People living with HIV will be treated with genetically engineered stem cells next month by the team of Nobel Prize-winning immunologist David Baltimore, PhD, Robert Andrews Millikan Professor of Biology, California Institute of Technology. The goal: to create, in patients, new immune systems resistant to HIV.
Yesterday, the RNA Institute at New York’s State University at Albany opened its doors to reveal...
For two years, stem cells slowed the progression of Lou Gehrig’s disease, a condition with a two...
Editors of PubPeer were used to getting only about 400 unique visits a day to their...
For less than $100, University of Washington researchers have designed a computer-interfaced drawing pad that helps scientists see inside the brains of children with learning disabilities while they read and write. To create the system, researchers hollowed out a ballpoint pen and inserted two optical fibers that connect to a light-tight box in an adjacent control room where the pen’s movement is recorded.
Researchers eradicated most melanoma tumors by exposing them to a fast-acting virus, according to a report in the Journal of Virology. Melanoma is the deadliest type of skin cancer and can spread throughout the body and even into the brain.
Researchers have identified a way to trigger reproduction in the laboratory of clusters of human cells that make insulin, potentially removing a significant obstacle to transplanting the cells as a treatment for patients with type 1 diabetes.
A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, new research reports. Metastasis is responsible for 90 percent of cancer-related deaths.
The Supreme Court ruled today that companies cannot patent parts of naturally-occurring human genes, a decision with the potential to profoundly affect the emerging and lucrative medical and biotechnology industries. The high court's unanimous judgment reverses three decades of patent awards by government officials.
At least among mice, females have innate protection from certain digestive conditions, according to a new study. While it’s tricky to draw conclusions for human health, the findings could eventually help scientists better understand and treat the 1.4 million Americans suffering from inflammatory bowel diseases, or IBD.
Scientists have discovered a previously undetected layer in the cornea, the clear window at the front of the human eye. The breakthrough could help surgeons to dramatically improve outcomes for patients undergoing corneal grafts and transplants.
New breakthroughs in research on protein-DNA recognition may have profound implications for furthering research into cancer and other genetically based diseases. The research— which integrates two fields, genomics and structural biology— sheds light on the mechanisms underlying how proteins recognize their DNA binding sites by translating genome sequences into three-dimensional structures.
Scientists have discovered a cellular process used by animals when a tissue is stressed and in molecular trouble from the expression of misfolded and damaged proteins: The tissue at risk attends to the trouble itself but also wisely calls out for help.
In a first-of-its-kind operation in the United States, a team of doctors helped create a bioengineered blood vessel and transplanted it into the arm of a patient with end-stage kidney disease. The procedure is a milestone in the field of tissue engineering.
This year some 232,340 new cases of invasive breast cancer will be diagnosed in women. Some of these patients will succumb to the disease, while others survive. Part of the enormous disparity in outcome has to do with the differing ways diseases like cancer affect individuals based on various factors. According to new research, how we study an illness can also depend on a feature of the disease itself – one known as heterogeneity.
As pediatric specialists become increasingly aware that surgical anesthesia may have lasting effects on the developing brains of young children, new research suggests the threat may also apply to adult brains. Researchers recently reported that testing in laboratory mice shows anesthesia’s neurotoxic effects depend on the age of brain neurons– not the age of the animal undergoing anesthesia.
In the gonads of animals, genome parasites, such as transposons, pose a serious threat to evolutionary fitness. To protect genomic integrity, animals evolved the so-called piRNA pathway to silence the deleterious transposons. Researchers have now identified almost 50 genes that play important roles in the piRNA pathway of the fruit fly Drosophila melanogaster.
The genetic malady known as Fragile X syndrome is the most common cause of inherited autism and intellectual disability. Brain scientists know the gene defect that causes the syndrome and understand the damage it does in misshaping the brain's synapses, but how this abnormal shaping of synapses translates into abnormal behavior is unclear. Now, researchers believe they know.
Carl Zeiss Microscopy LLC, announces that it donated high-end research microscope instruments as part of an innovative training program at Children’s Hospital Los Angeles. The program brings minority Los Angeles area high school students into working laboratories, and entices them with the excitement of scientific discovery.
Intestinal bacteria may have a greater influence on us than was previously thought. In a recent study, researchers showed that patients with Type 2 diabetes have an altered gut microbiota. Their findings have led to a new model to identify patients at increased risk of developing diabetes.
An amazing glow-in-the-dark cockroach, a harp-shaped carnivorous sponge and the smallest vertebrate on Earth are just three of the newly discovered top 10 species selected by the International Institute for Species Exploration at Arizona State University.
Three New York University researchers from China divulged results from a federally funded study to Chinese competitors in exchange for tuition, rent and other expenses, federal prosecutors say. Yudong Zhu, a U.S.-educated NYU professor, and Xing Yang, a lab engineer, were released on bail after appearing in federal court in Manhattan to face commercial bribery and other charges. They left court without speaking to reporters.
The worm’s tail wriggles, a micrometer-scale twitch. A scanner captures the new posture. Software recognizes the motion. Life goes on in the Lifespan Machine, a new system devised in the lab of Walter Fontana that, essentially, counts dead worms.
Scientists have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, they now have evidence that the bone underneath the cartilage is also a key player and exacerbates the damage.
Injectable nanoparticles developed at MIT may someday eliminate the need for patients with Type 1 diabetes to constantly monitor their blood-sugar levels and inject themselves with insulin. The nanoparticles were designed to sense glucose levels in the body and respond by secreting the appropriate amount of insulin, thereby replacing the function of pancreatic islet cells, which are destroyed in patients with Type 1 diabetes.
A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings may pave the way to a new treatment for Alzheimer's disease in humans.
A team of researchers has invented a method for repairing damaged peripheral nerves. Through a biodegradable implant in combination with a newly-developed Guiding Regeneration Gel (GRG) that increases nerve growth and healing, the functionality of a torn or damaged nerve could ultimately be restored.
In any laboratory, safety of both the researchers and the samples are integral to a successful experiment. Fume hoods and biological safety cabinets offer protection from hazardous fumes with proper ventilation that will ensure the safety of all scientists in the laboratory and the samples they are working with.
Researchers have identified a protein in the blood of mice and humans that may prove to be the first effective treatment for the form of age-related heart failure that affects millions of Americans. When the protein was injected into old mice, the hearts were reduced in size and thickness, resembling the healthy hearts of younger mice.