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The Lead

Cancer Drug Resistance Has an ‘Off Switch’

October 21, 2014 11:29 am | Videos | Comments

Scientists have uncovered details about how cancer is able to become drug resistant over time, a phenomenon that occurs because cancer cells within the same tumor aren’t identical.                     

Experimental Drug Restores Pleasure-seeking Behavior in Bipolar Patients

October 20, 2014 11:05 am | News | Comments

A drug being studied as a fast-acting mood-lifter restored pleasure-seeking behavior...

Copper May Be Prostate Cancer’s Fatal Flaw

October 15, 2014 3:13 pm | News | Comments

Researchers have found a way to kill prostate cancer cells by delivering a trove of copper...

Q&A: How Plasma Transfusions, Antibodies Fight Ebola

October 15, 2014 1:19 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

A Dallas nurse being treated for Ebola has received a plasma transfusion from a doctor who...

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Reversing Idiopathic Pulmonary Fibrosis

October 14, 2014 2:42 pm | by Cynthia Fox, Science Writer | Articles | Comments

Lethal fibrosis in lungs of mice with idiopathic pulmonary fibrosis (IPF) can be reversed, say researchers. No drug on the market can do this. But the crew pulled it off, in mice, by temporarily restoring (a mimic of) one of the body’s own anti-fibrosis agents, sharply reduced in IPF: microRNA-29.

Chemical from Broccoli Sprouts Promising Against Autism

October 14, 2014 11:41 am | News | Comments

Results of a small clinical trial suggest that a chemical derived from broccoli sprouts— and best known for claims that it can help prevent certain cancers— may ease classic behavioral symptoms in those with autism spectrum disorders (ASDs).   

Bacterial Defense Policies

October 13, 2014 2:14 pm | News | Comments

A research team has used high-resolution cryo-electron microscopy to obtain novel insights into the ultrastructural changes in an intracellular machine associated with the acquisition of resistance to the antibiotic erythromycin.      

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Researchers Begin Ebola Vaccine Study in Africa

October 9, 2014 5:52 pm | by The Associated Press | News | Comments

The first study of a possible Ebola vaccine is underway in Africa: University of Maryland researchers say three health care workers in Mali received the experimental shots.                       

Marburg, Ebola’s Relative, Cured in Monkeys

October 9, 2014 8:30 am | by Cynthia Fox, Science Writer | Articles | Comments

An experimental drug saved the lives of 16 of 16 monkeys with the Marburg virus, a killer near-indistinguishable from Ebola, which caused the death of a Ugandan health worker Oct. 6.                  

Gene Mutation Could Prevent Weight Gain from High-sugar Diet

October 7, 2014 1:38 pm | News | Comments

Imagine being able to take a pill that lets you eat all of the ice cream, cookies, and cakes that you wanted– without gaining any weight. New research found a new way to suppress the obesity that accompanies a high-sugar diet, pinning it down to a key gene that pharmaceutical companies have already developed drugs to target.

Green Tea-based ‘Missiles’ May Kill Cancer Cells

October 7, 2014 1:17 pm | News | Comments

Green tea has long been known for its anti-oxidant, anti-cancer, anti-aging and anti-microbial properties. Now, a group of researchers has taken the health benefits of green tea to the next level by using one of its ingredients to develop a drug delivery system.

Wine Antioxidant Slows Acne

October 1, 2014 3:28 pm | News | Comments

Got grapes? UCLA researchers have demonstrated how resveratrol, an antioxidant derived from grapes and found in wine, works to inhibit growth of the bacteria that causes acne. The team also found that combining resveratrol with a common acne medication, benzoyl peroxide, may enhance the drug's ability to kill the bacteria and could translate into new treatments.  

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Early Antibiotic Use Linked to Childhood Obesity Risk

September 30, 2014 2:22 pm | News | Comments

The use of broad-spectrum antibiotics by children before the age of 24 months was associated with increased risk of obesity in early childhood, according to a new study.                       

Drug and Device Firms Paid $3.5B to Care Providers

September 30, 2014 2:02 pm | by Ricardo Alonso-Zaldivar - Associated Press - Associated Press | News | Comments

Striving to shine a light on potential ethical conflicts in medicine, the Obama administration is releasing data on drug company payments to tens of thousands of individual doctors.                    

Chemists Recruit Anthrax to Deliver Cancer Drugs

September 26, 2014 8:30 am | News | Comments

Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. A team of researchers has now hijacked that delivery system for a different purpose: administering cancer drugs.

