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Treatment Successful for Fatal Mitochondrial Defect in Mice

November 15, 2013 12:29 pm | News | Comments

The transplant anti-rejection drug rapamycin showed unexpected benefits in a mouse model of a fatal defect in the energy powerhouses of cells, the mitochondria.                            

Gut Microbes in Healthy Kids Carry Antibiotic Resistance Genes

November 14, 2013 12:25 pm | News | Comments

Friendly microbes in the intestinal tracts (guts) of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists.                      

New Guidelines Issued for Heart Attack, Stroke Prevention

November 13, 2013 2:33 am | by MARILYNN MARCHIONE - AP Chief Medical Writer - Associated Press | News | Comments

The American Heart Association and American College of Cardiology have issued the first new guidelines in a decade for preventing heart attacks and strokes. Among other things, they call for twice as many Americans to consider taking cholesterol-lowering statin drugs.

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Some Investigational Cancer Drugs Can Fuel Tumor Growth

November 12, 2013 12:01 pm | News | Comments

Researchers studying how cancer spreads into bone have made a surprising discovery that suggests several investigational anti-cancer therapies just entering the drug-development pipeline may not have the desired effect.         

Resistance to Malaria Drugs Spreading in SE Asia

November 12, 2013 3:05 am | by Matthew Pennington -- ASSOCIATED PRESS | News | Comments

U.S. experts are raising the alarm over the spread of drug-resistant malaria in several Southeast Asian countries, endangering major global gains in fighting the mosquito-borne disease that kills more than 600,000 people annually.     

New Therapeutic Target Identified for ALS, Dementia

November 11, 2013 11:44 am | News | Comments

A team of scientists have identified a novel therapeutic approach for the most frequent genetic cause of ALS, a disorder of the regions of the brain and spinal cord that control voluntary muscle movement, and frontotemporal degeneration, the second most frequent dementia.

NIH Launches Investigational Herpes Vaccine Trial

November 8, 2013 11:47 am | News | Comments

Researchers have launched an early-stage clinical trial of an investigational vaccine designed to prevent genital herpes disease.                                   

Testosterone Treatments May Increase Heart Risks

November 5, 2013 4:15 pm | by LINDSEY TANNER - AP Medical Writer - Associated Press | News | Comments

Testosterone treatments may increase risks for heart attacks, strokes and death in older men with low hormone levels and other health problems, a big Veterans Affairs study suggests.                   

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Gabapentin May Treat Alcohol Dependence

November 5, 2013 1:06 pm | News | Comments

The generic anticonvulsant medication gabapentin shows promise as an effective treatment for alcohol dependence, based on the results of a 150-patient clinical trial of the medication. The study found that alcohol dependent patients using gabapentin were more likely to stop drinking or refrain from heavy drinking than those taking placebo.

Candidate Vaccine Against RSV Developed

November 1, 2013 12:50 pm | News | Comments

An experimental vaccine to protect against respiratory syncytial virus (RSV), a leading cause of illness and hospitalization among very young children, elicited high levels of RSV-specific antibodies when tested in animals, according to a new report.

Method Can Kill Drug-resistant Cancer Cells

November 1, 2013 12:41 pm | News | Comments

Cisplatin is a chemotherapy drug given to more than half of all cancer patients. The drug kills cells very effectively, but tumors can become resistant to the drug and grow back. A new study offers a possible way to overcome that resistance.   

Bone Drug Kills Leukemia in Mice

November 1, 2013 10:00 am | by Harvard Medical School | News | Comments

A bone drug already on the market for osteoporosis may kill chronic myelogenous leukemia (CML) stem cells thought to persist in the bone marrow after standard therapy, lowering the likelihood of disease recurrence, according to a new study.

Botox Modified for Pain Treatment

October 31, 2013 2:01 pm | News | Comments

A team of scientists created and characterized a new molecule, using elements of Clostridium botulinum and Clostridium tetani neurotoxins, that was able to alleviate hypersensitivity to inflammatory pain.           

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HIV-like Virus Suppressed in Monkeys

October 31, 2013 8:30 am | by MALCOLM RITTER - AP Science Writer - Associated Press | News | Comments

Doctors may one day be able to control a patient's HIV infection in a new way: injecting swarms of germ-fighting antibodies, two new studies suggest. In monkeys, that strategy sharply reduced blood levels of a cousin of HIV.       

Lab-made Cholesterol Can Help Treat Heart Disease

October 30, 2013 12:08 pm | News | Comments

A new type of “good cholesterol,” made in the lab, could one day deliver drugs to where they are needed in the body to treat disease or be used in medical imaging, according to scientists.                 

HPV Strains Affecting African-American Women Differ from Vaccines

October 29, 2013 12:13 pm | News | Comments

Two subtypes of human papillomavirus (HPV) prevented by vaccines are half as likely to be found in African-American women as in white women with precancerous cervical lesions, according to researchers.              

Why is There No Cure for the Common Cold?

October 29, 2013 11:48 am | Videos | Comments

In a pair of landmark studies that exploit the genetic sequencing of the “missing link” cold virus, rhinovirus C, scientists have constructed a 3-D model of the pathogen that shows why there is no cure yet for the common cold.       

Antibody Fragment Fights Alzheimer's in Mice

October 25, 2013 2:02 pm | News | Comments

Mice models of Alzheimer's treated with one abdominal injection of an antibody fragment designed by researchers showed, after only five days, improved memory and ability to learn as the result of less aggregated toxins and an increase in the number of neurons.

Lab-designed Global HIV Vaccine Promising in Monkeys

October 25, 2013 12:46 pm | News | Comments

The considerable diversity of HIV worldwide represents a critical challenge for designing an effective HIV vaccine. Now, a scientific team has shown that bioinformatically optimized HIV vaccine antigens might be useful in the design of a global HIV vaccine.

Doubling Forces to Extend Glioblastoma Survival

October 25, 2013 11:53 am | News | Comments

A novel combination of two oral targeted drugs dramatically slowed the growth of glioblastoma brain tumors in mice and significantly extended the animals’ survival, scientists report.                   

Review Highlights Side Effects of Daily Aspirin Dosage

October 24, 2013 1:57 pm | News | Comments

Researchers have published the most comprehensive review of the benefits and risks of a daily dose of prophylactic aspirin and warn that greater understanding of side effects is needed.                   

New Eye Treatment Effective in Laboratory Tests

October 23, 2013 1:01 pm | News | Comments

A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to new experiments.                    

Nanoparticles Deliver 'One-two Punch' to Aggressive Tumors

October 22, 2013 12:04 pm | News | Comments

To overcome triple negative breast cancer's eventual resistance to drugs, chemical engineers have designed nanoparticles that now only carry a cancer drug, but also carry short strands of RNA that can shut off one of the genes that cancer cells use to escape the drug.

Database of Disease Genes IDs Drug Therapies

October 15, 2013 11:37 am | News | Comments

 Researchers have created a massive online database that matches thousands of genes linked to cancer and other diseases with various drugs that target those genes.                       

New MS Treatment is Promising in Mice

October 10, 2013 11:53 am | News | Comments

Scientists have identified a set of compounds that may be used to treat MS in a new way: by boosting a population of progenitor cells that can in turn repair MS-damaged nerve fibers.                   

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