Aging of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study. The finding provides a new molecular mechanism underlying age-related impairment of insulin-producing cells and diabetes.
The number of American men and women with big-bellied, apple-shaped figures — the most dangerous...
Researchers have identified nine genetic variants that dramatically increase the risk of...
People who are obese may be more susceptible to environmental food cues than their lean counterparts due to differences in brain chemistry that make eating more habitual and less rewarding, according to a new study.
People can become addicted to eating for its own sake but not to consuming specific foods such as those high in sugar or fat, new research suggests. An international team of scientists has found no strong evidence for people being addicted to the chemical substances in certain foods.
A meta-analysis comprising 16 studies and 891,426 participants from various regions of the world shows that prediabetes increases the risk of cancer by 15 percent, with differing risks depending on the type of cancer.
A spinach extract containing green leaf membranes called thylakoids decreases hedonic hunger with up to 95 percent and increases weight loss by 43 percent, according to a new study.
On this episode of Bioscience Technology This Week, Christina Jakubowski highlights the link between mid-life obesity and an increased dementia risk later in life. Our second story focuses on researchers who are sequencing salamander genomes.
Scientists have demonstrated the effectiveness of a fiber-based dietary ingredient that makes people feel less hungry and consume less food. Tthe new product consists of a combination of dietary fiber sources including a viscous hydrocolloid and a whole-grain corn flour rich in resistant starch.
Researchers have developed a way to use a laser to measure people's blood sugar, and, with more work to shrink the laser system to a portable size, the technique could allow diabetics to check their condition without pricking themselves to draw blood.
New work by scientists suggests that both major forms of diabetes, type 1 and type 2, are the result of the same mechanism - the formation of toxic clumps of a hormone called amylin.
It sounds like science fiction, but it seems that bacteria within us– which outnumber our own cells about 100-fold– may very well be affecting both our cravings and moods to get us to eat what they want, and often are driving us toward obesity.
A new study suggests that antibiotic exposure during a critical window of early development disrupts the bacterial landscape of the gut, home to trillions of diverse microbes, and permanently reprograms the body’s metabolism, setting up a predisposition to obesity.
An enzyme called 12-LO promotes the obesity-induced oxidative stress in the pancreatic cells that leads to pre-diabetes, and diabetes. 12-LO’s enzymatic action is the last step in the production of certain small molecules that harm the cell, according to a team from Indiana University School of Medicine. The findings will enable the development of drugs that can interfere with this enzyme, preventing or even reversing diabetes.
In this episode of Bioscience Technology This Week, Rob Fee discusses how studying fruit flies could revolutionize diabetes research. Our second story focuses on how venom could form the basis of a new class of cancerfighting drugs.
A large-scale University-led study involving more than 180,000 people shows that patients treated with a drug widely prescribed for type 2 diabetes can live longer than people without the condition. The findings indicate that a drug known as metformin, used to control glucose levels in the body and already known to exhibit anticancer properties, could offer prognostic and prophylactic benefits to people without diabetes.
A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment.
The relationship between saturated fat and type 2 diabetes may be more complex than previously thought, according a study that claims saturated fatty acids can be associated with both an increased and decreased risk of developing the disease, depending on the type of fatty acids present in the blood.
A new study has found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type 1 diabetes-insulin-producing beta cells.
Much of the liver’s metabolic function is governed by circadian rhythms—our own body clock—and UC Irvine researchers have now found two independent mechanisms by which this occurs. The study reveals new information about the body clock’s sway over metabolism and points the way to more focused drug treatments for liver disease and such metabolic disorders as obesity and diabetes.
Exposure of pregnant mice to the pesticide DDT is linked to an increased risk of obesity, diabetes, high cholesterol, and related conditions in female offspring later in life, according to a study led by the University of California, Davis.
Young adults who were breastfed for three months or more as babies have a significantly lower risk of chronic inflammation associated with cardiovascular and metabolic diseases, according to research from the Brown School at Washington University in St. Louis.
A new study has found that turning the thermostat down a few notches at night may expand brown fat tissue mass and activity, which could lead to metabolic benefits such as more effective disposal of glucose.
The popular culinary herbs oregano and rosemary are packed with healthful compounds, and now lab tests show they could work in much the same way as prescription anti-diabetic medication, scientists report. In their new study, they found that how the herbs are grown makes a difference, and they also identified which compounds contribute the most to this promising trait.
People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells. Now, a team of researchers may have found a solution in autophagy, a process that clears damaged and toxic proteins from cell.
A probiotic that prevents obesity could be on the horizon. Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, Vanderbilt University investigators have discovered.
In mice with diet-induced diabetes, the equivalent of type 2 diabetes in humans, a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days, according to a new study.
Adults with extreme obesity have increased risks of dying at a young age from cancer and many other causes including heart disease, stroke, diabetes, and kidney and liver diseases, according to results of a new analysis.
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