Cytomegalovirus, or CMV, is perhaps one of the biggest pathogens you’ve never heard of—big, both proportionately and epidemiologically. If you’re healthy, it’s harmless, but if you have an impaired immune system, the virus can assert itself with a vengeance. Now, researchers have discovered a menu of tactical secrets CMV employs.
The calorie-burning triggered by cold temperatures can be achieved biochemically– without the chill– raising hopes for a weight-loss strategy focused on the immune system rather than the brain, according to a new study.
Metastatic cancer cells, which can migrate from primary tumors to seed new malignancies, have thus far been resistant to the current arsenal of anticancer drugs. Now, researchers have identified a critical weakness that actually exploits one of these cells’ apparent strengths—their ability to move and invade tissues.
A large new analysis of DNA from thousands of patients has uncovered several underlying gene networks with potentially important roles in autism. These networks may offer attractive targets for developing new autism drugs or repurposing existing drugs that act on components of the networks.
Improved diagnosis and management of one of the most common cancers in men- prostate cancer- could result from research, which has discovered that seminal fluid (semen) contains biomarkers for the disease.
You are what you eat, but researchers are beginning to realize that what and when you eat is controlled by a myriad of underlying biological triggers acting in concert.
A new study shows how exposure to air pollution early in life produces harmful changes in the brains of mice, including an enlargement of part of the brain that is seen in humans who have autism and schizophrenia.
The popular “Paleo diet,” oft described as an ancient diet dominated by grasses and modeled after diets from the Paleolithic period, may not quell hunger better than the modern “McDonald’s” diet.
Surgery and radiation for a glioblastoma have only limited effectiveness because the tumor is particularly aggressive, infiltrating brain tissue surrounding the primary tumor. Scientists have developed a technique designed to open the blood-brain barrier at targeted locations just far enough to allow the passage of drug-bearing nanoparticles.
By studying laboratory mice, scientists have succeeded in plotting the labyrinthine paths of some of the largest nerve cells in the mammalian brain: cholinergic neurons, the first cells to degenerate in people with Alzheimer’s disease.
Scientists have discovered that bacteria can reshape their DNA to survive dehydration. The research shows that bacterial DNA can change from the regular double helix to the more compact A-DNA form, when faced with hostile conditions such as dehydration.
While it was known that a specific birch pollen protein causes the immune system to overreact, the exact reason why many people are allergic to birch pollen had not yet been fully clarified. Now, scientists at the Vetmeduni Vienna have discovered what makes the protein an allergen.
Young men who use cannabis may be putting their fertility at risk by inadvertently affecting the size and shape of their sperm, according to recently published research.
Nutritionists regularly suggest breakfast be eaten each morning for health benefits, including weight loss. But new research shows that, when comparing regularly consuming with regularly skipping breakfast, weight loss was not influenced.
A new report offers the strongest evidence yet that a mysterious Middle East virus spreads from camels to people. Researchers studied the illness of a 44-year-old camel owner in Saudi Arabia, who died in November of Middle East respiratory syndrome, or MERS.
Limiting saturated fat could help people whose genetic make-up increases their chance of being obese, according to a new study. The findings could be useful in identifying people who are predisposed to obesity and could ultimately lead to personalized dietary recommendations.
A test that counts the number of locations in tumor specimens where tumor cells may invade blood vessels predicted the risk of distant spread, or metastasis, for the most common type of breast cancer.
Researchers are reporting promising treatment milestones for patients with deadly skin and lung cancers who are being treated with an experimental drug called MK-3475.
One of the biggest challenges for medical researchers studying the effectiveness of stem cell therapies is that transplants or grafts of cells are often rejected by the hosts. Now, researchers have shown that a new line of genetically modified pigs will host transplanted cells without the risk of rejection.
Christofer Toumazou believes he can change the world with his “one chip, one bug – one chip, one drug,” slogan. Nominated for the European Patent Office’s 2014 European Inventor award, he holds a patent for the technology behind a microchip that can analyze DNA within 30 minutes and without a laboratory.
A Purdue University-led research team has figured out how to disable a part of the SARS virus responsible for hiding it from the immune system; a critical step in developing a vaccine against the deadly disease. The findings also have potential applications in the creation of vaccines against other coronaviruses, including MERS.
By analyzing the blood of almost 100 treated and untreated HIV-infected volunteers, a team of scientists has identified previously unknown characteristics of B cells in the context of HIV infection.
Researchers at King’s College London have discovered how a molecular ‘scaffold’ which allows key parts of cells to interact, comes apart in dementia and motor neuron disease (such as ALS), revealing a potential new target for drug discovery.
Researchers have found a new type of neuron in the adult brain that is capable of telling stem cells to make more new neurons. Though the experiments are in their early stages, the finding opens the tantalizing possibility that the brain may be able to repair itself from within.
Children who later develop autism are exposed to elevated levels of steroid hormones (for example testosterone, progesterone and cortisol) in the womb, according to scientists. The finding may help explain why autism is more common in males than females. However, the researchers caution it should not be used to screen for the condition.