Proteomics
Pre-spotted Proteomics Chip
March 15, 2005 8:58 am | Articles | CommentsPrespotted AnchorChip, a second-generation disposable MALDI target for gel-based and LC-MALDI-based expression proteomics, eliminates cross-contamination from previous samples and calibration spot preparation and reduces sample preparation time.
Avian IgY Antibody Conjugates For Proteomics Sample Processing
March 9, 2005 7:07 am | Articles | CommentsCharles River Proteomic Services Inc. (Worcester, MA) and GenWay Biotech Inc. (San Diego, CA) have collaborated to produce avian IgY polyclonal antibodies that function as a fractionation step prior to protein separation.
MALDI-TOF/TOF For Expression Proteomics, Biomarker Discovery
March 8, 2005 9:10 am | Articles | CommentsThe ultraflex II MALDI-TOF and TOF/TOF mass spectrometer (Bruker Daltonics) finds application in peptide de novo sequencing, the analysis of post-translational modifications, and top-down protein primary structure determination.
Weekly News Roundup 2/25/05
February 25, 2005 11:22 am | Articles | CommentsGenome of Deadly Pathogen Sequenced
Method for Localizing Proteins in Cells 1/26/05
January 26, 2005 11:40 am | Articles | CommentsComputationally spotting clusters from cell images
Weekly News Roundup 1/14/05
January 14, 2005 11:13 am | Articles | CommentsSharing Designs for custom microarrays
Experts Chat about Nanotechnology 1/12/05
January 12, 2005 10:16 am | Articles | CommentsA glimpse of what's ahead in medicine
Microarrays: Spotting The Future
January 12, 2005 9:35 am | Articles | CommentsMicroarray technology has come a long way since Affymax, predecessor to Affymetrix (Santa Clara, CA), introduced polypeptide arrays in the late 1980s. Today's gene, protein, and tissue arrays have evolved from research curiosities to the experimental platform of choice for many life scientists and clinical researchers - something akin to high-tech, ultraminiaturized microtiter plates.
Magnetic Bead
January 12, 2005 5:53 am | Articles | CommentsMagAB nanoparticle allows scientists to attach antibodies, antibody fragments, peptides, DNA or ligands to magnetic bead surfaces. The beads are valuable to researchers looking for specific proteins or binding partners, and for biologically selective and very sensitive specific clinical assays.
Fluorescent Dyes
December 28, 2004 8:07 am | Articles | CommentsMFP fluorescent dyes are ready for coupling to proteins and nucleic acids, and span the wavelength spectrum from green to far red. They offer photostability, a strong absorption, high fluorescence quantum yield and good water solubility.
Proteomics Software Provides 2D Gel Analysis
December 28, 2004 8:07 am | Articles | CommentsDymension software accurately analyzes 2D gels in seconds. A spot finding algorithm results in minimal post editing being needed and couples with an automatic gel alignment process to speed the whole imaging process right through to results and report generation.
Visual Computing System
December 28, 2004 8:06 am | Articles | CommentsSilicon Graphics Prism Linux OS-based computers combine standards-based Intel Itanium 2 processors, the Linux operating environment, and advanced graphics technology to addressing demanding visual computing problems.
LIMS Software Integrates Genomics, Proteomics Laboratories
December 28, 2004 8:06 am | Articles | CommentsLS*LIMS Software from Applied Biosystems increases lab productivity by integrating Applied Biosystems and third-party instrument interfaces, including the Applied Biosystems 3730 and 3730xl DNA Analyzers, the ABI PRISM 7900HT Sequence Detection System, and the GeneAmp PCR System 9700.
Proteomics Analysis Systems
December 14, 2004 9:17 am | Articles | CommentsThe Proteineer-LC is an LC-ESI-MALDI system for LC-based expression proteomics workflows. Its manufacturer, Bruker Daltonics, also offers Top-Down Proteineer capability on the apex-Qe Q-q-FTMS mass spectrometry system.
Weekly News Roundup 12/10/04
December 9, 2004 12:12 pm | Articles | CommentsNCI Supports Biomarker Discovery
Wyeth Adopts Translation Medicine 12/7/04
December 7, 2004 12:10 pm | Articles | CommentsStepping up biomarker discovery
Pharmacogenomic Package for Oncology 11/17/04
November 17, 2004 12:25 pm | Articles | CommentsIntegrated gene expression and genotyping technologies
Columns For LC-MS And 2D Chromatography
November 12, 2004 10:19 am | Articles | CommentsPolymer Laboratories has launched a range of capillary and micro chromatography columns for small-scale chromatography. Chemically stable polymeric particles do not leach either soluble or particulate species.
Tiling Transcription in the Genome 11/11/04
November 12, 2004 9:04 am | Articles | CommentsBy Elizabeth Tolchin
Liquid Chromatography/Mass Spectrometry System
October 1, 2004 4:40 am | Articles | CommentsInstrumentation, software, columns, and method protocols are integrated in this complete system for identification of proteins and biomarkers. A manual of optimized method protocols is included for each step of the MS-based proteomics workflow, from sample preparation to data analysis and reporting.
Tube Shows Minimal Affinity For Peptides And Proteins
September 23, 2004 6:42 am | Articles | CommentsSample preparation in biological and biotechnological systems plays an important role in the success of many processes. It is a requirement that the material of the micro test tubes used must possess low affinity for proteins and peptides to prevent adsorption of the sample material to the tube surface.
Integrated LC/MS System
August 16, 2004 7:51 am | Articles | CommentsMDLC LTQ LC/MS system (Thermo Electron Corp.) provides experimental flexibility and precision for proteomics solutions.
Dynamic Structural Determination Identifies Sequences Necessary for Centromere Formation
August 3, 2004 7:44 am | Articles | CommentsBy Catherine Shaffer - 8/03/04
Biomarker Chips
July 26, 2004 5:07 am | Articles | CommentsSerum Biomarker Chips facilitate profiling of serum biomarkers and discrimination of stages of disease progression. Detection of over- and under-abundant serum biomarkers has value in cancer research. Proteomics researchers can profile and pattern the molecular signature of human serum.
