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Life Science Pulse

Global Strategy Aims to Eradicate Polio by 2018

April 2, 2013 5:44 pm | by LAURAN NEERGAARD - AP Medical Writer - Associated Press | News | Comments

A new global plan aims to end most cases of polio by late next year, and essentially eradicate the paralyzing disease by 2018— if authorities can raise the $5.5 billion needed to do the work, health officials said.

Common Virus Model Used to ‘Fortify’ Adult Stem Cells

April 2, 2013 11:05 am | News | Comments

Using the same strategy that a common virus employs to evade the human immune system, researchers have modified adult stem cells to increase their survival– with the goal of giving the cells time to exert their natural healing abilities.

Crucial DNA Replication Step Revealed

April 2, 2013 10:57 am | News | Comments

For the first time, an elusive step in the process of human DNA replication has been demystified by scientists.

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3D Scaffolds Help Mimic Tumor Growth, Drug Response

April 2, 2013 10:37 am | News | Comments

Researchers reported that three-dimensional scaffolds used to culture Ewing’s sarcoma cells were effective at mimicking the environment in which such tumors develop.

New Brain Cancer Treatment Uses Bone Marrow Cells

April 2, 2013 10:22 am | News | Comments

In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers have discovered a novel approach for treatment of tumors.

Research Deciphers HIV Attack Plan

April 2, 2013 9:58 am | News | Comments

A new study defines previously unknown properties of transmitted HIV-1, the virus that causes AIDS.

Blood Clotting, Immune Response Linked

April 2, 2013 9:40 am | News | Comments

Researchers have found an unexpected link between a protein that triggers the formation of blood clots and other proteins that are essential for the body’s immune system.

How Cells Distinguish Friend from Foe

April 1, 2013 10:57 am | News | Comments

Researchers have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes.

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Study Reveals Mutant Histone Mechanism in Brain Cancer

April 1, 2013 10:36 am | News | Comments

Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research may bring scientists closer to designing cancer therapeutics that can target tumors with pinpoint accuracy.

Following the Body’s Own Prescription

April 1, 2013 10:22 am | by Cynthia Fox | Articles | Comments

An intuitive approach, which co-opts the body’s own molecular machinery, has led to massive expansions of umbilical cord blood cells. It and other new approaches “will revolutionize all transplantation,” says University of Minnesota Blood and Marrow Transplantation Director John Wagner.

Code-reading Machinery Collisions Speed Gene Evolution

April 1, 2013 10:18 am | News | Comments

Bacteria appear to speed up their evolution by positioning specific genes along the route of expected traffic jams in DNA encoding. Certain genes are in prime collision paths for the moving molecular machineries that read the DNA code, scientists explain.

ALS Discovery Holds Promise for New Treatments

April 1, 2013 10:03 am | News | Comments

Scientists said they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a fatal degenerative disease.

Questions in China on Deadly, Lesser-Known Bird Flu

April 1, 2013 7:34 am | by GILLIAN WONG - Associated Press - Associated Press | News | Comments

Health officials say they still don't understand how a lesser-known bird flu virus was able to kill two men and seriously sicken a woman in China, but that it's unlikely that it can spread easily among humans. Two men in Shanghai became the first known human fatalities from the H7N9 bird flu after contracting it in February.

CDC: E. Coli Outbreak Linked to Frozen Foods

March 29, 2013 6:09 pm | by MIKE STOBBE - AP Medical Writer - Associated Press | News | Comments

Health officials say at least 24 people have become sick from an outbreak of E. coli infections linked to frozen snack foods marketed to children. No one has died, but eight people, mostly kids or teens, were hospitalized.

Technique Detects ‘Sugar-coated’ Proteins in Blood

March 29, 2013 11:23 am | News | Comments

Scientists have developed a new technique that could be used in blood tests to detect a range of age-related conditions such as diabetes, dementia and Alzheimer’s.

Cells, Cell Fragments Move in Opposite Directions

March 29, 2013 11:07 am | News | Comments

Like tiny, crawling compass needles, whole living cells and cell fragments orient and move in response to electric fields— but in opposite directions, scientists have found.

Stem Cell Fate Depends on ‘Grip’

March 29, 2013 10:52 am | News | Comments

A team of researchers has generated new insight on how a stem cell’s environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can “grip” the material they are growing in.

New Vaccine Approach Targets HIV, Other Fast-mutating Viruses

March 29, 2013 10:41 am | News | Comments

A team of scientists has unveiled a new technique for vaccine design that could be particularly useful against HIV and other fast-changing viruses.

Cell Reprogramming During Liver Regeneration

March 29, 2013 10:28 am | News | Comments

Researchers have been able to reprogram cells experimentally, but few have shown that cells can change their identities under normal physiological conditions in the body, particularly in mammals.

Riding the Exosome Shuttle from Neuron to Muscle

March 28, 2013 1:43 pm | News | Comments

Important new research demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting discovery that means these tiny vehicles could one day be loaded with therapeutic agents, such as RNA interference (RNAi), and directly target disease-carrying cells.

Schwann Cells Play Role in Neuropathic Pain

March 28, 2013 10:49 am | News | Comments

An international team of scientists says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery of peripheral nerves after injury.

Rare Brain Disorders Linked to Splicing Slip-ups

March 28, 2013 10:38 am | by Harvard Medical School | News | Comments

Researchers have found that missteps in a basic cellular process, RNA splicing, is the culprit behind a class of rare neurological disorders manifested by intellectual disability and stunted development.

Rats’ Brains are More Like Ours Than Previously Thought

March 28, 2013 10:05 am | News | Comments

Neuroscientists face a multitude of challenges in their efforts to better understand the human brain. If not for model organisms such as the rat, they might never know what really goes on inside our heads.

E. Coli Study Leads to New Therapeutic Target

March 28, 2013 9:57 am | News | Comments

A new study provides novel insight into how an emerging strain of the diarrhea-causing bacteria E. coli interacts with its host.

Common Foods Cause DNA Damage

March 28, 2013 9:35 am | News | Comments

In a laboratory study pairing food chemistry and cancer biology, scientists tested the potentially harmful effect of foods and flavorings on the DNA of cells. They found that liquid smoke flavoring, black and green teas and coffee activated the highest levels of a well-known, cancer-linked gene called p53.

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