Researchers have identified a previously unknown process that many bacteria, including those that cause disease in humans, use to survive. Their discovery could lead to new therapies for bacterial infections like MRSA and tuberculosis that are resistant to current antibiotic treatments.
Transcription, the process in which genetic information from DNA is copied into RNA to produce proteins, requires many pieces coming together.
Investigators administered a customized genetic construct consisting of tiny rings of DNA, called DNA minicircles, to mice.
A massive worldwide analysis of genetic data from almost 340,000 people around the world has brought understanding of the genetic basis of obesity a step closer.
Like a stealth jet cloaks itself from radar, cancer cells cloak themselves within tumors by hiding behind a dense layer of cellular material known as stroma.
The size of the human brain expanded dramatically during the course of evolution, imparting us with unique capabilities to use abstract language and do complex math. But how did the human brain get larger than that of our closest living relative, the chimpanzee, if almost all of our genes are the same?
Using advanced DNA sequencing methods, researchers have identified a new gene that is associated with sporadic amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease.
23andMe, Inc., the leading personal genetics company, today announced that it has been granted authority by the U.S. Food and Drug Administration (FDA) to market the first direct-to-consumer genetic test under a regulatory classification for novel devices.
Single-letter genetic variations within parts of the genome once dismissed as ‘junk DNA’ can increase cancer risk through 'wormhole-like' effects on far-off genes, new research shows.
Using antibodies from camels and alpacas, scientists have found a way to deliver anticancer viruses directly to tumor cells, leaving other types of cells uninfected.
Nanometer-sized “drones” that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis.
Our hearing has a secret bodyguard: a newly discovered connection from the cochlea to the brain that warns of intense incoming noise that causes tissue damage and hearing loss.
Much like mapping the human genome laid the foundations for understanding the genetic basis of human health, new maps of the human epigenome may further unravel the complex links between DNA and disease. The epigenome is part of the machinery that helps direct how genes are turned off and on in different types of cells.
Bacteria are most familiar through their roles in harmful infections. But scientists have realized that such bacteria are only a tiny fraction of the bacterial communities that live in and on our bodies. Most bacteria are commensal, which means they do not cause harm and often confer benefits.
Findings advance efforts to identify who would benefit from more aggressive therapy at earliest stages.
A molecule that can block the progress of Alzheimer’s disease at a crucial stage in its development has been identified by researchers in a new study, raising the prospect that more such molecules may now be found.
A MIT researcher wants to bring advances in drug delivery and biomaterials to the clinic.
Cells lining the intestinal tract form a critical barrier, protecting our bodies from the billions of bacteria living in the gut.
The Human Genome Project wrapped up over a decade ago, yet around a third of the genome remains mysterious, its function unknown.
Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into a new variant of the virus.
Microbes, small and ancient life forms, play a key role in maintaining life on Earth. As has often been pointed out, without microbes, we’d die—without us, most microbes would get along just fine.
This accelerated life cycle is a necessity when one makes one’s home in seasonal ponds that regularly evaporate, and the fact that the fish shares many biological characteristics with humans makes it a promising candidate for the study of aging and longevity. But until now, scientists didn’t have the necessary tools and information with which to conduct genetic studies.
Most of the genetic mutations that cause cancer result from environmental ‘damage’ (for example, through smoking or as a result of over-exposure to sunlight) or from spontaneous errors as cells divide.
Mice genetically deficient in serotonin—a crucial brain chemical implicated in clinical depression—are more vulnerable than their normal littermates to social stressors, according to a Duke study appearing this week in the Proceedings of the National Academy of Sciences.
Scientists at The Scripps Research Institute (TSRI) have identified a new cellular pathway that is affected in cystinosis, a rare genetic disorder that can result in eye and kidney damage.