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The Lead

Why Protein Mutations Lead to Parkinson's Disease

January 22, 2015 4:29 pm | by UCSD | News | Comments

A new study has shown for the first time why protein mutations lead to the familial form of Parkinson’s disease.                         

The Ups and Downs of the Seemingly Idle Brain

January 21, 2015 9:16 am | by Brown University | News | Comments

A new study probed deep into this somewhat mysterious cycle in mice, to learn more about how the...

Watching How Cells Interact

January 13, 2015 3:24 pm | by Anne Trafton, MIT | News | Comments

A new device offers a much more detailed picture of cellular communication.   ...

Radiation, Hormone Therapy Prolong Survival for Older Men With Prostate Cancer

January 7, 2015 4:30 pm | by University of Pennsylvania | News | Comments

Adding radiation treatment to hormone therapy saves more lives among older men with locally...

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Trying for Test-Tube Baby? Risks to Mom Are Rare

January 7, 2015 4:01 pm | by Lindsey Tanner - AP Medical Writer | News | Comments

A new 12-year U.S. study shows the most frequent involve drugs used to stimulate ovaries, but it suggests problems are rarely fatal.                      

Nestlé Health Science Invests $65M in Microbiome Therapy Startup

January 6, 2015 12:01 pm | News | Comments

The investment made by Nestle Health Science, a subsidiary of Nestle, will help fund the next stage of development for the startup's CDI treatment.                   

Enzyme's Alter Ego Helps Activate Helps Activate the Immune System

December 29, 2014 5:08 pm | by Johns Hopkins University | News | Comments

These findings could shed light on related Alzheimer's protein.                                 

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Protein Identified as Possible Therapy Target for Viral and Bacterial Infections

December 29, 2014 4:39 pm | by Virginia Commonwealth University | News | Comments

A protein could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, Influenza, Hepatitis and superbug bacteria.                   

Scientists Create Precursor to Human Egg and Sperm

December 26, 2014 9:24 am | by University of Cambridge | News | Comments

Scientists have created primordial germ cells – cells that will go on to become egg and sperm – using human embryonic stem cells.                      

Researchers Shed Light on How 'Microbial Dark Matter' May Cause Disease

December 24, 2014 9:20 am | by UCLA | News | Comments

One of the great recent discoveries in modern biology was that the human body contains 10 times more bacterial cells than human cells. But much of that bacteria is still a puzzle to scientists.           

New Technology Makes Tissues, Someday Makes Organs

December 22, 2014 4:31 pm | by Brown University | News | Comments

A new instrument could someday build replacement human organs the way electronics are assembled today: with precise picking and placing of parts.                   

Serotonin Neuron Subtypes

December 18, 2014 4:37 pm | by Stephanie Dutchen, Harvard Medical School | News | Comments

Neuroscientists have proposed that brain cells come in different subtypes that have different properties and responsibilities.                     

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New Findings Demonstrate Effective Treatment for Diabetes Patients

December 18, 2014 4:23 pm | by University of Pennsylvania | News | Comments

Scientists have found a new way to help Type 1 diabetes patients defend themselves against life-threatening low blood sugar.                       

Gene-Editing Guide

December 17, 2014 4:42 pm | by Sue McGreevy, Harvard University | News | Comments

Investigators have developed a method for detecting unwanted DNA breaks—across the entire genome of human cells—induced by the popular gene-editing tools called CRISPR-Cas RNA-guided nucleases (RGNs).          

Scientists Open New Frontier of Vast Chemical 'Space'

December 17, 2014 4:20 pm | News | Comments

Chemists at The Scripps Research Institute have invented a powerful method for joining complex organic molecules that is extraordinarily robust.                    

Rio Organizers Create 'Super Bacteria' Task Force

December 17, 2014 2:47 pm | by Jenny Barchfield - Associated Press - Associated Press | News | Comments

Brazilian organizers of the 2016 Olympics are creating a task force to deal with a so-called "super bacteria" discovered in Olympic sailing waters.                   

Researchers Develop Improved Means of Detecting Mismatched DNA

September 16, 2014 2:48 pm | News | Comments

Researchers have identified a highly sensitive means of analyzing very tiny amounts of DNA. The discovery, they say, could increase the ability of forensic scientists to match genetic material in some criminal investigations.       

