A type of cell that builds mouse hearts can renew itself, researchers report. They say the discovery, which likely applies to such cells in humans as well, may pave the way to using them to repair hearts damaged by disease— or even grow new heart tissue for transplantation.
Researchers have discovered that stem cells taken from teeth can grow to resemble brain cells, suggesting they could one day be used in the brain as a therapy for stroke.
Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors to hereditary cancer risk in the human population. Now, investigators are reporting a new mechanism by which BRCA gene loss may accelerate cancer-promoting chromosome rearrangements.
Researchers found that the protein DAZAP1 plays a key role in the regulation of many genes through a process known as alternative splicing, and when highly expressed in cancer cell line experiments, DAZAP1 was shown to inhibit several types of cancer cells from dividing and moving.
Scientists from the University of Manchester have discovered that microbes in smaller groups are more likely to mutate, resulting in higher rates of antibiotic resistance. The more ‘lonely’ bacteria mutated more, and developed greater resistance to the well-known antibiotic Rifampicin, used to treat tuberculosis.
A multinational team of scientists presents new evidence supporting the theory that in at least some cases of schizophrenia, autism and intellectual disability (ID), malfunctions in some of the same genes are contributing to pathology.
There is new, more definitive evidence implicating camels in the ongoing outbreak of Middle East Respiratory Syndrome, or MERS. Scientists extracted a complete, live, infectious sample of MERS coronavirus (MERS-CoV) from two camels in Saudi Arabia.
Type 2 diabetes may be associated with brain degeneration, according to a new multicenter study. The study also found that, contrary to common clinical belief, diabetes may not be directly associated with small vessel ischemic disease.
Scientists have identified one of the molecular pathways that resveratrol, the component of grapes and red wine associated with health benefits, uses to achieve its beneficial action.
National Institutes of Health (NIH) researchers have developed an animal model of human hantavirus pulmonary syndrome (HPS) in rhesus macaques, an advance that may lead to treatments, vaccines and improved methods of diagnosing the disease.
Experimental studies have shown that deep brain stimulation (DBS) within the subcallosal cingulate (SCC) white matter of the brain is an effective treatment for many patients with treatment-resistant depression. Response rates are between 41 percent and 64 percent across published studies to date. One of the proposed mechanisms of action is through modulation of a network of brain regions connected to the SCC.
The gene mutation that causes Huntington’s disease appears in every cell in the body, yet kills only two types of brain cells. Why? Scientists used a unique approach to switch the gene off in individual brain regions and zero in on those that play a role in causing the disease in mice.
Dangerous overnight blood sugar levels often go undetected and cause prolonged periods of heart rhythm disturbances in older patients with Type 2 diabetes and associated heart problems, new research reveals. The findings could offer clues to the mechanism by which low blood sugar levels could contribute to life-threatening changes in heart rhythm.
Scientists studying cancerous tumor tissues in a laboratory believe they have identified a potential new strategy to treat ovarian cancer by targeting ovarian tumor growth through the inhibition of the development of new tumor blood vessels.
For many people, fear of flying or of spiders is more than just a momentary increase in heart rate and a pair of sweaty palms, it’s a hard-core phobia. Now, a team of researchers may have found a way to silence the gene that feeds this fear.
Scientists have developed a new circuit board- dubbed the Neurogrid, consisting of 16 custom-designed "Neurocore" chips- modeled on the human brain, possibly opening up new frontiers in robotics and computing.
A study tracing the evolution of HIV in North America has found evidence that the virus is slowly adapting over time to its human hosts. However, this change is so gradual that it is unlikely to have an impact on vaccine design.
Scientists have known that abnormal brain growth is associated with autism spectrum disorder. However, the relationship between the two has not been well understood. Now, scientists have shown that mutations in a specific gene that is disrupted in some individuals with autism results in too much growth throughout the brain.
Researchers have found a circuit in the brain of fruit flies that controls their daily, rhythmic behavior of rest and activity. The new study also found that the fly version of the human brain protein known as corticotrophin releasing factor is a major coordinating molecule in this circuit.
Large sections of the genome that were once referred to as “junk” DNA have been linked to human heart failure, according to new research. So-called junk DNA was long thought to have no important role in heredity or disease because it doesn’t code for proteins.
Using a mixture of cervical cancer cells and a hydrogel substance that resembles an ointment balm, an engineer has devised a method for 3-D printing tumors that could soon be taking cancer research out of the petri dish.
Ten years of U.S. data suggest that calorie and fat intake increased among statin users during the decade, an indication that many patients might be abandoning heart-healthy lifestyles and assuming that drugs alone will do the trick, the study authors said.
Federal health regulators have cleared a genetic test from Roche as a first-choice screening option for cervical cancer. It was a role previously reserved for the Pap smear, the decades-old mainstay of women's health.
520 million years ago, the first known animal heart, the heart of an ancient shrimp, was formed. Now, it, and its vascular system, have been found to be more complex than that of modern shrimp, researchers report.
Fibroblasts could offer an alternative to heart transplants for patients with heart disease. Researchers found that the heart cell fibroblast is a close relative to a cardiomyocyte, the cell responsible for a healthy beating heart.