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Innovative Screening Strategy Uncovers New Drugs, Biology

December 23, 2013 11:15 am | News | Comments

Scientists at The Scripps Research Institute (TSRI) have demonstrated a drug-discovery strategy with a double payoff—it enables the rapid selection of chemical compounds that have a desired effect on cells and also highlights how the compounds work. To illustrate the power of the innovative technique, the TSRI researchers used it to identify a compound that shows promise for treating obesity-linked diabetes. Learn more...

Study IDs, Breaks Down 'Wall' Around Tumors

December 20, 2013 12:12 pm | News | Comments

Researchers have identified how the ‘wall’ around cancer tumors functions and how to break it down, enabling the body’s own defenses to reach and kill the cancer cells within.                     

One Step Closer to a 'Universal' Flu Vaccine

December 20, 2013 11:49 am | News | Comments

Researchers report promising steps toward the creation of a universal flu vaccine, one that could be produced more quickly and offer broader protection than the virus-specific inoculants available today.              

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Drug Blocks HIV in Lab, Human Tests Planned

December 19, 2013 2:51 pm | by MALCOLM RITTER - AP Science Writer - Associated Press | News | Comments

Can an experimental drug developed to treat epilepsy block the AIDS virus? A preliminary lab study suggests it's possible, and researchers are eager to try it in people.                        

Lessening X-ray Damage is Healthy for Protein Discovery

December 19, 2013 11:18 am | News | Comments

New recommendations for using X-rays promise to speed investigations aimed at understanding the structure and function of biologically important proteins– information critical to the development of new drugs.            

ALS Toxicity Reduced in Animal Models

December 17, 2013 11:10 am | News | Comments

In a new study researchers have found a way of reducing ALS disease toxicity, which slows the dysfunction of neurons and shows that a parallel mechanism can reduce toxicity in mammalian cells.                   

Vitamins Don't Block Disease, Studies Say

December 16, 2013 5:54 pm | by LAURAN NEERGAARD - AP Medical Writer - Associated Press | News | Comments

There's more disappointing news about multivitamins: Two major studies found popping the pills didn't protect aging men's brains or help heart attack survivors.                          

Antibodies Block Malaria Invasion

December 16, 2013 11:43 am | News | Comments

Scientists have discovered a key process during the invasion of the blood cell by the Malaria parasite, and more importantly, found a way to block this invasion.                          

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New Drug, Method Show Breast Cancer Promise

December 16, 2013 8:30 am | by MARILYNN MARCHIONE - AP Chief Medical Writer - Associated Press | News | Comments

A novel way to speed the testing of cancer drugs and quickly separate winners from duds has yielded its first big result: an experimental medicine that shows promise against a hard-to-treat form of breast cancer.           

Hearts of Men, Women Affected Differently by Diabetes Meds

December 13, 2013 12:51 pm | News | Comments

Widely used treatments for type 2 diabetes have different effects on the hearts of men and women, even as the drugs control blood sugar equally well in both sexes, according to new research.                   

Cure or Drug for Dementia Possible by 2025

December 12, 2013 8:30 am | by MARIA CHENG - AP Medical Writer - Associated Press | News | Comments

British Prime Minister David Cameron says he hopes to kick-start an international effort to find a cure or effective treatment for dementia by 2025.                              

New Bird Flu Strain Still Damaging After Drug-resistance

December 11, 2013 11:30 am | News | Comments

Researchers reported that a virulent new strain of influenza appears to retain its ability to cause serious disease in humans even after it develops resistance to antiviral medications.                   

Gene May Predict Human Response to Antidepressants

December 11, 2013 11:15 am | News | Comments

Researchers have discovered a gene that may reveal whether people are likely to respond well to SSRI antidepressants, both generally and in specific formulations.                           

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Gene Therapy Promising for Hemophilia

December 11, 2013 10:52 am | News | Comments

Researchers have found that a new kind of gene therapy led to a dramatic decline in bleeding events in dogs with naturally occurring hemophilia A.                             

'Bubble Boy' Disease Treated with Gene Therapy

December 9, 2013 12:44 pm | News | Comments

Researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated as part of an international clinical study of a new form of gene therapy.

Fertility Drugs Lead to Multiple Births, Not IVF

December 4, 2013 5:00 pm | by MARILYNN MARCHIONE - AP Chief Medical Writer - Associated Press | News | Comments

Triplets-and-more increasingly are the result of drugs given to women to make them produce eggs — not from using multiple embryos from IVF, or lab-dish fertilization, new research shows.                   

Restoring 'Exhausted' HIV-fighting Immune Cells

December 3, 2013 12:35 pm | News | Comments

Researchers have identified a protein that causes loss of function in immune cells combatting HIV. The scientists report that the protein, Sprouty-2, is a promising target for future HIV drug development.                 

Whooping Cough Shot Cuts Illness, Maybe Not Spread

November 26, 2013 11:39 am | by MIKE STOBBE -- AP Medical Writer | News | Comments

A government study offers a new theory on why the whooping cough vaccine doesn't seem to be working as well as expected. The research suggests that while the vaccine may keep people from getting sick, it doesn't prevent them from spreading whooping cough to others.

Killer Cocktail Fights Brain Cancer

November 25, 2013 2:53 pm | News | Comments

A novel immune-boosting drug combination eradicates glioblastoma brain cancer in mice, according to a new study.                                        

Team Creates 'Synthetic Antibodies'

November 25, 2013 12:05 pm | News | Comments

Chemical engineers have developed a novel way to generate nanoparticles that can recognize specific molecules, opening up a new approach to building durable sensors for many different compounds.                

New Link Between Obesity, Diabetes Found

November 21, 2013 12:15 pm | News | Comments

A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to new mouse studies.     

Ultrasound, Nanoparticles May Help Diabetics Avoid the Needle

November 21, 2013 11:20 am | News | Comments

A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections.           

Study IDs Possible Osteoporosis Treatment

November 21, 2013 10:07 am | News | Comments

After more than four years of investigation, researchers have discovered a promising treatment for osteoporosis, which is easily delivered in water soluble form.                         

New Brain Cancer Target May Lead to Better Drugs

November 20, 2013 1:00 pm | News | Comments

The deadliest brain cancer requires grueling treatment with bleak prospects for survival. Now, researchers have discovered a key component to how these aggressive tumors grow that could lead to better solutions.              

Princeton to Give Students Unapproved Meningitis Vaccine

November 18, 2013 4:55 pm | by GEOFF MULVIHILL - Associated Press - Associated Press | News | Comments

Princeton University officials decided Monday to make available a meningitis vaccine that hasn't been approved in the U.S. to stop the spread of the sometimes deadly disease on campus.                    

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