In a pair of landmark studies that exploit the genetic sequencing of the “missing link” cold virus, rhinovirus C, scientists have constructed a 3-D model of the pathogen that shows why there is no cure yet for the common cold.
For nearly 300 years, investigators have known that body temperature follows a circadian, or 24-hour, rhythm, with a peak during the day and a low at night. Now, researchers explain how body temperature rhythms are synchronized while maintaining the ability to adapt to changes in environmental temperature no matter the time of day or night.
Light enhances brain activity during a cognitive task even in some people who are totally blind, according to a new study. The findings contribute to scientists' understanding of everyone's brains, as they also revealed how quickly light impacts on cognition.
Studies presented at the American College of Rheumatology annual meeting shed new light on the connection between rheumatoid arthritis and heart disease and the factors that seem to put some rheumatoid arthritis patients in greater jeopardy of heart problems.
A fine-grained scan of DNA in lung cancer cells has revealed a gene fusion– a forced merger of two normally separate genes– that spurs the cells to divide rapidly, scientists report.
Borrowing a tactic used to identify lung infections, researchers have discovered a potential method to identify traumatic brain injuries that uses positron emission tomography scans and the body’s immune response to a brain injury.
Dendrites, the branch-like projections of neurons, were once thought to be passive wiring in the brain. But now, researchers have shown that these dendrites do more than relay information from one neuron to the next.
The largest international Alzheimer's disease genetics collaboration to date has found 11 new genetic areas of interest that contribute to late onset Alzheimer's Disease (LOAD).
Hunting for compounds that target the cancer stem cells of the blood cancer acute myeloid leukemia (AML) is now easier thanks to work by a team of scientists who built a new cell culture model that mimics AML in its niche in the bone marrow and makes the search for promising new drugs more effective.
Mice models of Alzheimer's treated with one abdominal injection of an antibody fragment designed by researchers showed, after only five days, improved memory and ability to learn as the result of less aggregated toxins and an increase in the number of neurons.
The considerable diversity of HIV worldwide represents a critical challenge for designing an effective HIV vaccine. Now, a scientific team has shown that bioinformatically optimized HIV vaccine antigens might be useful in the design of a global HIV vaccine.
According to a new study, a novel mammography procedure could generate substantial added-value for the diagnosis of breast cancer in medical practice.
A novel combination of two oral targeted drugs dramatically slowed the growth of glioblastoma brain tumors in mice and significantly extended the animals’ survival, scientists report.
Stroke is caused by a blood clot blocking a blood vessel in the brain, which leads to interruption of blood flow and shortage of oxygen. Now, a research group has taken an important step towards a treatment for stroke using stem cells.
In the fight to cure human immunodeficiency virus (HIV), researchers have been dealt a blow. A new study shows that the pool of inactive HIV viruses that lingers silently in a patient’s body is larger than expected.
Researchers have published the most comprehensive review of the benefits and risks of a daily dose of prophylactic aspirin and warn that greater understanding of side effects is needed.
Researchers have discovered a novel genetic cause of severe obesity which, although relatively rare, demonstrates for the first time that genes can reduce basal metabolic rate.
A new breast cancer risk gene has been discovered which explains the early-onset breast cancer in some multiple-case breast cancer families.
Cancer researchers have deciphered the operating principles of a genetic switch that cancer cells use to decide when to metastasize and invade other parts of the body.
Doctors now have convincing evidence that they put HIV into remission, hopefully for good, in a Mississippi baby born with the AIDS virus— a medical first that is prompting a new look at how hard and fast such cases should be treated.
In a small preliminary study, researchers say a blood test based on detection of epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always fatal because of its late diagnosis.
Veterinary researchers have helped identify the origin and possible evolution of an emerging swine virus with high mortality rates that has already spread to at least 17 states. They have traced the recent U.S. outbreaks to a strain from the Anhui province in China.
History’s largest schizophrenia study has confirmed several predictions about the disorder. One is the notion that calcium signaling pathways—and thus, existing drugs for other disorders, like popular calcium channel blockers—may play a key future role. Another is the notion that thousands of common gene variants—not a handful of rare ones—are major culprits.
Studying spinal fluid from people at risk for Alzheimer’s disease, researchers have found that a gene variation that had not been considered risky actually can increase the chances of developing Alzheimer’s disease when it occurs in tandem with another gene variant known to elevate risk.
New research shows that one of the brain’s fundamental self-protection mechanisms depends on coordinated, finely calibrated teamwork among neurons and non-neural cells knows as glial cells, which until recently were thought to be mere support cells.