A molecule that can block the progress of Alzheimer’s disease at a crucial stage in its development has been identified by researchers in a new study, raising the prospect that more such molecules may now be found.
A MIT researcher wants to bring advances in drug delivery and biomaterials to the clinic.
Cells lining the intestinal tract form a critical barrier, protecting our bodies from the billions of bacteria living in the gut.
The Human Genome Project wrapped up over a decade ago, yet around a third of the genome remains mysterious, its function unknown.
Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into a new variant of the virus.
Microbes, small and ancient life forms, play a key role in maintaining life on Earth. As has often been pointed out, without microbes, we’d die—without us, most microbes would get along just fine.
This accelerated life cycle is a necessity when one makes one’s home in seasonal ponds that regularly evaporate, and the fact that the fish shares many biological characteristics with humans makes it a promising candidate for the study of aging and longevity. But until now, scientists didn’t have the necessary tools and information with which to conduct genetic studies.
Most of the genetic mutations that cause cancer result from environmental ‘damage’ (for example, through smoking or as a result of over-exposure to sunlight) or from spontaneous errors as cells divide.
Mice genetically deficient in serotonin—a crucial brain chemical implicated in clinical depression—are more vulnerable than their normal littermates to social stressors, according to a Duke study appearing this week in the Proceedings of the National Academy of Sciences.
Scientists at The Scripps Research Institute (TSRI) have identified a new cellular pathway that is affected in cystinosis, a rare genetic disorder that can result in eye and kidney damage.
A vial of rare snake venom refused to give up its secret formula for lethality; its toxins had no effect on the proteins that most venoms target.
Ebola has claimed nearly 9,000 lives in West Africa over the past year, although new infections have dropped dramatically in recent months.
Next-generation sequencing (NGS) technology can now profile highly damaged DNA samples that contain 75 percent less base-pair information, compared with previous systems. This is a significant improvement for law enforcement in cases involving missing persons or unidentified human remains.
MicroRNA are the tiny non-coding RNA molecules that help determine whether genes are expressed or silenced.
Scientists have developed a potential new therapy based on an unlikely model: immune molecules from cows.
Researchers have revealed new insights into possible ways to vaccinate people to generate potent antibodies of the type that are predicted to offer protection against diverse strains of the highly mutable HIV.
Several state legislatures are debating vaccine-related measures as dozens of people have fallen ill from a measles outbreak that started at Disneyland in December and spread beyond the theme park.
A team of researchers are working on a diagnostic machine that can detect Ebola virus and other dangerous microbes.
Researchers said they can tell who will become depressed or anxious in response to stressful life events, as far as four years down the road.
Scientists have found diverse genomic changes in single neurons from the brains of Alzheimer’s patients, pointing to an unexpected factor that may underpin the most common form of the disease.
A preliminary study suggests stem cell transplantation may reverse disability and improve quality of life for patients with relapsing-remitting multiple sclerosis.
Humans have fewer remnants of viral DNA in their genes compared to other mammals.
Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but it’s very difficult to effectively deliver toxic or missing genes to cancer cells in the brain.
Oxford Gene Technology (OGT) offers the CytoSure Consortium Cancer +SNP array (4x180k). The array allows the simultaneous detection of copy number variation (CNV) and loss of heterozygosity (LOH), with a SNP resolution that enables reporting of LOH at 10Mb.
Researchers have determined that two mutations on a single gene can interact in a way that lowers the carrier's risk for a heart attack. The variants are found in a gene called DBH, which regulates an enzyme involved in the conversion of dopamine to norepinephrine - both of which are important chemical messengers and hormones.