impact on Clinical Trials

April 28, 2015 8:59 am | by Merrilyn Datta, Ph.D., President and General Manager, Definiens | Articles | Comments

ResearchKit is being touted as having immense implications for the future of clinical trials.

An End to Cancer Pain?

April 27, 2015 9:55 am | by University of Toronto | News | Comments

A new study has discovered the trigger behind the most severe forms of cancer pain.

Promising Stem Cell Therapy

April 27, 2015 9:32 am | by Harvard Gazette | News | Comments

Animal model of breast-to-brain cancer spread allows testing of therapeutic-cell approach.

Some Progestins May Hike Cancer; Some Estrogens May Ward it Off

April 24, 2015 4:03 pm | by Cynthia Fox, Science Writer | Articles | Comments

A recent analysis of  long-term after-effects of a specific hormone replacement therapy (HRT)—...

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How to Identify Drugs That Work Best for Each Patient

April 24, 2015 9:39 am | by Anne Trafton, MIT | News | Comments

Implantable device could allow doctors to test cancer drugs in patients before prescribing chemotherapy.

Nerve Activity Stimulates Brain Tumor Growth

April 24, 2015 9:27 am | by Stanford University | News | Comments

New research shows that high-grade gliomas, the deadliest human brain tumors, increase their growth by hijacking some of the machinery of neuroplasticity, which normally helps the brain form new synapses.

Cirrhosis Deaths Drop 41 Percent from 2002 to 2012

April 22, 2015 10:43 am | by UNC | News | Comments

A new study has found dramatic improvements in the care of patients with cirrhosis and liver failure and recommends improved treatment strategies for patients with cirrhosis and concurrent bacterial infections.

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Researchers Test Blood-Based Biopsy for Finding Cancer

April 21, 2015 12:29 pm | by Ryan Bushey, Associate Editor | Articles | Comments

This method is delivering some promising results in early trials.

Immunotherapy is Not a Curiosity Anymore

April 20, 2015 1:58 pm | by Ryan Bushey, Associate Editor | Articles | Comments

One of the main sessions at this year’s Experimental Biology Conference in Boston was the Tang Prize Award lecture. 

Cell Type Responsible for Scarring, Skin-cancer Growth Identified

April 17, 2015 3:12 pm | by Stanford University | News | Comments

A single cell type in the skin of mice is a major contributor to scarring after wound healing or radiation damage, and facilitates the growth of melanoma. Blocking the cell’s activity in humans may be possible with currently approved drugs.

Angiogenesis Inhibitors Undermined by Immune Cells, Says Study

April 17, 2015 2:57 pm | by University of California San Francisco | News | Comments

Research suggests strategy to prevent relapse after therapies targeting tumor blood vessels.

Study Describes First Steps in Basic Biological Process that Could Be Used to Harness Therapeutic Cells

April 17, 2015 2:23 pm | by University of Penn Medicine | News | Comments

Understanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves.

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Nanoparticles at Specific Temperature Stimulate Antitumor Response

April 17, 2015 9:59 am | by Dartmouth College | News | Comments

Dartmouth researchers identify precise heat to boost immune system against cancer tumors.

Rare, Deadly Lymphoma Demystified

April 16, 2015 10:46 am | by Columbia University | News | Comments

Findings identify a cause of the disease and highlight potential therapeutic approach.

Study Questions Accuracy of Certain Tumor-only Gene Mapping

April 16, 2015 9:23 am | by Lauran Neergaard, Medical Writer, Associated Press | News | Comments

More cancer patients are getting the genes in their tumors mapped to help guide their treatment. New research suggests that isn't always accurate enough, and a second test could help ferret out the culprit genes.

Wearable Device Slows Deadly Brain Tumors

April 15, 2015 9:14 am | by University of Virginia | News | Comments

A wearable device that emits low-level electrical fields can slow the progression of glioblastoma, the deadliest form of brain cancer, and extend patients’ lifespans.

A Guide to Targeted NGS: Generating Accurate Data for Personalized Medicine

April 15, 2015 8:57 am | by Ellen Prediger, Ph.D., Senior Writer, Integrated DNA Technologies (IDT) | Articles | Comments

As personalized medicine is integrated into mainstream medical treatment, sequencing clinically relevant genes using the latest next generation sequencing (NGS) technologies will prove instrumental in guiding clinicians towards informed treatment decisions.

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Recruiting the Entire Immune System to Attack Cancer

April 14, 2015 10:59 am | by Anne Trafton, MIT | News | Comments

Stimulating both major branches of the immune system halts tumor growth more effectively.

Gold By Special Delivery Intensifies Cancer-killing Radiation

April 14, 2015 10:48 am | by Brown University | News | Comments

Researchers at Brown and URI have demonstrated what could be a more precise method for targeting cancer cells for radiation. Cancer-seeking peptides ferry nanoparticles of gold to the site. The gold then helps focus radiation on the cancer cells.

Cancer Surge in China Prompts Rise of Special Patient Hotels

April 13, 2015 9:04 am | by Jack Chang, Associated Press | News | Comments

Li Xiaohe has set herself up for the long haul in a cramped but sunny room in western Beijing, about a block from China's most renowned cancer hospital. Her laundry dries on hangers and her husband cooks in a communal kitchen as she embarks on an 84-day program of chemotherapy, following the removal of part of her right breast.

Lower Survival Rates Connected With High-risk Melanoma With Mutations, Study Finds

April 10, 2015 9:57 am | by UNC | News | Comments

A UNC Lineberger-led study found that people with higher-risk melanoma containing either BRAF or NRAS gene mutations had lower survival rates.

Genetic Screening Could Improve Breast Cancer Prevention

April 10, 2015 9:26 am | by The Institute of Cancer Research | News | Comments

A test for a wide range of genetic risk factors could improve doctors’ ability to work out which women are at increased risk of developing breast cancer, a major study of more than 65,000 women has shown.

Biologists Identify Brain Tumor Weakness

April 9, 2015 10:01 am | by Anne Trafton, MIT | News | Comments

Discovery could offer a new target for treatment of glioblastoma.

Researchers Discover Novel Mechanism Controlling Lung Cancer Stem Cell Growth

April 8, 2015 10:36 am | by H. Lee Moffitt Cancer Center & Research Institute | News | Comments

Moffitt Cancer Center researchers discovered a novel mechanism that plays an important role in the maintenance of lung cancer stem cells. This finding may lead to new potential therapeutic targets.

The First Personalized Genomic Cancer Vaccines

April 8, 2015 9:10 am | by Cynthia Fox, Science Writer | Articles | Comments

The first personalized cancer vaccine using genomics to define targets elicits robust immune responses, says a recent Science study.

Using Sound Waves to Detect Rare Cancer Cells

April 7, 2015 9:08 am | by Anne Trafton, MIT | News | Comments

Acoustic device can rapidly isolate circulating tumor cells from patient blood samples.

Cancer Genes Turned Off in Deadly Brain Cancer

April 6, 2015 2:30 pm | by Marla Paul, Northwestern University | News | Comments

New therapy approach goes directly to the source of cancer development.

How Immune Cells Facilitate the Spread of Breast Cancer

March 30, 2015 5:10 pm | News | Comments

The body's immune system fights disease, infections and even cancer, acting like foot soldiers to protect against invaders and dissenters. 

Fasting, Less-Toxic Cancer Drug May Work as Well as Chemotherapy

March 30, 2015 5:05 pm | by USC | News | Comments

Fasting in combination with chemotherapy has already been shown to kill cancer cells, but a pair of new studies in mice suggests that a less-toxic class of drugs combined with fasting may kill breast, colorectal and lung cancer cells equally well.

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