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Researchers Solve Metabolic Mystery Lending Insight into Lafora Disease

January 26, 2015 9:32 am | by Elizabeth Adams, University of Kentucky | News | Comments

Scientists have determined how an enzyme essential for energy metabolism functions.                              

How the Immune System Promotes Digestive Health

January 22, 2015 4:11 pm | by University of Utah | News | Comments

It involves fostering a community of "good" gut bacteria.      ...

Could Our Brains Instruct Our Bodies to Burn More Fat?

January 20, 2015 10:14 am | by Monash University | News | Comments

By uncovering the action of two naturally occurring hormones, scientists may have...

FDA Approves First-of-Kind Device to Treat Obesity

January 15, 2015 9:51 am | by FDA | News | Comments

The U.S. Food and Drug Administration today approved the Maestro Rechargeable System for certain...

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Studying Fetal Liver Fibrogenesis

January 14, 2015 4:07 pm | by Sarah Plumridge, Northwestern University | News | Comments

Fibrosis is a constant feature of all chronic liver diseases.                                 

One-Size-Fits-All Approach Can Lead to Diabetes Over-Treatment

January 13, 2015 10:30 am | by Yale | News | Comments

Diabetes treatments have saved many lives, but in older patients with multiple medical conditions, aggressively controlling blood sugar with insulin and sulfonylurea drugs, could lead to over-treatment and hypoglycemia (low blood sugar), according to new research by Yale School of Medicine researchers.                          

Hacking Fat Cells' Metabolism Does Not Affect Insulin Resistance

January 12, 2015 9:26 am | by Johns Hopkins University | News | Comments

In the race to find a safe and effective weight loss drug, much attention has focused on the chemical processes that store and use energy.                     

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Biogen Idec, Columbia to Conduct Collaborative Genetics Research

January 12, 2015 8:48 am | by Columbia University | News | Comments

The agreement will integrate genomics research conducted at Columbia with Biogen Idec’s understanding of disease mechanisms and pathways, and expertise in discovering new medicines.             

Research Findings Have Implications for Regenerating Damaged Nerve Cells

January 7, 2015 4:07 pm | by University of Colorado, Boulder | News | Comments

Two new studies have identified a unique molecule that not only gobbles up bad cells, but also has the ability to repair damaged nerve cells.                    

Nestlé Health Science Invests $65M in Microbiome Therapy Startup

January 6, 2015 12:01 pm | News | Comments

The investment made by Nestle Health Science, a subsidiary of Nestle, will help fund the next stage of development for the startup's CDI treatment.                   

Fructose More Toxic Than Table Sugar in Mice

January 5, 2015 4:34 pm | by University of Utah | News | Comments

The fructose-glucose mixture found in high-fructose corn syrup was more toxic to mice than sucrose or table sugar.                       

Study IDs Risk Factors Linking Low Birthweight to Diabetes

January 5, 2015 4:27 pm | by Brown University | News | Comments

Studies consistently show that people born weighing 6 pounds or less face an increased risk for type 2 diabetes as adults.                       

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New Diet Pill Tricks the Body into Losing Weight

January 5, 2015 4:05 pm | by Salk Institute for Biological Studies | News | Comments

Researchers have developed an entirely new type of pill that tricks the body into thinking it has consumed calories, causing it to burn fat.                    

Year Born May Determine Obesity Risk

December 30, 2014 2:52 pm | by Sue McGreevy, Harvard University | News | Comments

Investigators working to unravel the impact of genetics versus environment on traits such as obesity may also need to consider a new factor: when individuals were born.                

Molecular Mechanism Behind Health Benefits of Dietary Restriction Identified

December 26, 2014 9:36 am | by Harvard School of Public Health | News | Comments

A new study led by Harvard School of Public Health (HSPH) researchers identifies a key molecular mechanism behind the health benefits of dietary restriction, or reduced food intake without malnutrition. Also known as calorie restriction, dietary restriction is best known for its ability to slow aging in laboratory animals.

Bacteria in Gut May Depend More on Diet than Genes

December 22, 2014 10:49 am | News | Comments

Genes are important, but diet may be even more important in determining the relative abundance of the hundreds of health-shaping bacterial species comprising an individual’s gut microbiota, according to UC San Francisco scientists whose latest mouse experiments to probe this nature-versus-nurture balance were published online in Cell Host and Microbe.

