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Human 3D Skin Models
April 10, 2013 1:36 pm | by Scott Hickman, Marketing Manager, Toxicology, BioReliance Corporation | Articles | Comments
The development of the 3D reconstructed human skin micronucleus (RSMN) assay is the first to overcome the limitations of traditional cell culture methods. It can provide a more biologically relevant result than standard 2D in vitro genotoxicity assays, since it provides a functional stratum corneum, which accounts for permeability and appears to have a normal dermal metabolic capability.
Decoding Cancer Metastasis
May 6, 2013 12:25 pm | by Christina Smith | Articles | Comments
Combining two biological approaches, a research team from University of Michigan broke down the...
The Driving Force of Biomimicry
April 22, 2013 11:38 am | by Cynthia Fox | Articles | Comments
It already has its own peer-reviewed journal, its own economic index and its own institute. As...
Platelet Rich Plasma Significantly Improves Clinical Outcomes in Patients with Tennis Elbow
March 21, 2013 11:58 am | News | Comments
Platelet rich plasma (PRP) therapy has been used to manage pain associated with torn tendons,...
Addiction-blocking Drug Under Development
May 22, 2013 12:50 pm | News | CommentsResearchers have unraveled the molecular foundations of cocaine’s effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice. The compound, already proven safe for humans, is undergoing further animal testing in preparation for possible clinical trials in cocaine addicts.
Radioactive Nanoparticles Target Cancer Cells
May 22, 2013 11:15 am | News | CommentsCancers of all types become most deadly when they metastasize and spread tumors throughout the body. Once cancer has reached this stage, it becomes very difficult for doctors to locate and treat the numerous tumors that can develop. Now, researchers have found a way to create radioactive nanoparticles that target lymphoma tumor cells wherever they may be in the body.
Researchers Closer to Alzheimer's Prevention, Treatment
May 22, 2013 11:10 am | News | CommentsImagine a pharmaceutical prevention, treatment or even cure for Alzheimer’s disease. It is almost impossible to overstate how monumental a development that would be and how it would answer the prayers of millions. Though science isn’t there yet, a new study offers a tantalizing glimpse of potential solutions.
One-step Genetic Engineering Technology Developed
May 22, 2013 10:06 am | News | CommentsA new, streamlined approach to genetic engineering drastically reduces the time and effort needed to insert new genes into bacteria, the workhorses of biotechnology, scientists are reporting. The method paves the way for more rapid development of designer microbes for drug development, environmental cleanup and other activities.
RNA 'Transcriptome' Sequenced in Immune Cells
May 21, 2013 2:22 pm | by Broad Institute of MIT and Harvard | News | CommentsWhen studying any kind of population — people or cells — averaging is a useful, if flawed, form of measurement. According to the US Census Bureau, the average American household size in 2010 was 2.59. Of course, there are no homes with exactly 2.59 people.
Vitamin C Kills Drug-resistant TB
May 21, 2013 12:00 pm | by Einstein | News | CommentsResearchers have determined that vitamin C kills drug-resistant tuberculosis (TB) bacteria in laboratory culture. The finding suggests that vitamin C added to existing TB drugs could shorten TB therapy, and it highlights a new area for drug design.
Salamanders Hold Solution to 'Perfect' Regeneration
May 21, 2013 11:45 am | News | CommentsSalamanders’ immune systems are key to their remarkable ability to regrow limbs, and could also underpin their ability to regenerate spinal cords, brain tissue and even parts of their hearts, scientists have found. New research found that when immune cells known as macrophages were systemically removed, salamanders lost their ability to regenerate a limb and instead formed scar tissue.
New Immune System Discovered
May 21, 2013 11:22 am | News | CommentsMucus may be slimy and gross, but a research team has discovered that it is also home to a powerful immune system that could change the way doctors treat a number of diseases. In this previously undocumented immune system, researchers uncovered bacteria-infecting viruses known as bacteriophage, which shield the body from invading infection.
A New Way to Open Clogged Arteries
May 21, 2013 11:03 am | News | CommentsOver the past few decades, scientists have developed many devices that can reopen clogged arteries, including angioplasty balloons and metallic stents. While generally effective, each of these treatments has drawbacks, including the risk of side effects.
Epigenetics Can Predict Postpartum Depression
May 21, 2013 10:04 am | News | CommentsResearchers say they have discovered specific chemical alterations in two genes that, when present during pregnancy, reliably predict whether a woman will develop postpartum depression. The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester.
'Lifespan Machine' Monitors Worm Aging
May 20, 2013 12:00 pm | by Harvard Medical School | News | CommentsThe worm’s tail wriggles, a micrometer-scale twitch. A scanner captures the new posture. Software recognizes the motion. Life goes on in the Lifespan Machine, a new system devised in the lab of Walter Fontana that, essentially, counts dead worms.