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Method Developed to Determine Fingerprint Comparison Difficulty

May 7, 2014 11:52 am | News | Comments

Fingerprint examination, though in use for more than 100 years, has until recently undergone surprisingly little scientific scrutiny. Now, a newly published paper provides important new insight into what specific, visual aspects of fingerprint pairs make their analysis more or less difficult.

Predicting Human Body Height from DNA is 'Feasible'

November 20, 2013 12:16 pm | News | Comments

Despite large international efforts to catalogue the genes that influence the stature of humans, knowledge on genetic determinants of adult body height is still incomplete. Now, DNA-based prediction of taller-than-average body height is feasible, as reported by researchers.

British Cat DNA Database Helps Convict Killer

August 14, 2013 1:22 pm | by RAPHAEL SATTER - Associated Press - Associated Press | News | Comments

Fingerprints are not the only thing that killers can leave behind — add cat hair to that list. A British university said that its DNA database of British felines helped convict a man of manslaughter, illustrating how the genetic material of pets can be used by crime scene investigators.

DNA Forensics Tracks Dual Genomes in Melanoma

July 16, 2013 10:24 am | News | Comments

A new study reports the first proof of cancer’s ability to fuse with blood, giving cancer the ability to travel and seeding sites of metastasis around the body. The work used DNA fingerprinting of a bone marrow transplant patient with cancer, along with DNA fingerprinting of the patient’s bone marrow donor, to show that metastatic cancer cells carried parts of both genomes, fused together into a hybrid cancer cell.

Smartphones Become Handheld Biosensors

May 24, 2013 9:43 am | News | Comments

Researchers and physicians in the field could soon run on-the-spot tests for environmental toxins, medical diagnostics, food safety and more with their smartphones. Researchers have developed a cradle and app for the iPhone that uses the phone’s built-in camera and processing power as a biosensor to detect toxins, proteins, bacteria, viruses and other molecules.

Researcher Invents 'DNA Bardcode'

May 1, 2013 9:13 am | News | Comments

DNA evidence is invisible and remarkably easy to transfer, making it possible for a sample to be spilled or even planted on a piece of evidence. A researcher has developed a solution that permanently marks DNA samples to prevent contamination. 

Providing Closure

April 5, 2013 10:25 am | by Robert Fee | Life Technologies Corporation | Articles | Comments

For 42 years, Muammar Gaddafi ran a ruthless regime in Libya. Although deposed in 2011, one of his sad legacies is a series of mass graves containing an estimated 20,000 human remains. But with this discovery comes a chance to solve decades-old missing person cases. Using forensic DNA identification technologies, scientists employed by the Libyan government will soon begin this process. But first they need the tools and the training.

Forensic Assay Approved for NDIS

February 5, 2013 2:25 pm | Product Releases | Comments

The Promega PowerPlex Y23 System is now approved for use in laboratories that generate DNA records for the National DNA Index System (NDIS). The PowerPlex Y23 System is a rapid human identification Y-chromosome short tandem repeat (Y-STR) assay for forensic casework, offender databasing, and relationship testing.

Aztec Conquest Altered Genetics among Early Mexico Inhabitants, New DNA Study Shows

January 31, 2013 11:25 am | News | Comments

For centuries, the fate of the original Otomí inhabitants of Xaltocan, the capital of a pre-Aztec Mexican city-state, has remained unknown. Researchers have long wondered whether they assimilated with the Aztecs or abandoned the town altogether. According to new anthropological research, the answers may lie in DNA.

Scientists seek to solve mystery of Piltdown Man

December 14, 2012 2:02 pm | by JILL LAWLESS - Associated Press - Associated Press | News | Comments

It was an archaeological hoax that fooled scientists for decades. A century on, researchers are determined to find out who was responsible for Piltdown Man, the missing link that never was. Speculation about who did it rages to this day. Now scientists are marking the anniversary with a new push to settle the argument for good.

Faster and More Efficient Forensics

July 12, 2011 11:44 am | by Mike May | Articles | Comments

Increasing pressure requires labs to find ways to do more with less—analyze more DNA and do so faster and at less expense. To reach those goals, forensics labs need new tools that help them collect more samples, analyze them at higher throughout, and also churn out more accurate results.

Top Trends in Life Science: Biocompatibility

June 10, 2010 8:40 am | Articles | Comments

One of the overarching trends for Life Sciences has been the need for biocompatible materials and processes. For analytical and diagnostic systems, the word biocompatibility refers to the interaction between any component in the system and the biological sample

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