Proteomics
Abbott Laboratories and Celera Genomics to Collaborate on Cancer Therapeutics 7/21/04
July 21, 2004 6:16 am | Articles | CommentsBy Mark Terry Abbott Laboratories, Abbott Park, Ill., and Celera Genomics, Rockville, Md., have announced a strategic collaboration to develop and commercialize potential cancer treatments.
Israeli Genomics Company Spin-Off to Focus on Small Molecule Drug Discovery 7/19/04
July 19, 2004 5:27 am | Articles | CommentsBy Mark Terry Compugen Ltd., Tel Aviv, Israel, announced that it has spun off its chemistry division into a subsidiary, Keddem Biosciences Ltd., to be located in Ashkelon, Israel.
Reagent Dispenser (3617)
July 13, 2004 10:30 am | Articles | CommentsThe Multidrop® Micro, the latest member of the Multidrop reagent dispenser family, is now optimized for dispensing protein-containing solutions. This dispensing cassette also can be used for solutions such as 100% DMSO and viscous liquids, as well as applications in genomics and proteomics.
Multimode Detectors (3613)
July 13, 2004 10:30 am | Articles | CommentsThe DTX Series of detectors combines absorbance, fluorescence, and luminescence detection in one instrument.
Conjugation Chemistry
July 12, 2004 10:48 am | Articles | CommentsHydraLinK conjugation chemistry is selective, stable in solution, and not susceptible to non-specific binding.
Rapid Fractionation Of Complex Protein Extracts With Centrifugal MembraneAdsorber Units Improves Detection Of Proteins In 2d Page
May 19, 2004 10:51 am | Articles | CommentsTwo-dimensional gel electrophoresis followed by mass spectrometry for protein identification is a reliable and reproducible means of sample analysis. A key element in this process is reducing sample complexity, as samples often consist of tens of thousands of proteins in a magnitude of different concentrations.
LC System For Proteomics
May 5, 2004 4:48 am | Articles | CommentsAgilent 1100 Series liquid chromatography (LC) micro collection/spotting system, a complete software-controlled product, features direct spotting on matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) targets.
Protein Kinase Images Speed Drug Discovery
May 5, 2004 4:48 am | Articles | CommentsBSI Proteomics is able to provide high resolution images of the drug binding site of protein kinases, which provides a more accurate model for rational drug design. Dynamic Crystallization™ technologies provide structures of kinases.
Phenotype Array Speeds Research on Bioremediation Bugs 5/3/04
May 3, 2004 1:12 pm | Articles | Commentsby Elizabeth Tolchin As part of the Genomics:GTL (formerly Genomes to Life) project, funded by the US Department of Energy, researchers from Lawrence Berkeley National Laboratory, Berkeley, Calif., are using phenotype microarrays to rapidly deduce the stress-response pathways in metal- and radionuclide-reducing bacteria.
Mapping Brain Genes in 3D 4/20/04
April 20, 2004 1:02 pm | Articles | Commentsby Elizabeth Tolchin Researchers at the University of Illinois, Chicago, are developing an interactive gene expression map of the brain, as part of The Human Brain Project (HBP).
Mississippi Takes on Tobacco-based High-Volume Antibody Expression 4/14/04
April 14, 2004 10:57 am | Articles | Commentsby Robert Ford A five-year agreement between Mississippi State University (MSU), Starkville, Miss., and Toxin Alert Inc., Toronto, Canada, plans to provide research funding to the university for the development of large-scale antibody production in tobacco plants.
Proteomic Imaging System
April 12, 2004 7:48 am | Articles | CommentsProXPRESS™ 2D Proteomic Imaging System features a high-speed CCD-based imaging camera. The system, part of the PerkinElmer High Content Proteomics product suite, identifies and quantifies low abundant and hard-to-see proteins in gels.
MALDI Ion Source For Proteomics
April 12, 2004 7:46 am | Articles | CommentsFinnigan vMALDI™ ion source (Thermo Electron Corp.) enhances the Finnigan™ LTQ™ linear ion trap mass spectrometer for use in proteomics research.
Multimode Detectors
April 12, 2004 7:46 am | Articles | CommentsDTX Series multimode detectors, from Beckman Coulter, combine absorbance, fluorescence and luminescence detection in one instrument.
Antibody Technology Sprouts Start-Up in Texas Panhandle 3/31/04
March 31, 2004 11:57 am | Articles | Commentsby Elizabeth Tolchin By developing a novel antibody drug discovery technology, researchers from Texas Tech University, Amarillo, Texas, spawned a start-up firm, now six weeks young. Venture capital firm Emergent Technologies Inc., Austin, Texas, licensed the technology from the university and formed the start-up, Receptor Logic Ltd.
Expression, Interaction and Structure Unite in Proteomics Research System 3/11/04
March 11, 2004 12:16 pm | Articles | Commentsby Elizabeth Tolchin A new bioinformatics tool, the Proteomics RIMS (Research Information Management System), announced by Bruker BioSciences Corp. at this week's Pittcon 2004 conference in Chicago, promises the integration of the instrumentation and data analysis associated with proteomics and structure-based research.
An Entry Level Liquid Handler 2/4/04
February 6, 2004 4:44 am | Articles | Commentsby Chris Dickey, DrPH Looking to extend its reach into academic and small biotechnology laboratories, Beckman Coulter Inc., Fullerton, Calif., introduced a smaller and less expensive version of its Biomek FX liquid handling system at the LabAutomation 2004 meeting in San Jose, Calif.
Improved Resolution for Basic Range Proteins Using Large Format 2-D Electrophoresis
January 13, 2004 3:57 am | Articles | Comments2-D gel electrophoresis (2DGE) is a widely used protein analysis tool. When it is applied to the separation of basic proteins (pH 7-10), achieving good resolution can be a challenge.
Nuclear Magnetic Resonance In Structural Proteomics
January 12, 2004 12:24 pm | Articles | CommentsAfter nearly four decades of advancements in both technology and methodology, Nuclear Magnetic Resonance (NMR) spectroscopy now plays an important role in
Streamlined Proteomics Data Analysis
January 12, 2004 11:36 am | Articles | CommentsEnabling accelerated processing of complex proteomics data, this streamlined proteomics data
Assigning Functions Through Genetic Networks 12/19/03
December 19, 2003 10:59 am | Articles | Commentsby Elizabeth Tolchin Under the hypothesis that 'conserved coexpression' could serve as an indicator of gene function on a genomic level, a team from Israel developed a model for comparing gene expression data and genomic sequence information across several different species at once.
Cold Probe Puts a Fire Under NMR 11/26/03
November 26, 2003 5:11 am | Articles | Commentsby Elizabeth Tolchin Studying proteins at physiological conditions that are close to that in living cells often requires diluted nuclear magnetic resonance (NMR)
Building a Better Binding Ligand from Fluorescent Proteins 11/25/03
November 25, 2003 7:10 am | Articles | Comments11/25/03Researchers fashioned a superior binding ligand from altered green fluorescent proteins (GFPs) that combines the high affinity and specificity of antibodies with the fluorescence that is ideal for detection.
Researchers Map Protein Interactions in Fruit Flies 11/21/03
November 18, 2003 5:00 am | Articles | Commentsby Elizabeth Tolchin Using the recently available Drosophila melanogaster genome sequence, a group of researchers predicted a total of 14,202 transcripts and built a genome-scale protein interaction map.
Proteomics Research Products
October 15, 2003 11:35 am | Articles | CommentsProducts for proteomics research include an application for multiplexed capillary electrophoresis instruments, as well as a software analysis package. The new application automatically determines sizing and relative concentrations of proteins.