Multitasking Neurons Enhance Brain Flexibility
May 20, 2013 11:40 am | News | CommentsOver the past few decades, neuroscientists have made much progress in mapping the brain by deciphering the functions of individual neurons that perform very specific tasks, such as recognizing the location or color of an object. However, there are many neurons, especially in brain regions that perform sophisticated functions such as thinking and planning, that don’t fit into this pattern.
New MATH Method for Head, Neck Cancer
May 20, 2013 11:05 am | News | CommentsA new method of measuring the variety of genetic mutations found in cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer. The research describes how a new way of measuring tumor heterogeneity was a better predictor of survival than are most traditional risk factors in a small group of patients with squamous cell carcinoma of the head and neck.
Biochemical Transformations Were Possible on Early Earth
May 20, 2013 10:50 am | News | CommentsThe study shows that RNA is capable of catalyzing electron transfer under conditions similar to those of the early Earth. Because electron transfer, the moving of an electron from one chemical species to another, is involved in many biological processes, the study’s findings suggest that complex biochemical transformations may have been possible when life began.
Osteoarthritis Progression Halted
May 20, 2013 10:30 am | News | CommentsScientists have turned their view of osteoarthritis (OA) inside out. Literally. Instead of seeing the painful degenerative disease as a problem primarily of the cartilage that cushions joints, they now have evidence that the bone underneath the cartilage is also a key player and exacerbates the damage.
UK Measles Surge Years After Vaccine Scare
May 20, 2013 6:00 am | by MARIA CHENG - AP Medical Writer - Associated Press | News | CommentsMore than a decade ago, British parents refused to give measles shots to at least a million children because of a vaccine scare that raised the specter of autism. Now, health officials are scrambling to catch up and stop a growing epidemic of the contagious disease. This year, the U.K. has had more than 1,200 cases of measles, after a record number of nearly 2,000 cases last year.
Researchers Aim to Map the 'Food Genome'
May 19, 2013 1:42 pm | by MARY CLARE JALONICK - Associated Press - Associated Press | News | CommentsDo your kids love chocolate milk? It may have more calories on average than you thought. Same goes for soda. Until now, the only way to find out what people in the United States eat and how many calories they consume has been government data, which can lag behind the rapidly expanding and changing food marketplace.
Obesity Linked to 'Vicious Cycle' in Brain
May 17, 2013 11:58 am | News | CommentsWith obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A new study reports the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress appetite and to increase calorie burning.
Auto Emissions Transform Cholesterol
May 17, 2013 11:44 am | News | CommentsAcademic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein (HDL) cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.
Turning Up the Heat on Biofuels
May 17, 2013 11:26 am | News | CommentsThe production of biofuels from lignocellulosic biomass would benefit on several levels if carried out at temperatures between 65 and 70 degrees Celsius. Researchers with the Energy Biosciences Institute (EBI) have employed a promising technique for improving the ability of enzymes that break cellulose down into fermentable sugars to operate in this temperature range.
Method Allows Closer Look at Developing Embryos
May 17, 2013 11:12 am | News | CommentsAn international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before. This result showcases a new method to advance biological research and the search for new treatments for genetic diseases.
Study Suggest New Roles for ECMO
May 17, 2013 10:48 am | News | CommentsExtracorporeal membrane oxygenation (ECMO), a procedure traditionally used during cardiac surgeries and in the ICU that functions as an artificial replacement for a patient's heart and lungs, has also been used to resuscitate cardiac arrest victims in Japan, Taiwan and South Korea.
Stem Cells Generate Immune System in Mice
May 17, 2013 10:36 am | News | CommentsRaising hopes for cell-based therapies, researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. In mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.
WHO says single yellow fever shot is enough
May 17, 2013 3:55 am | by The Associated Press | News | CommentsThe World Health Organization says a yellow fever booster vaccination given 10 years after the initial shot isn't necessary. The U.N.'s global health agency said Friday that its expert group on immunization believes a single dose of vaccination is sufficient to confer lifelong immunity against the disease.
Nanogel Secretes Insulin on Demand
May 16, 2013 11:49 am | News | CommentsInjectable nanoparticles developed at MIT may someday eliminate the need for patients with Type 1 diabetes to constantly monitor their blood-sugar levels and inject themselves with insulin. The nanoparticles were designed to sense glucose levels in the body and respond by secreting the appropriate amount of insulin, thereby replacing the function of pancreatic islet cells, which are destroyed in patients with Type 1 diabetes.
