Scientists have identified a gene encoding a hormone that could potentially be used as a therapeutic molecule to treat heart diseases. The hormone- which they have chosen to name ELABELA- is only 32 amino-acids long, making it one of the tiniest proteins made by the human body.
A new study shows out that mice with a mutation in the gene for the protease Tmprss2 do not...
In search of better cancer treatments, researchers have designed synthetic molecules that...
Using a powerful gene-hunting technique, researchers report they have identified a gene involved in building the circuitry that relays signals through the brain.
Coffee and beer are polar opposites in the beverage world. Coffee picks you up, and beer winds you down. Now, researchers have discovered that the beverages may also have opposite effects on your genome.
Genetic testing company 23andMe is facing a class action lawsuit alleging that the Silicon Valley startup misled customers about its test kit. The test is promoted as helping predict users' disease risk based on their DNA.
Researchers have identified a new genetic variant, located on chromosome 17, associated with sporadic amyotrophic lateral sclerosis (ALS)– the most common form of motor neuron disease.
Investigators have accomplished an important step toward their goal of creating primitive synthetic cells. The “protocells” they are building consist of a nucleic acid strand encased within a membrane-bound compartment.
Research has suggested that a particular gene in the brain’s reward system contributes to overeating and obesity in adults.
Using a special MRI technique designed for studies of sleeping infants, researchers have found that infants who carry a gene associated with an increased risk for Alzheimer’s disease tend to have differences in brain development compared to infants who do not carry the gene.
Women who are members of families with BRCA2 mutations but who test negative for the family-specific BRCA2 mutations are still at greater risk for developing breast cancer compared with women in the general population, according to a new study.
Scientists have used RNA interference (RNAi) technology to reveal dozens of genes which may represent new therapeutic targets for treating Parkinson’s disease.
Asparagine, found in foods such as meat, eggs, and dairy products, was until now considered non-essential because it is produced naturally by the body. Researchers have now found that the amino acid is essential for normal brain development.
The Food and Drug Administration has ordered Google-backed genetic test maker 23andMe to halt sales of its personalized DNA test kits, saying the company has failed to show that the technology is supported by science.
Recent studies have linked hundreds of gene mutations scattered throughout the brain to increased autism risk. Where do you start? Neuroscientists may finally have an answer.
Using a new method to catch elusive “jumping genes” in the act, researchers have found two human proteins that are used by one type of DNA to replicate itself and move from place to place.
The switches in our epigenome help alter the way our cells act and are impacted by environmental factors including diet, exercise and stress. Research at the Buck Institute reveals that aging also effects the epigenome in human skeletal muscle.
Western blotting is a technique routinely used by researchers to detect and identify certain proteins of interest in a sample. Although a well-established and explored method, a number of shortcomings need to be addressed to enable Western blotting to deliver standardized and quantitative data, supporting researchers who require reproducible, high-quality results to move their research forward.
The U.S. Food and Drug Administration allowed marketing of four diagnostic devices that can be used for high throughput gene sequencing, often referred to as “next generation sequencing” (NGS). These instruments, reagents and test systems allow labs to sequence a patient’s DNA.
Despite large international efforts to catalogue the genes that influence the stature of humans, knowledge on genetic determinants of adult body height is still incomplete. Now, DNA-based prediction of taller-than-average body height is feasible, as reported by researchers.
British biochemist Frederick Sanger, who twice won the Nobel Prize in chemistry and was a pioneer of genome sequencing, has died at the age of 95. His death was confirmed Wednesday by the MRC Laboratory of Molecular Biology - which Sanger helped found.
A new method to take the DNA fingerprint of individual cancer cells is uncovering the true extent of cancer’s genetic diversity, new research reveals. The technique can identify the founding mutations from which a tumor evolved and then uses computer software to draw a map of the cancer’s family tree.
Investigators have used a new sequencing method to identify a group of genes used by the brain's immune cells– called microglia– to sense pathogenic organisms, toxins or damaged cells that require their response.
Washington University School of Medicine in St. Louis now offers genetic testing to help diagnose and treat patients with heart disorders that can lead to sudden death.
Researchers report that the deletion of any single gene in yeast cells puts pressure on the organism’s genome to compensate, leading to a mutation in another gene.
Researchers have taken a step forward in unravelling the causes of a commonly inherited intellectual disability, finding that a genetic mutation leads to a reduction in certain proteins in the brain.
A protein engineered by combining proteins active in HIV and Moloney murine leukemia virus (MLV) replication may lead to safer, more effective retroviral gene therapy.
What does it mean to be human? According to scientists the key lies in the billions of lines of genetic code that comprise the human genome. The problem has been deciphering that code. But now, researchers have discovered how the activation of specific stretches of DNA control the development of uniquely human characteristics.
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