Nearly 50 years after the “war on cancer” was declared in the United States, precision medicine presages an era of increased understanding of the molecular basis of cancer and of the ability to design treatments tailored to a patient’s own genetic profile, a panel of experts said.
Results of a study suggest that MRI could one day make biopsies more effective or even replace...
Immune system response isn't as crucial as activity of the infected cells themselves.
Scientists at UCLA’s California NanoSystems Institute and Jonsson Comprehensive Cancer Center...
The biotech firm is making a big bet on precision medicine.
New labeling on the world's most popular weed killer as a likely cause of cancer is raising more questions for an aerial spraying program in Colombia that underpins U.S.-financed efforts to wipe out cocaine crops.
Deadly familial stomach and lobular breast cancers could be successfully treated at their earliest stages, or even prevented, by existing drugs that have been newly identified by University of Otago cancer genetics researchers.
A Harvard University and Waterloo University team has found that a common breast cancer chemotherapy (chemo) can create stem-like cancer cells out of more differentiated tumor cells.
Highly sensitive genomic analysis of acute lymphoblastic leukemia cells reveals for the first time how the malignant cells evolve to cause relapse.
Obese women have around a 40 percent greater risk of developing a weight-related cancer in their lifetime than women of a healthy weight, according to new figures* released by Cancer Research UK Tuesday.
The human gut is a remarkable thing. Every week the intestines regenerate a new lining, sloughing off the equivalent surface area of a studio apartment and refurbishing it with new cells. This year researchers figured out a way to isolate and grow thousands of these elusive cells in the laboratory at one time.
Mental training exercises developed at the Jonsson Comprehensive Cancer Center have been shown to help mitigate the effects of "chemo brain"
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have confirmed the ribosome assembly process as a potentially fertile new target for anti-cancer drugs by detailing the essential function of a key component in the assembly process.
After a chance observation in the lab, researchers found a method that can force dangerous leukemia cells in the lab to mature into harmless immune cells called macrophages.
Many recent meta-studies find hormone replacement therapy lengthens life after all. This may be leading to a comeback for the once hugely popular menopause treatment.
First steps toward precision medicine for a deadly disease.
Scientists are eager to make use of stem cells’ extraordinary power to transform into nearly any kind of cell, but that ability also is cause for concern in cancer treatment. Malignant tumors contain stem cells, prompting worries among medical experts that the cells’ transformative powers help cancers escape treatment.
A multidisciplinary research team discovers how cells know to rush to a wound and heal it – opening the door to new treatments for diabetes, heart disease and cancer. Researchers at the University of Arizona have discovered what causes and regulates collective cell migration, one of the most universal but least understood biological processes in all living organisms.
Can a tetanus shot help treat brain cancer? A small study hints that it might.
Basal cell carcinomas develop mutations in a protein on the Hedgehog pathway to evade a common drug therapy. Targeting another portion of the pathway may be an effective alternative treatment.
One of every eight patients might benefit from highly successful lymphoma drugs.
Getting a new drug to market is difficult, but the U.S. Food and Drug Administration (FDA) offers a number of ways to help the process along for promising drugs that have potential against serious diseases. One of these options is designation as a breakthrough therapy. This year a number of these therapies are targeted at fighting cancer.
In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to better treatment, researchers have mapped the “genomic landscape” of these rare childhood tumors. Their genomic mapping has revealed unprecedented details, not only of the aberrant genetic and chromosomal changes that drive the cancer, but the sequence of those changes that trigger it.
Researchers have developed a new technique to understand the actions of key proteins required for cancer cells to proliferate.
Testing breast cancer cells for how closely they resemble stem cells could identify women with the most aggressive disease, a new study suggests.
A provocative study in mice suggests something as simple as breathing in extra oxygen might give immune cells a boost in attacking cancer.
Tumor recurrence following a period of remission is the main cause of death in cancer. The ability of cancer cells to remain dormant during and following therapy, only to be reactivated at a later time, frequently with greater aggressiveness, is one of the least-understood aspects of the disease.
Tiny particles embedded in gel can turn off drug-resistance genes, then release cancer drugs.
Genetically engineered T memory stem cells (Tscm) can last more than 12 years in patients’ bodies, and can continually generate appropriate T cell armies for them, says an innovative study looking at two historic clinical trials.
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