The reason so many spinal cord injuries are permanently disabling is that the human body lacks the capacity to regenerate nerve fibers. Now, new research describes how a protein named P45 may yield insight into a possible molecular mechanism to promote rerouting for spinal cord healing and functional recovery.
As part of the innate immune system, natural killer cells (NK cells) play an important role in immune responses. While researchers typically assumed that the body needs as many active NK cells as possible, scientists have now shown that the principle of “the more the better” does not apply to this type of immune cell.
Silk has walked straight off the runway and into the lab. According to a new study, silk implants placed in the brain of laboratory animals and designed to release a specific chemical, adenosine, may help stop the progression of epilepsy.
Scientists believe the proteins that are targeted by cosmetic surgery treatment Botox could hold the secret to treating and even curing Type 2 diabetes. A team of researchers is using new molecular microscopic techniques on SNARE proteins to solve the mystery of how insulin release is regulated and how this changes during Type 2 diabetes.
In a step toward understanding how faulty memories arise, neuroscientists have shown that they can plant false memories in the brains of mice. They also found that many of the neurological traces of these memories are identical in nature to those of authentic memories.
The taller a postmenopausal woman is, the greater her risk for developing cancer, according to a new study. Height was linked to cancers of the breast, colon, endometrium, kidney, ovary, rectum, and thyroid, as well as to multiple myeloma and melanoma.
As the U.S. Food and Drug Administration (FDA) continues to finalize regulations to establish a pathway for approving biopharmaceutical or biosimilar drugs, leading branded drug manufacturers are looking ahead and lobbying state legislatures to enact laws that would limit the substitution of biogenerics for brand-name drugs.
Using gold nanoparticles, researchers have devised a new way to turn blood clotting on and off. The particles, which are controlled by infrared laser light, could help doctors control blood clotting in patients undergoing surgery, or promote wound healing.
Key molecular pathways that ultimately lead to late-onset Alzheimer’s disease, the most common form of the disorder, have been identified by researchers. The study, which used a combination of systems biology and cell biology tools, presents a new approach to Alzheimer’s disease research and highlights several new potential drug targets.
Regular marijuana use in adolescence, but not adulthood, may permanently impair brain function and cognition, and may increase the risk of developing serious psychiatric disorders such as schizophrenia, according to a recent preclinical study. Researchers hope that the study will help to shed light on the potential long-term effects of marijuana use.
The discovery of a gene's function in E. coli and other bacteria might lead to a probiotic to prevent the most common type of kidney stone, according to a new study. The team made the discovery during a study of genes in Acetobacter aceti, a harmless bacterium that is typically used to convert wine to vinegar.
Federal health authorities say more than 275 people in seven states have now been sickened with an unidentified stomach bug. The Food and Drug Administration is investigating the cyclospora infections, which are often found in tropical or subtropical countries and have been linked to imported fresh produce in the past.
Newly trialed native algae species provide real hope for the development of commercially viable fuels from algae, scientists have found. The researchers have identified fast-growing and hardy microscopic algae that could prove the key to cheaper and more efficient alternative fuel production.
Scientists have revealed new images which provide the clearest picture yet of how white blood immune cells attack viral infections and tumors. They show how the cells change the organization of their surface molecules when activated by a type of protein found on viral-infected or tumor cells.
Borrowing a tool from molecular biology, researchers have detected a tumor-associated genetic mutation in the cerebrospinal fluid (CSF) of a small number of patients with brain tumors. The investigators used digital versions of the gene-amplification technology polymerase chain reaction (PCR) to analyze bits of RNA carried in membrane-covered sacs.
Researchers have unraveled the secret to byssus threads, the tiny natural bungee cords that mussels use to dangle loosely from rocks, piers or ships. Byssus threads, they found, are composed of a well-designed combination of soft, stretchy material on one end and much stiffer material on the other.
A new biosensor, applied to the human skin like a temporary tattoo, can alert marathoners, competitive bikers and other “extreme” athletes that they’re about to “bonk,” or “hit the wall,” scientists are reporting. The sensor could also help soldiers and others who engage in intense exercise, and their trainers, monitor stamina and fitness.
An Air Force recruit whose organs were donated to four patients including a kidney recipient who died of rabies had at least two untreated raccoon bites several months before he became sick, and tests confirm his rabies-infected kidney caused the recipient's disease. Lab testing found evidence of rabies in the donor's brain tissue and also detected encephalitis, a brain inflammation that can be caused by rabies.
In older men, a natural antioxidant compound found in red grapes and other plants– called resveratrol– blocks many of the cardiovascular benefits of exercise, according to results from a recent research project. The research unusually suggests that eating a diet rich in antioxidants may actually counteract many of the health benefits of exercise.
In a new paper, a team of researchers show that the pulmonary vasculature, the blood vessels that connect the heart to the lung, develops even in the absence of the lung. Mice in which lung development is inhibited still have pulmonary blood vessels, which revealed that cardiac progenitors, or stem cells, are essential for cardiopulmonary co-development.
One of regenerative medicine's greatest goals is to develop new treatments for stroke. Stem cell research for the disease has typically focused on developing therapeutic neurons to repair damaged brain tissue. Now, a new study found that astrocytes can protect brain tissue and reduce disability due to stroke and other ischemic brain disorders.
A research team has identified circuitry in the brain that drives compulsive drinking in rats, and likely plays a similar role in humans. They found they could reduce compulsive drinking in rats by inhibiting key neural pathways that run between the prefrontal cortex and the nucleus accumbens.
A type of fungus coating much of the stored corn, wheat, rice and nuts in developing countries may be quietly worsening the AIDS epidemic, according to a new study. Kept in sacks piled in barns and warehouses, food stores in countries near the equator are contaminated by Aspergillus flavus and A. parasiticus, fungi that produce a toxic substance called aflatoxin.
Another reason to eat breakfast: Skipping it may increase your chances of a heart attack. A study of older men found those who regularly skipped breakfast had a 27 percent higher risk of a heart attack than those who ate a morning meal.
For the first time, scientists are working on developing a ‘nano-coating’ that would protect a vaccine from its environment both in transit and for storage. Using the latest chemistry advances, researchers hope to show how nano-silica can be grown around individual vaccine molecules, enabling a vaccine to be taken anywhere in the world without refrigeration.