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Study Shows Where Alzheimer's Starts, How It Spreads

December 23, 2013 11:40 am | News | Comments

Using high-resolution functional MRI (fMRI) imaging in patients with Alzheimer's disease and in mouse models of the disease, Columbia University Medical Center (CUMC) researchers have clarified three fundamental issues about Alzheimer's: where it starts, why it starts there and how it spreads. In addition to advancing understanding of Alzheimer's, the findings could improve early detection of the disease. Learn more...

Innovative Screening Strategy Uncovers New Drugs, Biology

December 23, 2013 11:15 am | News | Comments

Scientists at The Scripps Research Institute (TSRI) have demonstrated a drug-discovery strategy with a double payoff—it enables the rapid selection of chemical compounds that have a desired effect on cells and also highlights how the compounds work. To illustrate the power of the innovative technique, the TSRI researchers used it to identify a compound that shows promise for treating obesity-linked diabetes. Learn more...

Some Plants May Not Adapt to Climate Change

December 23, 2013 10:56 am | News | Comments

Using the largest dated evolutionary tree of flowering plants ever assembled, a new study suggests how plants developed traits to withstand low temperatures, with implications that human-induced climate change may pose a bigger threat than initially thought to plants and global agriculture.

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New, Reversible Cause of Aging Discovered

December 20, 2013 12:29 pm | News | Comments

Researchers have discovered a cause of aging in mammals that may be reversible. The essence of this finding is a series of molecular events that enable communication inside cells between the nucleus and mitochondria.          

Neanderthal Genome Exposes Interbreeding

December 20, 2013 12:17 pm | News | Comments

An international research team has completed the first high-quality genome sequence of a Neanderthal, deepening knowledge about the genetic connections and population histories of ancient and modern humans.             

Study IDs, Breaks Down 'Wall' Around Tumors

December 20, 2013 12:12 pm | News | Comments

Researchers have identified how the ‘wall’ around cancer tumors functions and how to break it down, enabling the body’s own defenses to reach and kill the cancer cells within.                     

Drug-resistant E. Coli Emerged from Single Strain of Bacteria

December 20, 2013 11:57 am | News | Comments

Virulent, drug-resistant forms of E. coli that have recently spread around the world emerged from a single strain of the bacteria– not many different strains, as has been widely supposed.                     

One Step Closer to a 'Universal' Flu Vaccine

December 20, 2013 11:49 am | News | Comments

Researchers report promising steps toward the creation of a universal flu vaccine, one that could be produced more quickly and offer broader protection than the virus-specific inoculants available today.              

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Stress Gene Ups Death, Heart Attack Risk

December 20, 2013 11:29 am | News | Comments

A genetic trait known to make some people especially sensitive to stress also appears to be responsible for a 38 percent increased risk of heart attack or death in patients with heart disease, scientists report.           

Genetic Code of New Botulism Strain Withheld

December 19, 2013 4:34 pm | by The Associated Press | News | Comments

State health researchers have discovered the first new strain of botulism in four decades, but decided to withhold publishing the genetic code because of bioterrorism concerns.                     

Drug Blocks HIV in Lab, Human Tests Planned

December 19, 2013 2:51 pm | by MALCOLM RITTER - AP Science Writer - Associated Press | News | Comments

Can an experimental drug developed to treat epilepsy block the AIDS virus? A preliminary lab study suggests it's possible, and researchers are eager to try it in people.                        

Possible Ban on Trans Fat Forces Health Questions About Substitutes

December 19, 2013 11:39 am | News | Comments

Health advocates cheered last month’s FDA proposal to ban partially hydrogenated oils— which contain trans fats that increase the risk of heart disease— but some wonder whether the substitutes for these fats will be any healthier.      

Role of Sugar Uptake in Breast Cancer Revealed

December 19, 2013 11:33 am | News | Comments

Metabolism was lost in the shadows of cancer research for decades but has recently been reclaiming some of the spotlight. Now, research has shown that aerobic glycolysis is not the consequence of the cancerous activity of malignant cells but is itself a cancerous event.

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Immune Mechanism May Lead to Mosquito-borne Virus Treatments

December 19, 2013 11:24 am | News | Comments

A mosquito-borne virus that kills about half of the people it infects uses a never-before-documented mechanism to “hijack” one of the cellular regulatory systems of its hosts to suppress immunity, according to scientists.         

Lessening X-ray Damage is Healthy for Protein Discovery

December 19, 2013 11:18 am | News | Comments

New recommendations for using X-rays promise to speed investigations aimed at understanding the structure and function of biologically important proteins– information critical to the development of new drugs.            

Brain Connections Explain Why Girls Mature Faster

December 19, 2013 10:35 am | News | Comments

Scientists have discovered that as the brain reorganizes connections throughout our life, the process begins earlier in girls which may explain why they mature faster during the teenage years.                 

No Association Between Iron, Atherosclerosis, Study Says

December 18, 2013 12:23 pm | News | Comments

A research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease.               

Lung Cancer Mutations Also Drive Colorectal Cancer

December 18, 2013 12:09 pm | News | Comments

A new study shows that ALK and ROS1 gene rearrangements known to drive subsets of lung cancer are also present in some colorectal cancers.                                

Gene Linked to Asperger Syndrome, Empathy

December 18, 2013 12:04 pm | News | Comments

Scientists have confirmed that variations in a particular gene play a key role in the autism spectrum condition known as Asperger Syndrome, and that variations in the same gene are also linked to differences in empathy levels.       

Researchers Discover a ‘Teen’ Gene

December 18, 2013 11:49 am | News | Comments

Researchers have isolated a gene, DCC, which is responsible for dopamine connection in the medial prefrontal cortex during adolescence and established that dysfunction of this gene during adolescence leads to behavioral consequences in adulthood.

An Apple a Day Does Keep the Doctor Away

December 18, 2013 11:28 am | News | Comments

Prescribing an apple a day to all adults aged 50 and over would prevent or delay around 8,500 vascular deaths such as heart attacks and strokes every year in the UK, according to a new study.                 

Higher Blood Pressure Threshold OK in Older Adults

December 18, 2013 11:13 am | by LINDSEY TANNER - AP Medical Writer – Associated Press | News | Comments

Many older adults with high blood pressure can be treated less aggressively, which could mean taking fewer pills to get it under control, according to new treatment guidelines from an expert panel.                

Bird Flu Strain Kills Human for the First Time

December 18, 2013 1:01 am | by GILLIAN WONG - Associated Press - Associated Press | News | Comments

Chinese authorities said Wednesday that a 73-year-old Chinese woman died after being infected with a bird flu strain that had sickened a human for the first time, a development that the World Health Organization called "worrisome."     

Virus Grows Tube, Then Sheds It, to Insert DNA During Infection

December 17, 2013 11:22 am | News | Comments

Researchers have discovered a tube-shaped structure that forms temporarily in a certain type of virus to deliver its DNA during the infection process and then dissolves after its job is completed.                

‘Chemobrain’ Linked to Disrupted Brain Networks

December 17, 2013 11:15 am | News | Comments

For some cancer patients, the mental fogginess that develops with chemotherapy lingers long after treatment ends. Now, research in breast cancer patients may offer an explanation.                     

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