UCLA to Help Biologists, Doctors Mine 'Big Data'

December 19, 2014 9:45 am | by Eryn Brown, UCLA | News | Comments

Millions upon millions of medical records and test results. Countless DNA sequences. Hard drives stuffed with images of all kinds - pictures of cells, scans of body parts. It's all part of the deluge of information often known as "big data," an ever-growing stockpile of digital material that scientists hope will reveal insights about biology and lead to improvements in medical care.  

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Stem Cells Faulty in Duchenne Muscular Dystrophy

December 17, 2014 4:03 pm | by Stanford University | News | Comments

Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive muscle degeneration and accumulate connective tissue as they age. Now, researchers at the Stanford University School of Medicine have found that the fault may lie at least partly in the stem cells that surround the muscle fibers.

Discovery May Explain Why We Gain Weight

December 12, 2014 8:57 am | News | Comments

Researchers believe they’re on track to solve the mystery of weight gain – and it has nothing to do with indulging in holiday eggnog. They discovered that a protein, Thy1, has a fundamental role in controlling whether a primitive cell decides to become a fat cell, making Thy1 a possible therapeutic target.

A Pill to Shed Fat?

December 9, 2014 8:30 am | News | Comments

Researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of obesity, though that shift, of course, would not provide all of the many benefits of exercise.         

‘Satiety Hormone’ Leptin Links Obesity to High Blood Pressure

December 5, 2014 1:42 pm | News | Comments

Leptin, a hormone that regulates the amount of fat stored in the body, also drives the increase in blood pressure that occurs with weight gain, according to researchers.                        

Mediterranean Diet Has Marked Impact on Aging

December 3, 2014 3:42 pm | by Brigham and Women’s Hospital | News | Comments

The  Mediterranean diet consistently has been linked with an array of health benefits, including decreased risk of chronic disease and cancer. Until now, however, no studies had associated the diet with longer telomeres, one of the biomarkers of aging. Read more...

In Healthy Gut, Microbes Wax, Wane Throughout Day

December 3, 2014 10:57 am | News | Comments

Taking a single snapshot of all the bacteria that live in a mouse’s–or person’s–stomach and intestines can capture the health of the organism’s digestive system and even their risk of developing immune diseases and cancers. But it might take more than one snapshot to get a full picture, Salk researchers have discovered. Read more...

Another Case Against the Midnight Snack

December 3, 2014 10:49 am | News | Comments

These days, with the abundance of artificial light, TV, tablets and smartphones, adults and children alike are burning the midnight oil. What they are not burning is calories: with later bedtimes comes the tendency to eat. Read more...                                 

New FDA Rules Will Put Calorie Counts on Menus

November 25, 2014 1:00 pm | by Mary Clare Jalonick - Associated Press - Associated Press | News | Comments

Whether they want to or not, consumers will soon know how many calories they are eating when ordering off the menu at chain restaurants, picking up prepared foods at supermarkets and even eating a tub of popcorn at the movie theater.     

Cellular Origin of Fibrosis

November 21, 2014 10:00 am | News | Comments

Harvard Stem Cell Institute scientists at Brigham and Women’s Hospital say they have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions. Read more...

Unwinding the Mysteries of the Cellular Clock

November 21, 2014 9:54 am | News | Comments

Human existence is basically circadian. Most of us wake in the morning, sleep in the evening, and eat in between. Body temperature, metabolism, and hormone levels all fluctuate throughout the day, and it is increasingly clear that disruption of those cycles can lead to metabolic disease. Read more...

Study: Obesity Fuels Silent Heart Damage

November 21, 2014 9:27 am | News | Comments

Using an ultrasensitive blood test to detect the presence of a protein that heralds heart muscle injury, researchers from Johns Hopkins and elsewhere have found that obese people without overt heart disease experience silent cardiac damage that fuels their risk for heart failure down the road. Read more...      

Protein Linked to Aging May Be New Diabetes Target

November 6, 2014 1:38 pm | News | Comments

Researchers have identified a small protein with a big role in lowering plasma glucose and increasing insulin sensitivity. The report indicates that Sestrin 3 plays a critical role in regulating molecular pathways that control the production of glucose and insulin sensitivity in the liver.

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