Scientists have determined how an enzyme essential for energy metabolism functions.
It involves fostering a community of "good" gut bacteria. ...
By uncovering the action of two naturally occurring hormones, scientists may have...
The U.S. Food and Drug Administration today approved the Maestro Rechargeable System for certain...
Fibrosis is a constant feature of all chronic liver diseases.
Diabetes treatments have saved many lives, but in older patients with multiple medical conditions, aggressively controlling blood sugar with insulin and sulfonylurea drugs, could lead to over-treatment and hypoglycemia (low blood sugar), according to new research by Yale School of Medicine researchers.
In the race to find a safe and effective weight loss drug, much attention has focused on the chemical processes that store and use energy.
The agreement will integrate genomics research conducted at Columbia with Biogen Idec’s understanding of disease mechanisms and pathways, and expertise in discovering new medicines.
Two new studies have identified a unique molecule that not only gobbles up bad cells, but also has the ability to repair damaged nerve cells.
The investment made by Nestle Health Science, a subsidiary of Nestle, will help fund the next stage of development for the startup's CDI treatment.
The fructose-glucose mixture found in high-fructose corn syrup was more toxic to mice than sucrose or table sugar.
Studies consistently show that people born weighing 6 pounds or less face an increased risk for type 2 diabetes as adults.
Researchers have developed an entirely new type of pill that tricks the body into thinking it has consumed calories, causing it to burn fat.
Investigators working to unravel the impact of genetics versus environment on traits such as obesity may also need to consider a new factor: when individuals were born.
A new study led by Harvard School of Public Health (HSPH) researchers identifies a key molecular mechanism behind the health benefits of dietary restriction, or reduced food intake without malnutrition. Also known as calorie restriction, dietary restriction is best known for its ability to slow aging in laboratory animals.
Genes are important, but diet may be even more important in determining the relative abundance of the hundreds of health-shaping bacterial species comprising an individual’s gut microbiota, according to UC San Francisco scientists whose latest mouse experiments to probe this nature-versus-nurture balance were published online in Cell Host and Microbe.
Millions upon millions of medical records and test results. Countless DNA sequences. Hard drives stuffed with images of all kinds - pictures of cells, scans of body parts. It's all part of the deluge of information often known as "big data," an ever-growing stockpile of digital material that scientists hope will reveal insights about biology and lead to improvements in medical care.
Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive muscle degeneration and accumulate connective tissue as they age. Now, researchers at the Stanford University School of Medicine have found that the fault may lie at least partly in the stem cells that surround the muscle fibers.
Researchers believe they’re on track to solve the mystery of weight gain – and it has nothing to do with indulging in holiday eggnog. They discovered that a protein, Thy1, has a fundamental role in controlling whether a primitive cell decides to become a fat cell, making Thy1 a possible therapeutic target.
Researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of obesity, though that shift, of course, would not provide all of the many benefits of exercise.
Leptin, a hormone that regulates the amount of fat stored in the body, also drives the increase in blood pressure that occurs with weight gain, according to researchers.
The Mediterranean diet consistently has been linked with an array of health benefits, including decreased risk of chronic disease and cancer. Until now, however, no studies had associated the diet with longer telomeres, one of the biomarkers of aging. Read more...
Taking a single snapshot of all the bacteria that live in a mouse’s–or person’s–stomach and intestines can capture the health of the organism’s digestive system and even their risk of developing immune diseases and cancers. But it might take more than one snapshot to get a full picture, Salk researchers have discovered. Read more...
These days, with the abundance of artificial light, TV, tablets and smartphones, adults and children alike are burning the midnight oil. What they are not burning is calories: with later bedtimes comes the tendency to eat. Read more...
Whether they want to or not, consumers will soon know how many calories they are eating when ordering off the menu at chain restaurants, picking up prepared foods at supermarkets and even eating a tub of popcorn at the movie theater.
Harvard Stem Cell Institute scientists at Brigham and Women’s Hospital say they have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions. Read more...
Human existence is basically circadian. Most of us wake in the morning, sleep in the evening, and eat in between. Body temperature, metabolism, and hormone levels all fluctuate throughout the day, and it is increasingly clear that disruption of those cycles can lead to metabolic disease. Read more...
Using an ultrasensitive blood test to detect the presence of a protein that heralds heart muscle injury, researchers from Johns Hopkins and elsewhere have found that obese people without overt heart disease experience silent cardiac damage that fuels their risk for heart failure down the road. Read more...
Researchers have identified a small protein with a big role in lowering plasma glucose and increasing insulin sensitivity. The report indicates that Sestrin 3 plays a critical role in regulating molecular pathways that control the production of glucose and insulin sensitivity in the liver.
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