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Risk of Brain Injury is Genetic

May 19, 2014 1:03 pm | News | Comments

Premature babies’ risk of brain injury is influenced by their genes, a new study suggests. The researchers have identified a link between injury to the developing brain and common variation in genes associated with schizophrenia and the metabolism of fat.

Interactions May Matter Most for Longevity

May 16, 2014 10:48 am | News | Comments

If studying a single gene or a diet that might extend longevity is like searching for a fountain of youth, then a new study calls for looking at something more like the whole watershed. Brown University biologists who experimentally throttled three such factors in fruit flies found that lifespan depended more on interactions among the factors than on the factors themselves.

Breaking News: Genes May Verify Earliest American Inhabitants

May 15, 2014 2:12 pm | News | Comments

A new study uses genetic information extracted from the remains of an adolescent girl to help resolve the longstanding debate about the origins of the first people to inhabit the Americas.                  

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Researchers ID Gene That Causes Obesity-related Metabolic Syndrome

May 15, 2014 11:05 am | News | Comments

New research has identified a genetic mutation responsible for the cluster of cardiovascular risk factors that comprise the obesity-related metabolic syndrome.                          

Breastfeeding May Lower Ovarian Cancer Risk in Women with BRCA Mutations

May 14, 2014 12:50 pm | News | Comments

Breastfeeding, tubal ligation– also known as having one’s “tubes tied”– and oral contraceptives may lower the risk of ovarian cancer for some women with BRCA gene mutations, according to a new comprehensive analysis.          

It’s All in the Genes, but Whose?

May 13, 2014 1:12 pm | News | Comments

Researchers argue that biologists trying to explain the connection between genotype and phenotype need to consider yet another factor: genetic material that doesn’t come from an organism’s chromosomes at all.            

Breaking News: Genetic Marker Linked to OCD

May 13, 2014 9:11 am | News | Comments

A group of researchers say they have identified a genetic marker that may be associated with the development OCD, the causes and mechanisms of which are some of the least understood among mental illnesses.            

Atlas Shows How Genes Affect Our Metabolism

May 12, 2014 2:10 pm | News | Comments

In the most comprehensive exploration of the association between genetic variation and human metabolism, researchers have provided unprecedented insights into how genetic variants influence complex disease and drug response through metabolic pathways. The team has linked 145 genetic regions with more than 400 molecules involved in human metabolism in human blood.

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Immune Therapy Might be Effective for Multiple Myeloma

May 12, 2014 1:32 pm | News | Comments

A new study provides evidence that genetically modifying immune cells might effectively treat multiple myeloma, a disease that remains incurable and will account for an estimated 24,000 new cases and 11,100 deaths in 2014.        

Autism-related Protein Plays Vital Role in Addiction

May 12, 2014 1:19 pm | Videos | Comments

Investigators report that a gene essential for normal brain development, and previously linked to Autism Spectrum Disorders, also plays a critical role in addiction-related behaviors.                   

Expanding the Power of RNA Interference

May 12, 2014 1:12 pm | News | Comments

Using nanoparticles designed and screened for endothelial delivery of short strands of RNA called siRNA, researchers were able to target RNAi to endothelial cells, which form the linings of most organs. This raises the possibility of using RNAi to treat many types of disease.

Man's Best Friend Shares Similar 'Albino' Gene

May 12, 2014 1:05 pm | News | Comments

Researchers have identified a genetic mutation in Doberman pinschers that causes albinism in the breed, a discovery that has eluded veterinarians and breeders worldwide up until now.                   

Dopamine Turns Worker Ants into Warrior Queens

May 12, 2014 12:51 pm | News | Comments

The ritualized fighting behavior of one ant species is linked to increases in dopamine levels that trigger dramatic physical changes in the ants without affecting their DNA. The researchers studied Indian jumping ants (Harpegnathos saltator), which can undergo significant changes in physiology without any related changes to their DNA. Instead, the changes depend on which genes are turned on or off.

