On this episode of Bioscience Technology This Week, Christina Jakubowski highlights the link between mid-life obesity and an increased dementia risk later in life. Our second story focuses on researchers who are sequencing salamander genomes.
Scientists have demonstrated the effectiveness of a fiber-based dietary ingredient that makes...
Researchers have developed a way to use a laser to measure people's blood sugar, and, with more...
New work by scientists suggests that both major forms of diabetes, type 1 and type 2, are the...
It sounds like science fiction, but it seems that bacteria within us– which outnumber our own cells about 100-fold– may very well be affecting both our cravings and moods to get us to eat what they want, and often are driving us toward obesity.
A new study suggests that antibiotic exposure during a critical window of early development disrupts the bacterial landscape of the gut, home to trillions of diverse microbes, and permanently reprograms the body’s metabolism, setting up a predisposition to obesity.
An enzyme called 12-LO promotes the obesity-induced oxidative stress in the pancreatic cells that leads to pre-diabetes, and diabetes. 12-LO’s enzymatic action is the last step in the production of certain small molecules that harm the cell, according to a team from Indiana University School of Medicine. The findings will enable the development of drugs that can interfere with this enzyme, preventing or even reversing diabetes.
In this episode of Bioscience Technology This Week, Rob Fee discusses how studying fruit flies could revolutionize diabetes research. Our second story focuses on how venom could form the basis of a new class of cancerfighting drugs.
A large-scale University-led study involving more than 180,000 people shows that patients treated with a drug widely prescribed for type 2 diabetes can live longer than people without the condition. The findings indicate that a drug known as metformin, used to control glucose levels in the body and already known to exhibit anticancer properties, could offer prognostic and prophylactic benefits to people without diabetes.
A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment.
The relationship between saturated fat and type 2 diabetes may be more complex than previously thought, according a study that claims saturated fatty acids can be associated with both an increased and decreased risk of developing the disease, depending on the type of fatty acids present in the blood.
A new study has found that a peptide called caerulein can convert existing cells in the pancreas into those cells destroyed in type 1 diabetes-insulin-producing beta cells.
Much of the liver’s metabolic function is governed by circadian rhythms—our own body clock—and UC Irvine researchers have now found two independent mechanisms by which this occurs. The study reveals new information about the body clock’s sway over metabolism and points the way to more focused drug treatments for liver disease and such metabolic disorders as obesity and diabetes.
Exposure of pregnant mice to the pesticide DDT is linked to an increased risk of obesity, diabetes, high cholesterol, and related conditions in female offspring later in life, according to a study led by the University of California, Davis.
Young adults who were breastfed for three months or more as babies have a significantly lower risk of chronic inflammation associated with cardiovascular and metabolic diseases, according to research from the Brown School at Washington University in St. Louis.
A new study has found that turning the thermostat down a few notches at night may expand brown fat tissue mass and activity, which could lead to metabolic benefits such as more effective disposal of glucose.
The popular culinary herbs oregano and rosemary are packed with healthful compounds, and now lab tests show they could work in much the same way as prescription anti-diabetic medication, scientists report. In their new study, they found that how the herbs are grown makes a difference, and they also identified which compounds contribute the most to this promising trait.
People with Type 2 diabetes have an excess of a protein called islet amyloid polypeptide, or IAPP, and the accumulation of this protein is linked to the loss of insulin-producing pancreatic beta cells. Now, a team of researchers may have found a solution in autophagy, a process that clears damaged and toxic proteins from cell.
A probiotic that prevents obesity could be on the horizon. Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, Vanderbilt University investigators have discovered.
In mice with diet-induced diabetes, the equivalent of type 2 diabetes in humans, a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days, according to a new study.
Adults with extreme obesity have increased risks of dying at a young age from cancer and many other causes including heart disease, stroke, diabetes, and kidney and liver diseases, according to results of a new analysis.
Scientists have identified a set of 10 proteins in the blood which can predict the onset of Alzheimer’s, marking a significant step towards developing a blood test for the disease.
Scientists have discovered that obese individuals lack a protein that is essential for regulating blood glucose levels, causing them to face higher risks of developing diabetes.
By switching off a single gene, scientists have converted human gastrointestinal cells into insulin-producing cells, demonstrating in principle that a drug could retrain cells inside a person's GI tract to produce insulin.
A piece of detective work has mapped a special gene variant among Greenlanders that plays a particularly important role in the development of type 2 diabetes. The results can be used to improve prevention and treatment options for those genetically at-risk.
Researchers, tackling a modern challenge of diabetes research, have identified a gene believed to disrupt the ability of beta cells to produce insulin resulting in type 1 diabetes. The loss of beta cell function may be driven by a defect in Clec16a, a gene responsible for getting rid of old mitochondria, and making room for fresh ones. Healthy mitochondria are crucial to allowing beta cells to produce insulin and control blood sugar levels.
Scientists have made big progress on a "bionic pancreas" to free some people with diabetes from the daily ordeal of managing their disease. A wearable, experimental device passed a real-world test, constantly monitoring blood sugar and automatically giving insulin or a sugar-boosting drug as eeded, doctors said.
An imbalance of female sex hormones among men in Western nations may be contributing to high levels of male obesity, according to new research. The study suggest that obesity among Western men could be linked with exposure to substances containing the female sex hormone estrogen.
The gluten-specific enzyme ALV003 reduces exposure to gluten and gluten’s potential harm in individuals suffering who have celiac disease, according to a new study.
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