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The Lead

Half-Billion-Year-Old Heart Found More Complex than Today’s

April 24, 2014 3:01 pm | by Cynthia Fox | Articles | Comments

520 million years ago, the first known animal heart, the heart of an ancient shrimp, was formed. Now, it, and its vascular system, have been found to be more complex than that of modern shrimp, researchers report.         

Boring Cells Could Hold the Key to Heart Disease

April 24, 2014 1:47 pm | News | Comments

Fibroblasts could offer an alternative to heart transplants for patients with heart disease....

Ultrasound Device May Help Detect Risk for Heart Attack, Stroke

April 24, 2014 1:31 pm | News | Comments

Researchers have developed an ultrasound device that could help identify arterial plaque that is...

Breast Cancer Replicates Brain Development Process

April 24, 2014 1:12 pm | News | Comments

New research reveals that a process that forms a key element in the development of the nervous...

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Gene Determines If Aspirin Can Lower Colon Cancer Risk

April 24, 2014 1:00 pm | News | Comments

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene.     

Breaking News: New Genetic Brain Disorder Discovered

April 24, 2014 12:09 pm | News | Comments

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, has been reported.                       

Gene Therapy May Boost Cochlear Implants

April 23, 2014 3:21 pm | by Lauran Neergaard - AP Medical Writer | News | Comments

Australian researchers have combined cochlear implants with gene therapy in an experiment that improves the hearing of deafened animals. Cochlear implants partially restore hearing by emitting electrical impulses that activate auditory nerves in the brain.

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Triclosan Spurs Growth of Breast Cancer Cells

April 23, 2014 1:01 pm | News | Comments

Some manufacturers are turning away from using triclosan as an antimicrobial ingredient in soaps, toothpastes and other products over health concerns. Now, scientists are reporting new evidence that appears to support these worries.     

Scientists ID New Protein Complex Involved in Learning, Memory

April 23, 2014 12:57 pm | News | Comments

Scientists have identified a protein complex, a novel role for a protein known as RGS7, that plays a critical but previously unknown role in learning and memory formation.                       

MRI Sensor Tracks Oxygen in the Body

April 23, 2014 12:49 pm | News | Comments

Measuring tumors’ oxygen levels could help doctors make decisions about treatments, but there’s currently no reliable, noninvasive way to make such measurements. However, a new an injectable device that reveals oxygen levels over several weeks could change that.

Enzymes Can Help Fix Cancer-causing DNA Defects

April 23, 2014 12:40 pm | News | Comments

Researchers have identified an important enzyme pathway that helps prevent new cells from receiving too many or too few chromosomes, a condition that has been directly linked to cancer and other diseases.             

Cancer Spread’s ‘Family Tree’

April 23, 2014 12:34 pm | News | Comments

The process of metastasis is still poorly understood. Now, a research team has developed a simple test that can reveal the evolutionary relationships among various tumor sites within a patient, information that may someday help with treatment planning.

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Scientists Alter Fat Metabolism in Animals to Prevent Heart Disease

April 23, 2014 12:28 pm | News | Comments

Working with mice and rabbits, scientists have found a way to block abnormal cholesterol production, transport and breakdown, successfully preventing the development of atherosclerosis, the main cause of heart attacks and strokes and the number-one cause of death among humans.

Michigan Man Among First to Get 'Bionic Eye'

April 23, 2014 3:18 am | by Mike Householder - Associated Press | News | Comments

Diagnosed with retinitis pigmentosa as a teenager, Roger Pontz has been almost completely blind for years. Now, thanks to a high-tech procedure that involved the surgical implantation of a "bionic eye," he's regained enough of his eyesight to catch small glimpses of his wife, grandson and cat.

Killing Cancer on the Run

April 22, 2014 3:30 pm | by Skip Derra | Articles | Comments

A dream solution to cancer metastasis has been to develop a method that can track and kill the cancer cells that are on the move. The complexity at which those cancer cells operate has long been a formidable obstacle to stopping metastases, which cause 90 percent of cancer deaths, but that may change. 

Child’s Autism Risk Accelerates with Mother’s Age, Study Says

April 22, 2014 3:21 pm | News | Comments

Older parents are more likely to have a child who develops an autism spectrum disorder (ASD) than are younger parents, according to a recent study.                             

How the Body Fights Against Viruses

April 22, 2014 3:13 pm | News | Comments

Scientists have now shown how double stranded RNA, such as viral genetic information, is prevented from entering the nucleus of a cell. During the immune response against viral infection, the protein ADAR1 moves from the cell nucleus into the surrounding cytoplasm.

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CT Measures Potentially Dangerous Arterial Plaque in Diabetic Patients

April 22, 2014 3:04 pm | News | Comments

Imaging of the coronary arteries with computed tomography angiography provides an accurate assessment of arterial plaque and could have a dramatic impact on the management of diabetic patients who face a high risk of heart attacks and other cardiovascular events, according to a new study.

Fast Way to Measure DNA Repair

April 22, 2014 2:57 pm | News | Comments

A team of researchers has developed a test that can rapidly assess several DNA repair systems, which could help determine individuals’ risk of developing cancer and help doctors predict how a given patient will respond to chemotherapy drugs.   

Brain Size Matters in Animal Self-control

April 22, 2014 2:47 pm | Videos | Comments

Scientists collaborated on the first large-scale investigation into the evolution of self-control in animals, defined in the study as the ability to inhibit powerful but ultimately counter-productive behavior.            

Lab Turns Skin Cells into Human Airway Tissue

April 22, 2014 12:25 pm | News | Comments

Using reprogrammed skin cells, researchers have for the first time used stem cell techniques to grow fully functional assemblies of the cells that line airways leading to the lungs.                    

Brain Activity Observed in Real Time

April 22, 2014 12:14 pm | News | Comments

Scientists have worked together to create tools for observing nerves in living animals that signal between themselves in real time, which will help them understand how those individual signals add up to the complex collection of a person's thoughts and memories.

Breaking News: Sleep Disorder Linked to Brain Diseases

April 22, 2014 8:58 am | News | Comments

Researchers say that rapid-eye-movement sleep behavior disorder (RBD), which causes people to act out their dreams, is the best current predictor of brain diseases like Parkinson's and Alzheimer's.               

Muscle Weakness in Alcoholism Linked to Mitochondrial Repair Issues

April 21, 2014 2:49 pm | News | Comments

Muscle weakness from long-term alcoholism may stem from an inability of mitochondria, the powerhouses of cells, to self-repair, according to a new study. In the research, scientists found evidence that chronic heavy alcohol use affects a gene involved in mitochondrial repair and muscle regeneration.

'Molecular Tweezer' is a Step Toward Parkinson’s Treatment

April 21, 2014 2:43 pm | Videos | Comments

The most effective way to tackle debilitating diseases is to punch them at the start and keep them from growing. Research shows that a small “molecular tweezer” keeps proteins from clumping, the first step of disorders such as Parkinson’s disease, Alzheimer’s disease and Huntington’s disease.

Cancer Stem Cells Linked to Drug Resistance

April 21, 2014 2:25 pm | News | Comments

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers have discovered a biomarker called CD61 that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.

Scientists ID Source of Most Bladder Cancer Cases

April 21, 2014 2:15 pm | News | Comments

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers. This study is the first to pinpoint the normal cell type that can give rise to invasive bladder cancers.   

Turning Science on its Head

April 21, 2014 2:07 pm | News | Comments

Neuroscientists have made a discovery that turns 160 years of neuroanatomy on its head. Myelin, the electrical insulating material in the body long known to be essential for the fast transmission of impulses along the axons of nerve cells, is not as ubiquitous as thought, according to new work.

Ginseng Can Treat, Prevent Influenza

April 21, 2014 12:17 pm | News | Comments

Ginseng can help treat and prevent influenza and respiratory syncytial virus (RSV), a respiratory virus that infects the lungs and breathing passages, according to new research findings.                   

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