More than a decade after the completion of Human Genome Project, precision medicine has struggled with what it known as the "last mile." Despite major leaps in the field, the technical work needed to integrate genomic information into the day-to-day practice of medicine has lagged far behind.
Scientists have sequenced the mitochondrial genome in glaucoma patients to help further understanding into the genetic basis for the disease. Glaucoma is a major cause of irreversible blindness, affecting more than 60 million people worldwide.
A research team has used whole genome sequencing to identify a new genetic cause of a severe, rare and complex form of epilepsy that becomes evident in early childhood and can lead to early death.
Bacteria in colonies don’t reproduce sexually and are genetically identical, yet they can prepare in advance for changing environmental conditions. Researchers have shown that bacteria carry out this strategy by producing cells with differing amounts of specific proteins that govern their response to chemical signals.
The human populations now predominant in Eurasia and East Asia probably split between 36,200 and 45,000 years ago, according to a study released Thursday.
Ebola and Marburg are 16 to 23 million years old, not thousands of years old as once thought, according to a new study. The research also indicates that while Ebola and Marburg diverged from each other millions of years ago.
Asthma may be more harmful than was previously thought, according to researchers who found that genetic damage is present in circulating, or peripheral, blood.
Geneticists report they have developed a novel tool— dubbed “the telomerator”— that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed in the laboratory based on an organism’s genetic, chemical base-pair structure.
Genetically engineering tumors in mice, a technique that has dominated cancer research for decades, may not replicate important features of cancers caused by exposure to environmental carcinogens, according to a new study.
Through a new, semi-secretive extension of the company, Google is working on a slew of ambitious projects that could drastically revolutionize healthcare as we know it.
As potential next-generation therapeutics and research tools, few life sciences technologies hold more promise than genome-editing proteins— molecules that can be programmed to alter specific genes to treat or perhaps cure genetic diseases.
Professor David Sinclair has some complaints about the human lifespan. It’s too short, for a start. But, “it doesn’t have to be this way,” he told an audience on Monday.
A group of scientists has fused the power of statistical physics and artificial intelligence into a mathematical toolkit that can turn cancer-mutation data into multidimensional models that show how specific mutations alter the social networks of proteins in cells.
Forty million people worldwide are living with Alzheimer’s and this is only set to increase. But tiny brains grown in culture could help scientists learn more about this mysterious disease– and test new drugs.
Mimicking natural evolution in a test tube, scientists have devised an enzyme with a unique property that might have been crucial to the origin of life on Earth. The achievement is also likely to yield a powerful tool for evolving new and useful molecules.
Two major genetic studies of autism have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms.
A new breakthrough could help kidney stone sufferers get an exact diagnosis and specific treatment after genetic links to the condition were identified.
Should every newborn baby girl be genetically screened for breast-cancer risk? That isn’t cost-effective— yet. But if it were, would it be worthwhile? A previous study said no. But, new research suggests otherwise.
Researchers have sequenced the genome of enterovirus D68 sampled from patients treated at St. Louis Children’s Hospital. Nationwide, the virus has spread rapidly in recent months.
A new study has allowed researchers to peer into unexplored regions of the genome and understand for the first time the role played by more than 250 genes key to cell growth and development.
When tissues are deprived of blood, as happens during a stroke or heart attack, the lack of oxygen can cause serious damage. A new study shows that surprisingly, a DNA-repair enzyme called Aag actually makes this damage worse.
Scientists have discovered an algae virus never before seen in the throats of healthy people that may subtly alter a range of cognitive functions including visual processing and spatial orientation in those who harbor it.
Starting Monday, millions of people who have avoided colon cancer screening can get a new home test that's noninvasive and doesn't require the icky preparation most other methods do. The test is the first to look for cancer-related DNA in stool.
A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients.
Researchers have uncovered the genes that are normally activated during recovery from bacterial infection. The finding could lead to ways to jumpstart this recovery process and possibly fend off autoimmune diseases and chronic inflammatory disorders.