Researchers have decoded the genome of the hookworm, Necator americanus, finding clues to how it infects and survives in humans and to aid in development of new therapies to combat hookworm disease.
The habit of Googling for an online diagnosis before visiting a GP can provide early warning of an infectious disease epidemic. A new study claims internet-based surveillance has been found to detect infectious diseases such Dengue Fever and Influenza up to two weeks earlier than traditional surveillance methods.
McGill researchers, led by Dr. Maya Saleh of the Department of Medicine, have identified an enzyme, cIAP2 that helps the lungs protect themselves from the flu by giving them the ability to resist tissue damage. The results of the now suggest that one effective way of countering influenza infections may instead be offered by enhancing the body’s resistance to the virus.
Duke scientists have taken aim at what may be an Achilles' heel of the HIV virus. Combining expertise in biochemistry, immunology and advanced computation, researchers at Duke University have determined the structure of a key part of the HIV envelope protein, the gp41 membrane proximal external region (MPER), which previously eluded detailed structural description.
Although antiviral therapy against HIV suppresses viral replication and allows infected individuals to live relatively healthy lives for many years, the virus persists in the body, and replication resumes if treatment is interrupted. Now investigators may have found the location where the virus hides – in a small group of recently identified T cells with stem cell-like properties.
An international team of researchers has sequenced the genome of the elephant shark and found new insights into the shark's bone formation and immunity.
Engineers hope a new type of vaccine they have shown to work in mice will one day make it cheaper and easy to manufacture on-demand vaccines for humans. Immunizations could be administered within minutes where and when a disease is breaking out.
Researchers have zoomed in on what is going on at the molecular level when the body recognizes and defends against an attack of pathogens, and the findings, they say, could influence how drugs are developed to treat autoimmune diseases.
Having shingles, a viral infection that causes a painful rash, may increase the risk of having a stroke years later, according to new research.
A new technique for studying the structure of the RSV virion and the activity of RSV in living cells could help researchers unlock the secrets of the virus, including how it enters cells.
Although a population of bacteria may be genetically identical, individual bacteria within that population can act in radically different ways. Researchers showed that when a bacterial cell divides into two daughter cells there can be an uneven distribution of cellular organelles. The resulting cells can behave differently from each other, depending on which parts they received in the split.
The mechanism by which some bacteria are able to survive antibacterial treatment has been revealed for the first time by Hebrew University of Jerusalem researchers. Their work could pave the way for new ways to control such bacteria. Learn more...
A safe and effective malaria vaccine is high on the wish list of most people concerned with global health. Results published this week in PLOS Pathogens suggest how a leading vaccine candidate could be vastly improved.
University at Buffalo research published today in Infection and Immunity shows that Streptococcus pneumoniae and Streptococcus pyogenes do persist on surfaces for far longer than has been appreciated. The findings suggest that additional precautions may be necessary to prevent infections, especially in settings such as schools, daycare centers and hospitals.
Published in the Journal Proceedings of the National Academy of Sciences, senior author, Associate Professor Katherine Kedzierska from the Department of Microbiology and Immunology said that being able to predict which patients will be more susceptible to the emerging influenza strain, will allow clinicians to better manage an early intervention strategy.
A team of researchers from Canada has developed a class of compounds which may help eradicate a neglected tropical disease that is currently hard to kill in its chronic form. The research was published ahead of print in Antimicrobial Agents and Chemotherapy.
Virulent, drug-resistant forms of E. coli that have recently spread around the world emerged from a single strain of the bacteria– not many different strains, as has been widely supposed.
Researchers report promising steps toward the creation of a universal flu vaccine, one that could be produced more quickly and offer broader protection than the virus-specific inoculants available today.
State health researchers have discovered the first new strain of botulism in four decades, but decided to withhold publishing the genetic code because of bioterrorism concerns.
Can an experimental drug developed to treat epilepsy block the AIDS virus? A preliminary lab study suggests it's possible, and researchers are eager to try it in people.
A mosquito-borne virus that kills about half of the people it infects uses a never-before-documented mechanism to “hijack” one of the cellular regulatory systems of its hosts to suppress immunity, according to scientists.
Chinese authorities said Wednesday that a 73-year-old Chinese woman died after being infected with a bird flu strain that had sickened a human for the first time, a development that the World Health Organization called "worrisome."
Researchers have discovered a tube-shaped structure that forms temporarily in a certain type of virus to deliver its DNA during the infection process and then dissolves after its job is completed.
A protein in Salmonella inactivates mast cells- critical players in the body’s fight against bacteria and other pathogens- rendering them unable to protect against bacterial spread in the body, according to researchers.