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Gene May Predict Human Response to Antidepressants

December 11, 2013 11:15 am | News | Comments

Researchers have discovered a gene that may reveal whether people are likely to respond well to SSRI antidepressants, both generally and in specific formulations.                           

Gene Therapy Promising for Hemophilia

December 11, 2013 10:52 am | News | Comments

Researchers have found that a new kind of gene therapy led to a dramatic decline in bleeding events in dogs with naturally occurring hemophilia A.                             

'Bubble Boy' Disease Treated with Gene Therapy

December 9, 2013 12:44 pm | News | Comments

Researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated as part of an international clinical study of a new form of gene therapy.


Restoring 'Exhausted' HIV-fighting Immune Cells

December 3, 2013 12:35 pm | News | Comments

Researchers have identified a protein that causes loss of function in immune cells combatting HIV. The scientists report that the protein, Sprouty-2, is a promising target for future HIV drug development.                 

Killer Cocktail Fights Brain Cancer

November 25, 2013 2:53 pm | News | Comments

A novel immune-boosting drug combination eradicates glioblastoma brain cancer in mice, according to a new study.                                        

Team Creates 'Synthetic Antibodies'

November 25, 2013 12:05 pm | News | Comments

Chemical engineers have developed a novel way to generate nanoparticles that can recognize specific molecules, opening up a new approach to building durable sensors for many different compounds.                

New Link Between Obesity, Diabetes Found

November 21, 2013 12:15 pm | News | Comments

A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to new mouse studies.     

Ultrasound, Nanoparticles May Help Diabetics Avoid the Needle

November 21, 2013 11:20 am | News | Comments

A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections.           


Study IDs Possible Osteoporosis Treatment

November 21, 2013 10:07 am | News | Comments

After more than four years of investigation, researchers have discovered a promising treatment for osteoporosis, which is easily delivered in water soluble form.                         

New Brain Cancer Target May Lead to Better Drugs

November 20, 2013 1:00 pm | News | Comments

The deadliest brain cancer requires grueling treatment with bleak prospects for survival. Now, researchers have discovered a key component to how these aggressive tumors grow that could lead to better solutions.              

Princeton to Give Students Unapproved Meningitis Vaccine

November 18, 2013 4:55 pm | by GEOFF MULVIHILL - Associated Press - Associated Press | News | Comments

Princeton University officials decided Monday to make available a meningitis vaccine that hasn't been approved in the U.S. to stop the spread of the sometimes deadly disease on campus.                    

Two-step Method Promising in Pancreatic Cancer Fight

November 15, 2013 12:54 pm | News | Comments

Researchers have developed a new technique for fighting deadly and hard-to-treat pancreatic cancer that uses two different types of nanoparticles, the first type clearing a path into tumor cells for the second, which delivers chemotherapy drugs. 

Treatment Successful for Fatal Mitochondrial Defect in Mice

November 15, 2013 12:29 pm | News | Comments

The transplant anti-rejection drug rapamycin showed unexpected benefits in a mouse model of a fatal defect in the energy powerhouses of cells, the mitochondria.                            


Gut Microbes in Healthy Kids Carry Antibiotic Resistance Genes

November 14, 2013 12:25 pm | News | Comments

Friendly microbes in the intestinal tracts (guts) of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists.                      

Some Investigational Cancer Drugs Can Fuel Tumor Growth

November 12, 2013 12:01 pm | News | Comments

Researchers studying how cancer spreads into bone have made a surprising discovery that suggests several investigational anti-cancer therapies just entering the drug-development pipeline may not have the desired effect.         

Resistance to Malaria Drugs Spreading in SE Asia

November 12, 2013 3:05 am | by Matthew Pennington -- ASSOCIATED PRESS | News | Comments

U.S. experts are raising the alarm over the spread of drug-resistant malaria in several Southeast Asian countries, endangering major global gains in fighting the mosquito-borne disease that kills more than 600,000 people annually.     

New Therapeutic Target Identified for ALS, Dementia

November 11, 2013 11:44 am | News | Comments

A team of scientists have identified a novel therapeutic approach for the most frequent genetic cause of ALS, a disorder of the regions of the brain and spinal cord that control voluntary muscle movement, and frontotemporal degeneration, the second most frequent dementia.

NIH Launches Investigational Herpes Vaccine Trial

November 8, 2013 11:47 am | News | Comments

Researchers have launched an early-stage clinical trial of an investigational vaccine designed to prevent genital herpes disease.                                   

Gabapentin May Treat Alcohol Dependence

November 5, 2013 1:06 pm | News | Comments

The generic anticonvulsant medication gabapentin shows promise as an effective treatment for alcohol dependence, based on the results of a 150-patient clinical trial of the medication. The study found that alcohol dependent patients using gabapentin were more likely to stop drinking or refrain from heavy drinking than those taking placebo.

Candidate Vaccine Against RSV Developed

November 1, 2013 12:50 pm | News | Comments

An experimental vaccine to protect against respiratory syncytial virus (RSV), a leading cause of illness and hospitalization among very young children, elicited high levels of RSV-specific antibodies when tested in animals, according to a new report.

Method Can Kill Drug-resistant Cancer Cells

November 1, 2013 12:41 pm | News | Comments

Cisplatin is a chemotherapy drug given to more than half of all cancer patients. The drug kills cells very effectively, but tumors can become resistant to the drug and grow back. A new study offers a possible way to overcome that resistance.   

Bone Drug Kills Leukemia in Mice

November 1, 2013 10:00 am | by Harvard Medical School | News | Comments

A bone drug already on the market for osteoporosis may kill chronic myelogenous leukemia (CML) stem cells thought to persist in the bone marrow after standard therapy, lowering the likelihood of disease recurrence, according to a new study.

Botox Modified for Pain Treatment

October 31, 2013 2:01 pm | News | Comments

A team of scientists created and characterized a new molecule, using elements of Clostridium botulinum and Clostridium tetani neurotoxins, that was able to alleviate hypersensitivity to inflammatory pain.           

Lab-made Cholesterol Can Help Treat Heart Disease

October 30, 2013 12:08 pm | News | Comments

A new type of “good cholesterol,” made in the lab, could one day deliver drugs to where they are needed in the body to treat disease or be used in medical imaging, according to scientists.                 

HPV Strains Affecting African-American Women Differ from Vaccines

October 29, 2013 12:13 pm | News | Comments

Two subtypes of human papillomavirus (HPV) prevented by vaccines are half as likely to be found in African-American women as in white women with precancerous cervical lesions, according to researchers.              

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