The thousands of mitochondrial DNA (mtDNA) molecules present in each cell are known primarily for their role converting food and oxygen into energy. But Yale researchers have identified an unexpected relationship between mtDNA and the innate immune response.
Britain's House of Commons gave preliminary approval to permitting scientists to create babies from the DNA of three people, a technique that could protect some children from inheriting potentially fatal diseases from their mothers. Read more...
New research could lead to a better understanding of how the brain works in people with autism.
President Obama held a press conference revealing new details surrounding the Precision Medicine initiative he announced during the State of The Union.
Researchers have begun to appreciate the importance of copy number variation when considering the connections between DNA and disease.
For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a major role in ALS pathology.
For people with pancreatitis, a noncancerous inflammation of the tiny ducts in the 6-inch organ, the discomfort can be devastating.
People who carry a variant of a gene that is associated with longevity also have larger volumes in a front part of the brain involved in planning and decision-making, according to researchers at UC San Francisco.
Cells are incredibly complicated machines with thousands of interacting parts — and disruptions to any of those interactions can cause disease.
Killer T cells are one of the body's main lines of defense against pathogens.
Tuberculosis affects over 12 million people globally, and is usually treated with a course of four drugs over several months.
Scientists have determined how an enzyme essential for energy metabolism functions.
Millions of genetically modified mosquitoes could be released in the Florida Keys if British researchers win approval to use the bugs against two extremely painful viral diseases.
By now, most everyone has seen videos all over social media of friends and family dousing themselves in ice cold water as part of the ALS Ice Bucket Challenge.
A team of scientists based at Brown University has found that reducing expression of a fundamentally important gene called Myc significantly increased the healthy lifespan of laboratory mice, the first such finding regarding this gene in a mammalian species.
A new procedure can quickly and efficiently increase the length of human telomeres, the protective caps on the ends of chromosomes that are linked to aging and disease.
A new study has shown for the first time why protein mutations lead to the familial form of Parkinson’s disease.
The President briefly mentioned the project during the State of The Union earlier this week.
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have produced an approach that protects animal models against a type of genetic disruption that causes intellectual disability, including serious memory impairments and altered anxiety levels.
Researchers at the University of California, San Diego School of Medicine, with collaborators in Korea and Scotland, have identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma.
The drugs were designed to keep cancer cells at bay by preventing their growth, survival and spread. Yet, after clinical trials, they left scientists scratching their heads and drug developers watching their investments succumb to cancer’s latest triumph.
Scientists are unraveling a mystery behind a fairly common disease that leads to heart failure: Why do some people with a key mutated gene fall ill while others stay healthy? Researchers tested more than 5,200 people to tease apart when mutations really are harmful or are just bystanders.
Fibrosis is a constant feature of all chronic liver diseases.
Researchers have found a possible predictor for little understood -- but often disabling or even fatal -- stroke complications.
When 2 milliliters of blood are run through the chip, the tumor cells stick to the nanowires like Velcro.