Airway Muscle-on-a-chip Mimics Asthma

September 23, 2014 1:46 pm | News | Comments

Hope for healthier airways may be on the horizon thanks to a human airway muscle-on-a-chip that could be used to test new drugs because it accurately mimics the way smooth muscle contracts in the human airway, under normal circumstances and when exposed to asthma triggers.

White House Orders Plan for Antibiotic Resistance

September 19, 2014 8:30 am | by Mary Clare Jalonick - Associated Press - Associated Press | News | Comments

Signaling the seriousness of the threat posed by antibiotic-resistant germs, President Barack Obama on Thursday ordered the government to create a national plan to fight them by early 2015.                  

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Vitiligo Treatment Holds Promise for Restoring Skin Pigmentation

September 18, 2014 2:35 pm | Videos | Comments

A treatment regimen is safe and effective for restoring skin pigmentation in vitiligo patients, according to a new study. Patients were randomly divided into two study groups: Group A received a combination therapy; Group B received only NB UVB treatment.

Kids' Poisonings Linked to Anti-addiction Medicine

September 15, 2014 12:34 am | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

An anti-addiction drug used to fight the nation's heroin and painkiller abuse epidemics poses a threat to young children who accidentally swallow relatives' prescriptions, a federal study says. Some children have died.          

BST This Week #15: Bees May be Key to Antibiotic Alternatives

September 12, 2014 8:30 am | Videos | Comments

On this episode of Bioscience Technology This Week, Christina Jakubowski explores the role that bees may play in the search for antibiotic alternatives. Our second story focuses on how increased carbon dioxide levels in water can rob sharks of their ability to sense the smell of food.

Two Anti-Ebola Vaccines in Historic Race

September 11, 2014 3:38 pm | by Cynthia Fox | Articles | Comments

One of the most rapidly fast-tracked vaccines in history— an anti-Ebola “ChAd3” vaccine— just started clinical trial in humans, and may be done as soon as November. But a second fast-tracked anti-Ebola vaccine— called an “rVSV” vaccine— is hot on its heels.

Gut Microbes Determine How Well Flu Vaccine Works

September 11, 2014 3:34 pm | News | Comments

Mice treated with antibiotics to remove most of their intestinal bacteria or raised under sterile conditions have impaired antibody responses to seasonal influenza vaccination, researchers have found.               

Using Antibiotics to Help Heart Problems

September 11, 2014 12:17 pm | News | Comments

A research team is looking at whether an antibiotic has the potential to prevent or treat irregular heartbeats brought on by other medicines, thanks to a grant from national charity in the UK.                 

Long-term Use of Anxiety, Sleep Meds Linked to Alzheimer's

September 10, 2014 11:41 am | News | Comments

Taking benzodiazepines (widely prescribed drugs to treat anxiety and insomnia) is associated with an increased risk of developing Alzheimer's disease, particularly for long-term users, suggests a new study.             

Mouse Studies Advance Treatment for Common Eye Diseases

September 8, 2014 3:40 pm | News | Comments

Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases.                       

ZMapp: Best Anti-Ebola Treatment Yet

September 4, 2014 3:05 pm | by Cynthia Fox | Articles | Comments

ZMapp, an experimental drug that may have already have saved a few patients in Africa, is the most effective anti-Ebola therapy yet, according to a recent Nature paper on rhesus macaques monkeys.              

Pharmacist Arrested in Tainted Steroid Case

September 4, 2014 11:25 am | by Denise Lavoie - AP Legal Affairs Writer - Associated Press | News | Comments

A pharmacist who oversaw the sterile clean rooms at a Massachusetts compounding pharmacy responsible for a deadly meningitis outbreak was arrested Thursday as he was about to board a flight for Hong Kong, federal officials said.      

U.S. to Begin Safety Testing Ebola Vaccine

August 28, 2014 9:23 am | by Seth Borenstein - AP Science Writer - Associated Press | News | Comments

Federal researchers next week will start testing humans with an experimental vaccine to prevent the deadly Ebola virus. The NIH announced today that it is launching the safety trial on a vaccine developed by the agency's National Institute of Allergy and Infectious Diseases and GSK.

New Restrictions on Hydrocodone to Take Effect

August 22, 2014 8:23 am | by The Associated Press | News | Comments

The federal government is finalizing new restrictions on hundreds of medicines containing hydrocodone, the highly addictive painkiller that has grown into the most widely prescribed drug in the U.S.               

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