A large-scale University-led study involving more than 180,000 people shows that patients treated with a drug widely prescribed for type 2 diabetes can live longer than people without the condition. The findings indicate that a drug known as metformin, used to control glucose levels in the body and already known to exhibit anticancer properties, could offer prognostic and prophylactic benefits to people without diabetes.
A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment.
Cognitive abilities such as memory and attention are not only important after a stroke but also before. Previous studies have shown poor cardiovascular health can increase the risk of cognitive impairment such as problems in memory and learning. However, the opposite idea that cognitive impairment may impact cardiovascular health, specifically stroke, was not established before.
The World Health Organization on Friday declared the Ebola outbreak in West Africa to be an international public health emergency that requires an extraordinary response to stop its spread. The WHO announced the Ebola outbreak — the largest and longest in history — is worrying enough to merit being declared an international health emergency. WHO declared similar emergencies for the swine flu pandemic in 2009 and for polio in May.
Cancer cells that break away from tumors to go looking for a new home may prefer to settle into a soft bed. Some particularly enterprising cancer cells can cause a cancer to spread to other organs, called metastasis, or evade treatment to resurface after a patient is thought to be in remission. A team found that these so-called tumor-repopulating cells may lurk quietly in stiffer cellular environments, but thrive in a softer space.
Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumor genetic analysis ever conducted, revealing a new approach to classifying cancers. The work not only revamps traditional ideas of how cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug development.
At least one part of the human brain may be able to process information the same way in older age as it does in the prime of life, according to new research conducted at the University of Adelaide. A study compared the ability of 60 older and younger people to respond to visual and non-visual stimuli in order to measure their "spatial attention" skills.
A nasal brush test can rapidly and accurately diagnose Creutzfeldt-Jakob disease (CJD), an incurable and ultimately fatal neurodegenerative disorder, according to a new study.
In the largest study of its kind, researchers suggests that in older people, not getting enough vitamin D may double the risk of developing dementia and Alzheimer’s disease.
Thinking about getting inked? Check the bottle first. The Food and Drug Administration is warning tattoo parlors, their customers and those buying at-home tattoo kits that not all tattoo ink is safe.
It's long been known that faulty BRCA genes greatly raise the risk for breast cancer. Now, scientists say a more recently identified, less common gene - called PALB2 - can do the same.
In this episode of Bioscience Technology This Week, News Editor Christina Jakubowski highlights the role of the protein GSK-3 in brain development and also reports that running, regardless of duration or speed, reduces death risk.
Scientists report they can crank up insect aggression simply by interfering with a basic metabolic pathway in the insect brain. Their study, of fruit flies and honey bees, shows a direct, causal link between brain metabolism (how the brain generates the energy it needs to function) and aggression.
Frogs, dogs, whales, snails can all do it, but humans and primates can't. Regrow nerves after an injury, that is— while many animals have this ability, humans don't. But now, new research suggests that a small molecule may be able to convince damaged nerves to grow and effectively rewire circuits.
The relationship between saturated fat and type 2 diabetes may be more complex than previously thought, according a study that claims saturated fatty acids can be associated with both an increased and decreased risk of developing the disease, depending on the type of fatty acids present in the blood.
A team of scientists has developed an entirely non-invasive technique that provides a view of blood flow in the brain. The tool could provide powerful insights into strokes and possibly Alzheimer's disease.
There is good news in attempts to halt HIV by growing, in patients, new immune systems lacking a gene that led to the first—and only—cured HIV patient. Using hematopoietic (blood) stem cells possessing a CCR5 gene mutation that blocks CD4 T cell entry of HIV, Calimmune—led by Nobel Laureate David Baltimore—has, for one year, safely begun growing new immune systems in patients.
Eating baked or broiled fish once a week is good for the brain, regardless of how much omega-3 fatty acid it contains, according to researchers at the University of Pittsburgh School of Medicine. The findings add to growing evidence that lifestyle factors contribute to brain health later in life.
Effective new drugs and screening would make hepatitis C a rare disease by 2036, according to a computer simulation conducted by The University of Texas MD Anderson Cancer Center and the University of Pittsburgh Graduate School of Public Health.
Researchers have achieved a technical breakthrough that should result in speedier diagnosis of cancer and various pre-natal conditions. The key discovery lies in a new tool that allows researchers to load long strands of DNA into a tunable nanoscale imaging chamber in ways that maintain their structural identity and under conditions that are similar to those found in the human body.
University of Michigan Health System researchers revealed an obesity paradox among older Americans suffering from sepsis. In a study of 1,404 Medicare beneficiaries, heavier patients were more likely to survive the life-threatening infection that can lead to a stay in a hospital’s intensive care unit.
The body’s assailants are cleverer than previously thought. New research from Lund University in Sweden shows for the first time how bacteria in the airways can help each other replenish vital iron. The bacteria thereby increase their chances of survival, which can happen at the expense of the person’s health.
The tiny addition of a chemical mark atop a gene that is well known for its involvement in clinical depression and posttraumatic stress disorder can affect the way a person’s brain responds to threats, according to a new study.
A large DNA analysis of people with and without pancreatic cancer has identified several new genetic markers that signal increased risk of developing the highly lethal disease, scientists report.
Researchers report that dietary capsaicin– the active ingredient in chili peppers– produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors.