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Mouse Brains Mapped in Greatest Detail Yet

April 29, 2013 10:44 am | News | Comments

Hopes for a cure for many brain diseases may rest on the humble mouse, now that scientists can map the rodents' brains more thoroughly than ever before. Researchers have created the most detailed atlas of the mouse brain, a development that is helping in the fight against brain disease.

Hormone is Potential Diabetes Breakthrough

April 25, 2013 12:47 pm | by Harvard Medical School | News | Comments

Researchers have discovered a hormone that holds promise for a dramatically more effective treatment of type 2 diabetes, a metabolic illness afflicting an estimated 26 million Americans. The researchers believe that the hormone might also have a role in treating type 1, or juvenile, diabetes.

Video Reveals How Drugs Kill Cancer

April 25, 2013 10:14 am | News | Comments

Scientists have discovered why a particular cancer drug is so effective at killing cells. Their findings could be used to aid the design of future cancer treatments. Using high-powered laser-based microscopes, researchers made videos of the process by which rituximab binds to a diseased cell and then attracts white blood cells known as natural killer (NK) cells to attack.

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Novel Therapy Safe for ALS

April 24, 2013 9:24 am | News | Comments

An investigational treatment for an inherited form of Lou Gehrig’s disease has passed an early phase clinical trial for safety, researchers report. The researchers have shown that the therapy produced no serious side effects in patients with the disease, also known as amyotrophic lateral sclerosis (ALS). The phase 1 trial’s results also demonstrate that the drug was successfully introduced into the central nervous system.

Gone, But Not Forgotten

April 23, 2013 12:16 pm | News | Comments

An international team of neuroscientists has described for the first time in exhaustive detail the underlying neurobiology of an amnesiac who suffered from profound memory loss after damage to key portions of his brain. In a new paper, researchers recount the case of EP, a man who suffered radical memory loss and dysfunction following a bout of viral encephalitis.

Finding the Needle in a Haystack

April 22, 2013 12:13 pm | News | Comments

A contact lens on the bathroom floor, an escaped hamster in the backyard, a car key in a bed of gravel: How are we able to focus so sharply to find that proverbial needle in a haystack? Scientists ave discovered that when we embark on a targeted search, various visual and non-visual regions of the brain mobilize to track down a person, animal or thing.

Food Poisonings Up from Raw Milk, Poultry Bacteria

April 18, 2013 12:09 pm | by MIKE STOBBE - AP Medical Writer - Associated Press | News | Comments

Health officials are seeing more food poisonings caused by a bacteria commonly linked to raw milk and poultry. A study released Thursday said campylobacter cases grew by 14 percent over the last five years. The Centers for Disease Control and Prevention report was based on  foodborne infections in only 10 states- about 15 percent of the American population.

Memory Loss Reversed in Animal Brains

April 18, 2013 11:09 am | News | Comments

Neuroscientists have taken a major step in their efforts to help people with memory loss tied to brain disorders such as Alzheimer’s disease. Using sea snail nerve cells, the scientists reversed memory loss by determining when the cells were primed for learning.

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Acute Stress is Good for the Brain

April 17, 2013 11:42 am | News | Comments

Overworked and stressed out? Look on the bright side: Some stress is good for you. New research has uncovered exactly how acute stress– short-lived, not chronic– primes the brain for improved performance. In studies on rats, researchers found that significant, but brief stressful events caused stem cells in their brains to proliferate into new nerve cells.

Decoding the Structure of Bone

April 17, 2013 10:28 am | News | Comments

The bones that support our bodies are made of remarkably complex arrangements of materials— so much so that decoding the precise structure responsible for their great strength and resilience has eluded scientists’ best efforts for decades. But now, a team of researchers has finally unraveled the structure of bone with almost atom-by-atom precision.

Breast Cancer Treatment Improved by Nanodiamonds

April 16, 2013 10:55 am | News | Comments

Recently, doctors have begun to categorize breast cancers into four main groups according to the genetic makeup of the cancer cells. Which category a cancer falls into generally determines the best method of treatment. But cancers in one of the four groups— called "basal-like" or "triple-negative" breast cancer (TNBC)— have been particularly tricky to treat because they usually don't respond to the "receptor-targeted" treatments.