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Newly Discovered Gene Linked to Esophageal Cancer

May 9, 2014 1:39 pm | News | Comments

A newly discovered gene linked to esophageal cancer holds the promise of new treatments for up to 15 percent of the 8,500 people diagnosed with esophageal cancer in the UK every year.                  

Microarray for Research into Haematological and Solid Cancers

May 9, 2014 1:18 pm | Product Releases | Comments

Oxford Gene Technology (OGT) released a new microarray designed to improve the accuracy and efficiency of cancer research. The CytoSure Cancer +SNP array (4x180k) combines long oligo array comparative genomic hybridisation (aCGH) probes with fully validated single nucleotide polymorphism (SNP) content.

Better Cognition Seen with Gene Carried by 1 in 5 People

May 9, 2014 12:56 pm | Videos | Comments

A scientific team has discovered that a common form of a gene already associated with long life also improves learning and memory, a finding that could have implications for treating age-related diseases like Alzheimer’s.         

Cancer-focused Array for Malignancies, Tumors

May 8, 2014 2:02 pm | Product Releases | Comments

Oxford Gene Technology (OGT) offers the CytoSure Consortium Cancer +SNP array (4x180k). The array allows the simultaneous detection of copy number variation (CNV) and loss of heterozygosity (LOH), with a SNP resolution that enables reporting of LOH at 10Mb.

Mapping the Spider Genome

May 7, 2014 1:33 pm | News | Comments

For the first time, a group of Danish and Chinese researchers has sequenced the genome of the spider. This knowledge provides a much more qualified basis for studying features of the spider. It also shows that humans share certain genomic similarities with spiders.

Starting Signal for Antiviral Defense

May 7, 2014 1:21 pm | News | Comments

Cells have to protect themselves against damage in their genetic material for one thing, but also against attack from the outside, by viruses for example. They do this by using different mechanisms: special proteins search out and detect defects in the cell's own DNA, while the immune system takes action against intruders. Scientists have now shown that the two protective mechanisms are linked by a shared protein.

Detecting Fetal Chromosomal Defects Without Risk

May 7, 2014 12:21 pm | News | Comments

Chromosomal abnormalities that result in birth defects and genetic disorders remain a significant health burden, as some prenatal screenings are a potential risk to mother and unborn child. Now, scientists are investigating a new sequencing procedure that can be completed without harm to mother or fetus.

Genetic Risk Factor for Premature Birth Found

May 6, 2014 1:44 pm | News | Comments

Researchers at the University of California, San Diego School of Medicine have discovered a genetic risk factor for premature birth. The risk factor is related to a gene that codes for a protein that the scientists have found helps the body’s immune cells recognize and fight Group B Streptococcus (GBS) bacteria.

Microarray Scanner for in vitro Diagnostics

May 5, 2014 1:54 pm | Product Releases | Comments

The SureScan Dx from Agilent Technologies Inc. is a microarray scanner indicated for use in a clinical laboratory environment when measuring fluorescence signals of labeled DNA or RNA targets hybridized to microarrays used as part of a validated diagnostic assay.

Immune System Linked to Neurodegeneration

May 5, 2014 11:56 am | News | Comments

Researchers have demonstrated how genetic variations among healthy, young individuals can influence immune cell function. Many of those variants are also genetic risk factors for common diseases later in life, offering new insight into disease pathology.

30-year Puzzle in Breast Cancer Solved

May 2, 2014 1:29 pm | News | Comments

Scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer. CTCF is a very well-studied DNA binding protein that exerts a major influence on the architecture of the human genome, but had not been previously linked to cancer.

Automated Next Generation Sequencing Applications

May 1, 2014 2:21 pm | Product Releases | Comments

Beckman Coulter Life Sciences, through a partnership with Illumina, offers automated methods to improve processes and throughput in next generation sequencing (NGS) sample preparation. Under the agreement, Beckman Coulter will use its experience in automated NGS sample preparation to develop, distribute and support automation for Illumina’s TruSeq and Nextera sample preparation kits and Illumina will provide technical expertise on chemistry and protocols.

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