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The Lead

Cloning Making a Comeback?

April 18, 2014 1:46 pm | by Cynthia Fox | Articles | Comments

Cloning has finally generated immunologically compatible embryonic stem cells for older humans: two men aged 35 and 75. It may also generate significantly fewer tumor-causing mutations than the popular induced pluripotent stem cell (iPSC) method of making ES cells.

Researchers Develop New Model of Cellular Movement

April 18, 2014 12:27 pm | News | Comments

Cell movement plays an important role in a host of biological functions from embryonic...

Chronic Inflammation May Be Linked to Aggressive Prostate Cancer

April 18, 2014 12:11 pm | News | Comments

The presence of chronic inflammation in benign prostate tissue was associated with high-grade,...

Lost Stem Cells Naturally Replaced by Non-stem Cells

April 18, 2014 11:58 am | News | Comments

Researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit...

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Protein Essential for Fertilization Discovered

April 17, 2014 1:06 pm | Videos | Comments

Researchers have discovered interacting proteins on the surface of the sperm and the egg essential to begin mammalian life. These proteins offer new paths towards improved fertility treatments and the development of new contraceptives.     

Scientists Explain How Memories Stick Together

April 17, 2014 12:46 pm | News | Comments

Scientists have created a new model of memory that explains how neurons retain select memories a few hours after an event. This new framework provides a more complete picture of how memory works, which can inform research into disorders liked Parkinson's and Alzheimer's.

Groundbreaking MRI Scan Shows Brown Fat in Tissues

April 17, 2014 12:22 pm | News | Comments

Researchers used an MRI-based method to identify and confirm the presence of brown adipose tissue in a living adult, which could prove to be an essential step towards a new wave of therapies to aid the fight against diabetes and obesity.   

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Ebola Virus in Africa Outbreak is New Strain

April 16, 2014 5:21 pm | by Marilynn Marchione - AP Chief Medical Writer | News | Comments

The Ebola virus that has killed scores of people in Guinea this year is a new strain - evidence that the disease did not spread there from outbreaks in some other African nations, scientists report.               

Teenage Concussions Linked to Higher Rates of Suicide Attempts

April 16, 2014 2:04 pm | News | Comments

Teenagers who have suffered a traumatic brain injury such as a concussion are at “significantly greater odds” of attempting suicide, being bullied and engaging in a variety of high risk behaviors, a new study has found.          

Diabetes Cases Nearly Doubled Over Past Two Decades

April 16, 2014 1:52 pm | News | Comments

Cases of diabetes and pre-diabetes in the United States have nearly doubled since 1988, suggests new research, with obesity apparently to blame for the surge.                           

Scientists Discover Brain’s Anti-distraction System

April 16, 2014 1:38 pm | News | Comments

Psychologists have presented the first study to reveal that our brains rely on an active suppression mechanism to avoid being distracted by salient irrelevant information when we want to focus on a particular item or task.         

DNA Looping Damage Tied to HPV Cancer

April 16, 2014 1:26 pm | News | Comments

It’s long been known that certain strains of human papillomavirus (HPV) cause cancer. Now, researchers have determined a new way that HPV might spark cancer development– by disrupting the human DNA sequence with repeating loops when the virus is inserted into host-cell DNA as it replicates.

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Breaking News: Marijuana Use Linked to Brain Abnormalities

April 16, 2014 8:30 am | News | Comments

Young adults who used marijuana only recreationally showed significant abnormalities in two brain regions that are important in emotion and motivation. This is the first study to show casual use of marijuana is related to major brain changes.  

Young Dads at High Risk of Depression, Too

April 15, 2014 12:07 pm | News | Comments

Depression can hit young fathers hard- with symptoms increasing dramatically during some of the most important years of their children’s lives, a new study has found.                        

First Volunteers to Receive Blood Cultured from Stem Cells in 2016

April 15, 2014 12:01 pm | News | Comments

The first human volunteer will receive red blood cells cultured in the laboratory within the next three years, as part of a long-term research program funded by the Wellcome Trust.                    

