Cloning pioneer Teru Wakayama found two STAP stem cell batches made for recent Nature STAP papers were apparently not derived from a 129 mouse strain, as he was told, but F1 and B6 strains. While the erroneous data, which appeared in one of the papers, does not affect the works' main thrust, it is spurring calls for reviews of other STAP stem cell sources.
Nature has rejected the paper of a top Hong Kong researcher whose lab several times...
When a cell is exposed to dangerous environmental conditions such as high temperatures or toxic...
University of Adelaide research has shown for the first time that grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as reducing the chemotherapy's side effects. The researchers say that combining grape seed extracts with chemotherapy has potential as a new approach for bowel cancer treatment - to both reduce intestinal damage commonly caused by cancer chemotherapy and to enhance its effect.
Immune cells undergo ‘spontaneous’ changes on a daily basis that could lead to cancers if not for the diligent surveillance of our immune system, scientists have found. The research team from the Walter and Eliza Hall Institute found that the immune system was responsible for eliminating potentially cancerous immune B cells in their early stages, before they developed into B-cell lymphomas (also known as non-Hodgkin’s lymphomas).
In many people with autism and other neurodevelopmental disorders, different parts of the brain don’t talk to each other very well. Scientists have now identified, for the first time, a way in which this decreased functional connectivity can come about.
The structure of the human brain is complex, reminiscent of a circuit diagram with countless connections. But what role does this architecture play in the functioning of the brain? To answer this question, researchers have for the first time analyzed 1.6 billion connections within the brain simultaneously.
High concentrations of serum long-chain omega-3 fatty acids may help reduce the risk of type 2 diabetes, according to a University of Eastern Finland study. The sources of these fatty acids are fish and fish oils. The Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) determined the serum omega-3 fatty acid concentrations of 2,212 men between 42 and 60 years of age at the onset of the study, in 1984–1989.
Nine women in Sweden have successfully received transplanted wombs donated from relatives and will soon try to become pregnant, the doctor in charge of the pioneering project has revealed. The women were born without a uterus or had it removed because of cervical cancer. Most are in their 30s and are part of the first major experiment to test whether it's possible to transplant wombs into women so they can give birth to their own children.
British biochemist Frederick Sanger, who twice won the Nobel Prize in chemistry and was a pioneer of genome sequencing, has died at the age of 95. His death was confirmed Wednesday by the MRC Laboratory of Molecular Biology - which Sanger helped found.
Roche announced plans to invest 800 million Swiss francs within its global manufacturing network to increase production capabilities for its biologic medicines over the next five years. The investment will be spread across sites in Penzberg (Germany), Basel (Switzerland), as well as Vacaville and Oceanside (USA). Approximately 500 new jobs are expected to be created in conjunction with the facility expansions.
Three U.S.-based scientists won this year's Nobel Prize in chemistry on Wednesday for developing powerful computer models that researchers use to understand complex chemical interactions and create new drugs.
International research with participation of Danish investigators from University of Copenhagen shows that one in four Danes has serious problems with the trillion of bacteria living in their intestines. The problems appear to be associated with increased risk of obesity and diabetes.
The first clinical trial of revolutionary stem cells that won a Nobel Prize for their developer has been greenlit. The cells, called induced pluripotent stem (iPS) Cells, will be morphed into retinal cells, then given to six patients with a major cause of blindness: age-related macular degeneration (AMD).
Two years after Japan’s nuclear plant disaster, an international team of experts said that residents of areas hit by the highest doses of radiation face an increased cancer risk so small it probably won’t be detectable. In fact, experts calculated that increase at about 1 extra percentage point added to a Japanese infant’s lifetime cancer risk.
Artificial bone, created using stem cells and a new lightweight plastic, could soon be used to heal shattered limbs. The use of bone stem cells combined with a degradable rigid material that inserts into broken bones and encourages real bone to re-grow has been developed at the Universities of Edinburgh and Southampton.
How, when and where a pathogen is transmitted between two individuals in a population is crucial in understanding and predicting how a disease will spread. New research has laid the foundation for a new generation of zoonotic disease spreading models, which could allow for more targeted prevention strategies.
Dendritic cells perform a vital role for the immune system: They engulf pathogens, break them down into their component parts, and then display the pieces on their surface. In order to do their job, they are dependent upon the support from a class of immune system molecules, which have never before been associated with dendritic cells: antibodies.
Willow trees cultivated for green energy can yield up to five times more biofuel if they grow diagonally, compared with those that are allowed to grow naturally up towards the sky. Researchers have identified a genetic trait that causes this effect and is activated in some trees when they sense they are at an angle, such as where they are blown sideways in windy conditions.
In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving ‘double helix’ DNA structure – the chemical code for all life. Now, in the year of that scientific landmark’s 60th Anniversary, Cambridge researchers have published a paper proving that four-stranded ‘quadruple helix’ DNA structures – known as G-quadruplexes – also exist within the human genome.
The Chinese government will give a boost to the biotechnology industry in order to tackle problems related to population growth, food safety, energy conservation and environmental protection, the State Council said. The government aims to double the share of GDP that the sector's value-added output accounts for by 2015 from the 2010 level.
BD (Becton, Dickinson and Company) and the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) through the U.S. Department of Health and Human Services’ Centers for Disease Control and Prevention (CDC) set in motion a joint, multi-year initiative to improve blood collection practices in African clinics and hospitals.