Eksigent has announced the addition of a NanoLC MALDI Spotting System to its nanoflow chromatography product line. Featuring the new Ekspot spotter, the system complements the company’s existing offerings for nanospray mass spectrometry proteomics analysis.
Pathway Studio 5.0 software for pathway and molecular interaction analysis adds functionality for transcriptomics, metabolomics, and proteomics data interpretation. Key changes include the addition of Signaling Line Pathways for enhanced microarray data analysis.
With resolution of >500,000 and mass accuracy of <1 ppm, the 900-MS, an FT MS instrument, is used in proteomics and metabolomics analyses.
The AXIMA-TOF2 MALDI CID MS/MS (a TOF TOF mass spectrometer) includes intuitive software and XML data exporting as a standard features.
Induction Based Fluidics technology (IBF) is used to spot pico- to micro-size volumes of Liquid Chromatographic (LC) effluent into micro vials, micro-well plates or on MALDI targets while the ALIAS autosampler serves as the platform for the product.
BioRAPTR FRD microfluidic workstation (Beckman Coulter, Inc., Fullerton, CA) is offered in multiple configurations, including as a standalone unit and integrated with Beckman Coulter’s PARADIGM Detection Platform, Biomek NX p liquid handler and BRT Robotic Transport.
NanoQuot Microplate Dispenser utilizes control software for intuitive and flexible dispense program creation and liquid profile management, making it easy to quickly change dispense solutions characterized by different viscosities. A .
Listing of awarded and available funding
Source: Vanderbilt University Medical Center, Nashville
The rate of cancer incidence continues to remain stable while the death rate from cancer continues to decline, states the 2005 Cancer Trends Progress Report Update, published by the National Cancer Institute (NCI).
Source: University of Minnesota, Minneapolis
Source: Pacific Northwest National Laboratory, Richland, Wash.
Over 300 years ago, Anton van Leeuwenhoek discovered the secrets of building compound microscopes, and biologists have been obsessed with the minuscule ever since. It's an understandable fascination; from Streptococcus to sarcoma to sickle-cell, the biggest breakthroughs come from making sense of the small.
Proteomics Grade Trypsin Spin Column reduces the amount of time required to digest complex protein mixtures from as much as 18 hours with conventional methods to only 15 minutes.
Mass resolution and accuracy, sensitivity, analytical versatility and reliability have been enhanced in the new autoflex III smartbeam mass spectrometers for use in expression proteomics and quantitative proteomics, as well as in peptide/protein biomarker discovery, identification and validation.
PromoFluor dyes span the wavelength spectrum from blue-green to far red. They provide photostability, strong absorption, high fluorescence quantum yield and water solubility. Dye intensity increases when coupled to biomolecules resulting in reduced influence of uncoupled dyes.
Imaging systems used for Western blot analysis are often described as 'quantitative'. While it is true that the instrumentation used to image the blots does acquire signal in a quantitative way, data produced by these systems can only be quantitative if the signal generated by the chemistry is proportional to the amount of sample on the blot in a linear fashion.
The clock ticks forward one second. A technician pipets a sample from a crude cellular extract, processes it through a complex preparation protocol with multiple reagents, runs the processed extract on a gel, isolates the desired bands, and characterizes the activities of several novel enzymes.
Proteomics-grade trypsin is prepared in a 15 minute digestion using the Trypsin Spin Column, Proteomics Grade. The ultra-micro spin column contains purified, TPCK-treated porcine trypsin immobilized on a spherical 20 micron silica support, chemically modified to minimize non-specific adsorption.
Somewhere, deep within a complex cell extract sample, sit the potential biomarker proteins Dr. Pierre Thibault is hoping to profile and characterize. The barrier to finding them? Everything else in the sample.
Proteus software now includes Automated Informatics, a technology framework that enables bioinformatics pipelining and analytics automation.
AXIMA-TOF 2 MALDI TOF-TOF mass spectrometer, a high-energy, collision induced dissociation (CID) MS/MS instrument, extends the type of analyses life science laboratories can provide. Intuitive software allows for use in open-access lab environments, requiring minimum user input.
CLINPROT FORUM supports customers in protein/peptide biomarker discovery and validation, as well as in clinical and applied proteomics.
Version 4.0 of PathwayStudio (formerly PathwayAssist, Ariadne Genomics, Inc.) contains new tools for microarray data analysis and pathway dynamics simulation, as well as over 1000 reconstructed pathways.
Integrated proteomics product line is offered for producing, imaging and analyzing 2D gels. IEF-SYS, a one-tank electrophoresis system, allows 2D gels to be run with both immobilized pH gradient strips and pre-cast acrylamide gels.