Drawing a Ring Around Antiviral Immunity

April 15, 2014 11:37 am | News | Comments

If you follow cancer biology, then you’ve probably heard of ubiquitin before. In a recent paper researchers provided a structural rationale for how ubiquitin helps RIG-I do its job— and how that might help keep the immune system from getting out of hand.

Central Ohio Mumps Outbreak Tops 200 Cases

April 14, 2014 8:18 pm | by The Associated Press | News | Comments

A mumps outbreak in central Ohio has grown to more than 200 confirmed cases, public health officials said. A total of 212 cases of the contagious viral illness, with 132 of those linked to Ohio State University, have been reported.    

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Breaking News: Coffee Intake Linked to Liver Cancer Risk

April 9, 2014 11:16 am | News | Comments

The more cups of coffee a person drank, the lower the risk for developing hepatocellular carcinoma (HCC), the most common type of liver cancer, according to new research.                       

Blood Test Could Accurately Detect Solid Cancers

April 7, 2014 2:12 pm | News | Comments

Researchers have devised a way to quickly bring to the clinic the technique of using blood samples to diagnose many types of solid cancers, or to monitor the amount of cancer in a patient’s body and responses to treatment.        

Movies Synchronize Brains of Different People

April 7, 2014 1:58 pm | News | Comments

Researchers have succeeded in developing a method fast enough to observe immediate changes in the function of the brain even when watching a movie. When we watch a movie, our brains react to it immediately in a way similar to other people's brains.

Scientists ID Key Cells in Touch Sensation

April 7, 2014 1:49 pm | Videos | Comments

In a new study, researchers solved an age-old mystery of touch: how cells just beneath the skin surface enable us to feel fine details and textures.                              

Genetic Flaw May Hold Key to Deadly Brain Tumor

April 7, 2014 1:41 pm | News | Comments

Scientists may have discovered a new way to treat a type of childhood brain tumor that has proved incurable up until now, according to a recent study.                             

Scientists Generate 3-D Structure of Malaria Parasite Genome

April 7, 2014 1:21 pm | News | Comments

Researchers have generated a 3-D model of the human malaria parasite genome at three different stages in the parasite’s life cycle— the first time such 3-D architecture has been generated during the progression of the life cycle of a parasite.  

Caffeine Can Target Tau Deposits in Alzheimer's

April 7, 2014 12:33 pm | News | Comments

A research team was able to demonstrate for the first time that caffeine has a positive effect on tau deposits in Alzheimer's disease. Tau deposits, along with beta-amyloid plaques, are among the characteristic features of Alzheimer's disease. 

Messenger of Pain Identified

April 7, 2014 12:10 pm | News | Comments

In their pursuit of understanding how pain works at the molecular level, a research team has found a new function for MicroRNAs, short stretches of genetic material that signal genes to turn on or off.               

Experts Decode Germs' DNA to Fight Food Poisoning

April 6, 2014 8:18 am | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

Chances are you've heard of mapping genes to diagnose rare diseases, predict your risk of cancer and tell your ancestry. But to uncover food poisonings? The nation's disease detectives are beginning a program to try to outsmart outbreaks by routinely decoding the DNA of potentially deadly bacteria and viruses.

Brain Degeneration in Huntington’s Caused by Amino Acid Deficiency

March 27, 2014 12:58 pm | News | Comments

Neuroscientists report they have identified what they believe is the cause of the vast disintegration of a part of the brain called the corpus striatum in rodents and people with Huntington’s disease: loss of the ability to make the amino acid cysteine.

3-D MRI Scans Can Predict Survival After Targeted Chemo for Liver Tumors

March 27, 2014 12:48 pm | News | Comments

In a series of studies researchers have used specialized 3-D MRI scans to precisely measure living and dying tumor tissue to quickly show whether highly toxic chemotherapy is working.                   

Genetics Explain Why Infections Trigger Rheumatoid Arthritis

March 27, 2014 12:40 pm | News | Comments

A team of researchers believe their findings could have important implications for the way that rheumatoid arthritis is diagnosed and treated. They say that more accurate clinical testing is now needed to better identify rheumatoid arthritis and to prevent it being misdiagnosed.

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