Princeton University officials decided Monday to make available a meningitis vaccine that hasn't been approved in the U.S. to stop the spread of the sometimes deadly disease on campus.
Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings reveal how a protein, called ‘PRH’, is normally able to prevent cells from unnecessary migration. It is likely that this protein is less effective in cancer cells allowing the cells to venture away.
In spite of the fact that the first antibiotics were discovered almost a century ago, infectious diseases such as tuberculosis, encephalitis and meningitis are still serious diseases for humans. The World Health Organization (WHO) estimates that there are more than 8 million new cases of tuberculosis per year on a global scale, and that more than 300,000 of these are due to multidrug-resistant strains that are difficult to treat.
The layers of skin that form the first line of defense in the body’s fight against infection have revealed a unanticipated secret. The single cell type that was thought to be behind the skin’s immune defense has been found to have a doppelganger, with researchers from the Walter and Eliza Hall Institute showing the cells, despite appearing identical, are actually two different types.
Scientists have found that the immune system’s behavior can act as an early warning alarm that detects cancer recurrence, and this could offer a chance for pre-emptive treatment before the disease takes hold for the second time. The study, in mice, involved researchers looking for early signs of the immune response ‘kicking in’ indicating that the cancer was once more awake.
A new method to take the DNA fingerprint of individual cancer cells is uncovering the true extent of cancer’s genetic diversity, new research reveals. The technique can identify the founding mutations from which a tumor evolved and then uses computer software to draw a map of the cancer’s family tree.
Mutations in the genes that defend the body against cancer-related viruses and other infections may play a larger role in breast cancer than previously thought. A researcher looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them. The mutations were each different, but all would have affected some aspect of pathogen recognition and defense.
Investigators have used a new sequencing method to identify a group of genes used by the brain's immune cells– called microglia– to sense pathogenic organisms, toxins or damaged cells that require their response.
Researchers have developed a new technique for fighting deadly and hard-to-treat pancreatic cancer that uses two different types of nanoparticles, the first type clearing a path into tumor cells for the second, which delivers chemotherapy drugs.
The U.S. Food and Drug Administration today approved a device to help reduce the frequency of seizures in epilepsy patients who have not responded well to medications.
A way of using nanoparticles to investigate the mechanisms underlying "mystery" cases of infertility has been developed by scientists.
Washington University School of Medicine in St. Louis now offers genetic testing to help diagnose and treat patients with heart disorders that can lead to sudden death.
The transplant anti-rejection drug rapamycin showed unexpected benefits in a mouse model of a fatal defect in the energy powerhouses of cells, the mitochondria.
For the worst cases of type 1 diabetes, islet transplantation already has freed hundreds of people from complete dependence on insulin and from life-threatening consequences of the disease. However, the procedure still is regarded as experimental by the U.S. Food and Drug Administration (FDA).
Enhanced extracts made from special antioxidants in spearmint and rosemary improve learning and memory, a study in an animal model has found.
Tiny amounts of a specific type of lipid in the small intestine may play a greater role than previously thought in contributing to clogged arteries. Researchers were able to reduce the negative effects of these lipids in mice by feeding them a genetically engineered tomato, designed to mimic HDL ("good") cholesterol.
Friendly microbes in the intestinal tracts (guts) of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists.
A new study suggests that many infants dying suddenly and unexpectedly in all kinds of sleep environments have underlying brainstem abnormalities.
A strain of bird flu that scientists thought could not infect people has shown up in a Taiwanese woman, a nasty surprise that shows scientists must do more to spot worrisome flu strains before they ignite a global outbreak, doctors say.
Using scores obtained from cognitive tests, researchers think they have developed a model that could help determine whether memory loss in older adults is benign or a stop on the way to Alzheimer’s disease.
Researchers have taken a step forward in unravelling the causes of a commonly inherited intellectual disability, finding that a genetic mutation leads to a reduction in certain proteins in the brain.
Scientists have used stem cells created from the skin of patients with a rare form of diabetes to elucidate an important biochemical pathway for beta-cell failure in diabetes.
To better understand and one day provide improved treatments for depression, addiction and anxiety, researchers are using tiny, electronic devices to identify and map neural circuits in the brain.
A UCLA doctor recently enrolled a patient in a Phase 3 trial that uses a patient's own blood-derived stem cells to try to restore circulation to the heart.