Next-gen Sequencing Finds Brain Tumor Mutations

April 15, 2013 11:02 am | News | Comments

Researchers have identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients. Researchers also found evidence the tumors are susceptible to drugs already in development. The study focused on a family of brain tumors known as low-grade gliomas (LGGs).

3-D Structure of Telomerase Enzyme Mapped

April 12, 2013 10:58 am | News | Comments

Like finally seeing all the gears of a watch and how they work together, researchers have, for the first time ever, solved the puzzle of how the various components of an entire telomerase enzyme complex fit together and function in a three-dimensional structure.

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Doctors Can ‘See’ Pain

April 10, 2013 5:02 pm | by MARILYNN MARCHIONE - AP Chief Medical Writer - Associated Press | News | Comments

In a provocative new study, scientists reported Wednesday that they were able to “see” pain on brain scans and, for the first time, measure its intensity and tell whether a drug was relieving it. Though the research is in its early stages, it opens the door to a host of possibilities.

Tiny Proteins Prevent Bacterial Gene Transcription

April 10, 2013 10:10 am | News | Comments

In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism. The road from gene to protein has an important stop along the way: ribonucleic acid, or RNA.

Safety Reflectors Reused in Bioterror Detection

April 10, 2013 9:49 am | News | Comments

Tiny versions of the reflectors on sneakers and bicycle fenders that help ensure the safety of runners and bikers at night are moving toward another role in detecting bioterrorism threats and diagnosing everyday infectious diseases, scientists said.

Green Coffee Beans Linked to Diabetic Control

April 9, 2013 12:52 pm | News | Comments

Scientists described evidence that natural substances extracted from unroasted coffee beans can help control the elevated blood sugar levels and body weight that underpin type 2 diabetes. Their presentation on chlorogenic acids― widely available as a dietary supplement was part of the 245th National Meeting and Exposition of the American Chemical Society (ACS).

Genetic Markers ID Second Alzheimer’s Pathway

April 5, 2013 10:32 am | News | Comments

Researchers have identified a new set of genetic markers for Alzheimer’s that point to a second pathway through which the disease develops.

Providing Closure

April 5, 2013 10:25 am | by Robert Fee | Life Technologies Corporation | Articles | Comments

For 42 years, Muammar Gaddafi ran a ruthless regime in Libya. Although deposed in 2011, one of his sad legacies is a series of mass graves containing an estimated 20,000 human remains. But with this discovery comes a chance to solve decades-old missing person cases. Using forensic DNA identification technologies, scientists employed by the Libyan government will soon begin this process. But first they need the tools and the training.

The Great Clamping Debate

April 4, 2013 11:40 am | by Cynthia Fox | Articles | Comments

Most of us born after 1960 have missed out on what was, since ancient times, “mankind’s first stem cell transplant.” For umbilical cords of most born after 1960 were—are—clamped right after birth. This denied us a last blast of stem-cell rich placenta blood, 40% of our circulation, before our first breath.

Obama Proposes $100M For Brain Mapping Project

April 3, 2013 8:50 am | by NEDRA PICKLER AND MALCOLM RITTER | News | Comments

President Barack Obama on Tuesday proposed an effort to map the brain's activity in unprecedented detail, as a step toward finding better ways to treat such conditions as Alzheimer's, autism, stroke and traumatic brain injuries.

Research Deciphers HIV Attack Plan

April 2, 2013 9:58 am | News | Comments

A new study defines previously unknown properties of transmitted HIV-1, the virus that causes AIDS.

Following the Body’s Own Prescription

April 1, 2013 10:22 am | by Cynthia Fox | Articles | Comments

An intuitive approach, which co-opts the body’s own molecular machinery, has led to massive expansions of umbilical cord blood cells. It and other new approaches “will revolutionize all transplantation,” says University of Minnesota Blood and Marrow Transplantation Director John Wagner.

Stem Cell Fate Depends on ‘Grip’

March 29, 2013 10:52 am | News | Comments

A team of researchers has generated new insight on how a stem cell’s environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can “grip” the material they are growing in.

Common Foods Cause DNA Damage

March 28, 2013 9:35 am | News | Comments

In a laboratory study pairing food chemistry and cancer biology, scientists tested the potentially harmful effect of foods and flavorings on the DNA of cells. They found that liquid smoke flavoring, black and green teas and coffee activated the highest levels of a well-known, cancer-linked gene called p53.

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