Obese adolescents not getting enough sleep? A new study shows they could be increasing their risk for developing diabetes, heart disease and stroke. Lack of sleep and obesity have been associated with an increased risk of cardiovascular and metabolic diseases in adults and young children. However, the association is not as clear in adolescents.
In a new study that could help doctors extend the lives of patients awaiting liver transplants,...
A team of researchers identified mutations in a gene that can reduce the risk of developing type...
In two new studies, the so-called “obesity hormone” leptin and hormones used for birth control...
New research from Uppsala University shows that saturated fat builds more fat and less muscle than polyunsaturated fat. This is the first study on humans to show that the fat composition of food not only influences cholesterol levels in the blood and the risk of cardiovascular disease but also determines where the fat will be stored in the body.
Researchers exploring a possible link between metabolic defects and seizures have determined that diet could influence susceptibility to seizures, and they have identified a common diabetes drug that could be a useful treatment.
People living in cold, northern latitudes have bacteria in their guts that may predispose them to obesity, according to a new study. The researchers’ analysis of the gut microbes of more than a thousand people from around the world showed that those living in northern latitudes had more gut bacteria that have been linked to obesity than did people living farther south.
Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice. Their findings, they report, may help develop drugs to decrease excessive fat production and its associated conditions in people, including fatty liver disease and diabetes.
A cure for type 1 diabetes has long eluded even the top experts. Not because they do not know what must be done—but because the tools did not exist to do it. But now scientists in the laboratory of Gladstone Institutes’ Investigator Sheng Ding, MD, PhD, harnessing the power of regenerative medicine, have developed a technique in animal models that could replenish the very cells destroyed by the disease.
Johns Hopkins researchers have discovered that valproic acid, a widely prescribed drug for treating epilepsy, has the additional benefits of reducing fat accumulation in the liver and lowering blood sugar levels in the blood of obese mice.
We’ve all heard about circadian rhythm, the roughly 24-hour oscillations of biological processes that occur in many living organisms. Yet for all its influence in many aspects of our lives—from sleep to immunity and, particularly, metabolism—relatively little is understood about the mammalian circadian rhythm and the interlocking processes that comprise this complex biological clock.
New Molecule Protects the Brain from Detrimental Effects Associated with Diabetes and High Blood SugarJanuary 29, 2014 1:12 pm | News | Comments
Researchers from the Hebrew University of Jerusalem have found a potential neuro-inflammatory pathway that could be responsible for the increases of diabetics’ risk of Alzheimer's and dementia. They also reveal a potential treatment to reverse this process.
The Wnt/β-catenin signaling pathway and microRNA 335 are instrumental in helping form differentiated progenitor cells from stem cells. These are organized in germ layers and are thus the origin of different tissue types, including the pancreas and its insulin-producing beta cells.
Google unveiled a contact lens that monitors glucose levels in tears, a potential reprieve for millions of diabetics who have to jab their fingers to draw their own blood as many as 10 times a day. The prototype, which Google says will take at least five years to reach consumers, is one of several medical devices being designed by companies to make glucose monitoring for diabetic patients more convenient.
The controversial notion that being overweight might actually be healthier for some people with diabetes — seems to be a myth, researchers report. A major study finds there's no survival advantage to being large, and a disadvantage to being very large.
A single molecule, which acts equally on the receptors of the metabolic hormones glucagon and glucagon-like peptide-1 (GLP-1) improves body weight and diabetes through restored function of the anti-obesity hormone leptin. Scientists found out that treatment of obese mice with this GLP-1/Glucagon co-agonist improves metabolism and body weight associated with restored function of the weight lowering hormone leptin.
High concentrations of serum long-chain omega-3 fatty acids may help reduce the risk of type 2 diabetes, according to a University of Eastern Finland study. The sources of these fatty acids are fish and fish oils. The Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) determined the serum omega-3 fatty acid concentrations of 2,212 men between 42 and 60 years of age at the onset of the study, in 1984–1989.
Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study. DNA sequences that don’t encode proteins were once dismissed as “junk DNA”, but scientists are increasingly discovering that some regions are important for controlling which genes are switched on.
Researchers have mapped genetic variations associated with an increased risk of multiple sclerosis (MS) and myasthenia gravis (MG), bringing science one step closer to understanding these serious autoimmune disorders.
A new neuroscience study sheds light on the biological underpinnings of obesity. The in vivo study reveals how a protein in the brain helps regulate food intake and body weight.
New research has revealed two new genetic causes of neonatal diabetes. The study provides further insights on how the insulin-producing beta cells are formed in the pancreas.
Researchers have found that dysfunction in a single gene in mice causes fasting hyperglycemia, one of the major symptoms of type 2 diabetes.
Metabolism was lost in the shadows of cancer research for decades but has recently been reclaiming some of the spotlight. Now, research has shown that aerobic glycolysis is not the consequence of the cancerous activity of malignant cells but is itself a cancerous event.
Widely used treatments for type 2 diabetes have different effects on the hearts of men and women, even as the drugs control blood sugar equally well in both sexes, according to new research.
Researchers have uncovered a genetic deficiency in males that can trigger the development of one of the most common types of liver cancer and forms of diabetes.
Researchers have shown that they can grow unlimited quantities of intestinal stem cells, then stimulate them to develop into nearly pure populations of different types of mature intestinal cells.
Chemical engineers have developed a novel way to generate nanoparticles that can recognize specific molecules, opening up a new approach to building durable sensors for many different compounds.
A single overactive enzyme worsens the two core defects of diabetes—impaired insulin sensitivity and overproduction of glucose—suggesting that a drug targeting the enzyme could help correct both at once, according to new mouse studies.
A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections.
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