Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. A team of researchers has now hijacked that delivery system for a different purpose: administering cancer drugs.
Hope for healthier airways may be on the horizon thanks to a human airway muscle-on-a-chip that could be used to test new drugs because it accurately mimics the way smooth muscle contracts in the human airway, under normal circumstances and when exposed to asthma triggers.
Signaling the seriousness of the threat posed by antibiotic-resistant germs, President Barack Obama on Thursday ordered the government to create a national plan to fight them by early 2015.
A treatment regimen is safe and effective for restoring skin pigmentation in vitiligo patients, according to a new study. Patients were randomly divided into two study groups: Group A received a combination therapy; Group B received only NB UVB treatment.
An anti-addiction drug used to fight the nation's heroin and painkiller abuse epidemics poses a threat to young children who accidentally swallow relatives' prescriptions, a federal study says. Some children have died.
On this episode of Bioscience Technology This Week, Christina Jakubowski explores the role that bees may play in the search for antibiotic alternatives. Our second story focuses on how increased carbon dioxide levels in water can rob sharks of their ability to sense the smell of food.
One of the most rapidly fast-tracked vaccines in history— an anti-Ebola “ChAd3” vaccine— just started clinical trial in humans, and may be done as soon as November. But a second fast-tracked anti-Ebola vaccine— called an “rVSV” vaccine— is hot on its heels.
Mice treated with antibiotics to remove most of their intestinal bacteria or raised under sterile conditions have impaired antibody responses to seasonal influenza vaccination, researchers have found.
A research team is looking at whether an antibiotic has the potential to prevent or treat irregular heartbeats brought on by other medicines, thanks to a grant from national charity in the UK.
Taking benzodiazepines (widely prescribed drugs to treat anxiety and insomnia) is associated with an increased risk of developing Alzheimer's disease, particularly for long-term users, suggests a new study.
Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases.
ZMapp, an experimental drug that may have already have saved a few patients in Africa, is the most effective anti-Ebola therapy yet, according to a recent Nature paper on rhesus macaques monkeys.
A pharmacist who oversaw the sterile clean rooms at a Massachusetts compounding pharmacy responsible for a deadly meningitis outbreak was arrested Thursday as he was about to board a flight for Hong Kong, federal officials said.
Federal researchers next week will start testing humans with an experimental vaccine to prevent the deadly Ebola virus. The NIH announced today that it is launching the safety trial on a vaccine developed by the agency's National Institute of Allergy and Infectious Diseases and GSK.
The federal government is finalizing new restrictions on hundreds of medicines containing hydrocodone, the highly addictive painkiller that has grown into the most widely prescribed drug in the U.S.
New research suggests a one-two punch could help battle polio in some of the world's most remote and strife-torn regions: Giving a single vaccine shot to children who've already swallowed drops of an oral polio vaccine greatly boosted their immunity.
As anyone who has bitten into a chili pepper knows, its burning spiciness— though irresistible to some — is intolerable to others. Scientists exploring the chili pepper’s effect are using their findings to develop a new drug candidate for many kinds of pain.
New research found that receiving antibiotic treatments early in life can increase susceptibility to specific diseases later on. The study helps scientists understand how different antibiotics affect good bacteria.
A new study suggests that antibiotic exposure during a critical window of early development disrupts the bacterial landscape of the gut, home to trillions of diverse microbes, and permanently reprograms the body’s metabolism, setting up a predisposition to obesity.
It's an eye-catching angle in the story of an experimental treatment for Ebola: The drug comes from tobacco plants that were turned into living pharmaceutical factories. Using plants this way — sometimes called "pharming" — can produce complex and valuable proteins for medicines.
An Iowa drug developer says it has enough doses of a possible vaccine for the deadly Ebola virus to launch an initial round of human testing. NewLink Genetics Chief Financial Officer Gordon Link says the timing of the trials is uncertain, but the company is receiving help from a number of sources to speed up the process.
A Spanish missionary priest being treated for Ebola died Tuesday in a Madrid hospital amid a worldwide debate over who should get experimental Ebola treatments. After holding a teleconference with medical experts around the world, the WHO declared it is ethical to use unproven Ebola drugs and vaccines in the current outbreak.
There have been stunning “firsts” in research on idiopathic pulmonary fibrosis (IPF), a mysterious disease that stiffens and stills the lungs, killing half its victims in three years. In May, results of Phase 3 clinical trials on the first two effective drugs for IPF were published in the New England Journal of Medicine (NEJM). And in June, the first paper explaining IPF was published in Science Translational Medicine.
A large-scale University-led study involving more than 180,000 people shows that patients treated with a drug widely prescribed for type 2 diabetes can live longer than people without the condition. The findings indicate that a drug known as metformin, used to control glucose levels in the body and already known to exhibit anticancer properties, could offer prognostic and prophylactic benefits to people without diabetes.
In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers report that they have identified a possible new drug target for treating the disease.