Patients with severe ischemic heart disease and heart failure can benefit from a new treatment in which stem cells found in bone marrow are injected directly into the heart muscle, according to research presented at the American College of Cardiology's 63rd Annual Scientific Session.
It doesn’t take long for the flu virus to outsmart Tamiflu. EPFL scientists have developed a tool that reveals the mutations that make the virus resistant, and they have identified new mutations that may render ineffective one of the few treatments currently available on the market.
In the context of learning and memory, the primary visual cortex is the Rodney Dangerfield of cortical areas: It gets no respect. Also known as “V1,” this brain region is the very first place where information from the retina arrives in the cerebral cortex.
New guidelines that ease the recommended blood pressure could result in 5.8 million U.S. adults no longer needing hypertension medication. The findings are the first peer-reviewed analysis to quantify the impact of guidelines announced in February by the Eighth Joint National Committee. In a divisive move, the committee relaxed the blood pressure goal in adults 60 years and older to 150/90, instead of the previous goal of 140/90.
Combating the tissue degrading enzymes that cause lasting damage following a heart attack is tricky. Each patient responds to a heart attack differently and damage can vary from one part of the heart muscle to another, but existing treatments can’t be fine-tuned to deal with this variation. Penn researchers have developed a way to address this problem via a material that can be applied directly to the damaged heart tissue.
Analysis of surveys of more than 3.5 million American men and women, administered at some 20,000 health centers across the country—believed to be the largest analysis of its kind ever performed—found that married people, regardless of age, sex, or even cardiovascular risk factors, had significantly less chances of having any kind of cardiovascular disease than those who were single, divorced or widowed.
A new understanding of proteins at the nexus of a cell’s decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics (CTBP). Experiments and computer analysis of two key proteins revealed a previously unknown binding interface that could be addressed by medication.
In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the impact of chronic, early-life stress upon behavior—both at the time that stress is experienced, and upon the same individuals later in life, during adulthood.
There's fresh evidence that a lot of young people could be headed for heart trouble. A large study of preteens in Texas found that about one-third of them had borderline or high cholesterol when tested during routine physical exams. The results seem to support recent guidelines that call for every child to have a cholesterol test between 9 and 11.
The government's estimate of autism has moved up again to 1 in 68 U.S. children, a 30 percent increase in two years. But health officials say the new number may not mean autism is more common. Much of the increase is believed to be from a cultural and medical shift, with doctors diagnosing autism more frequently.
George Washington University researcher Narine Sarvazyan, PhD, has invented a new organ to help return blood flow from veins lacking functional valves. A rhythmically contracting cuff made of cardiac muscle cells surrounds the vein acting as a 'mini heart' to aid blood flow through venous segments. The cuff can be made of a patient’s own adult stem cells, eliminating the chance of implant rejection.
Scientists at Plant & Food Research, working together with researchers at The University of Auckland and the National Cancer Institute of The Netherlands, have discovered specific plant compounds able to inhibit transport mechanisms in the body that select what compounds are absorbed into the body,and eventually into cells. These same transport mechanisms are known to interfere with cancer chemotherapy treatment.
Neuroscientists report they have identified what they believe is the cause of the vast disintegration of a part of the brain called the corpus striatum in rodents and people with Huntington’s disease: loss of the ability to make the amino acid cysteine.
In a series of studies researchers have used specialized 3-D MRI scans to precisely measure living and dying tumor tissue to quickly show whether highly toxic chemotherapy is working.
A team of researchers believe their findings could have important implications for the way that rheumatoid arthritis is diagnosed and treated. They say that more accurate clinical testing is now needed to better identify rheumatoid arthritis and to prevent it being misdiagnosed.
The formula for peak exercise heart rate that doctors have used for decades in tests to diagnose heart conditions may be flawed because it does not account for differences between men and women, new research says.
Cholesterol levels fluctuate based on the time of year with more unfavorable lipid profiles seen in the colder months, a trend that may be driven by related behavior changes, according to new research.
A small study that examined brains from children who died found abnormal patterns of cell growth in autistic children. The research bolsters evidence that something before birth might cause autism, at least in some cases.
Research published online in Blood presents an unprecedented look at five unique blood cells in the human body, pinpointing the location of key genetic regulators in these cells and providing a new tool that may help scientists to identify how blood cells form and shed light on the etiology of blood diseases.
Just as archeologists try to decipher ancient tablets to discern their meaning, UT Southwestern Medical Center cancer biologists are working to decode the purpose of an ancient gene considered one of the most important in cancer research. The p53 gene appears to be involved in signaling other cells instrumental in stopping tumor development. But the p53 gene predates cancer, so scientists are uncertain what its original function is.
The problems people with autism have with memory formation, higher-level thinking and social interactions may be partially attributable to the activity of receptors inside brain cells, researchers at Washington University School of Medicine in St. Louis have learned.
A mathematical model created by Penn State researchers can predict with more than 90 percent accuracy the blood glucose levels of individuals with type 1 diabetes up to 30 minutes in advance of imminent changes in their levels—plenty of time to take preventative action.
Lab tests at Texas A&M AgriLife Research have shown that treatments with peach extract inhibit breast cancer metastasis in mice. AgriLife Research scientists say that the mixture of phenolic compounds present in the peach extract are responsible for the inhibition of metastasis, according to the study.
A team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Partha Mitra describes a new mathematical model that combines large data sets to predict where different types of cells are located within the brain, based on their molecular identity.
For the millions of people forced to rely on a plastic tube to eliminate their urine, developing an infection is nearly a 100 percent guarantee after just four weeks. But with the help of a little bubble-blowing, biomedical engineers hope to bring relief to urethras everywhere.