A handheld diagnostic device that MGH investigators first developed to diagnose cancer has been adapted to rapidly diagnose tuberculosis and other important infectious bacteria. New research describes portable devices that combine microfluidic technology with nuclear magnetic resonance (NMR) to not only diagnose these important infections, but also determine the presence of antibiotic-resistant bacterial strains.
Because physiological evidence confirming schizophrenia can only be gathered from the brain during an autopsy, mental health professionals have had to rely on a battery of psychological evaluations to diagnose their patients. Now, researchers have discovered a method for physical diagnosis— by collecting tissue from the nose through a simple biopsy.
By using swarms of untethered grippers, each as small as a speck of dust, engineers and physicians say they have devised a new way to perform biopsies that could provide a more effective way to access narrow conduits in the body as well as find early signs of cancer or other diseases.
Scientists have developed a new technique that could be used in blood tests to detect a range of age-related conditions such as diabetes, dementia and Alzheimer’s.
Engineers have developed a portable device to count white blood cells that needs less than a pinprick's worth of blood and takes just minutes to run.
The first multi-gene test that can help predict cancer patients' responses to treatment using the latest DNA sequencing techniques has been launched in the NHS. The test detects mutations across 46 genes in cancer cells.
Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present. Now, a team of researchers has devised a molecular sensor that can detect levels of lactate in individual cells in real time.
A new immunoassay that tests for the presence of three biomarkers appears to be a valid screening method for the early detection of malignant kidney cancer, according to new data.
Diagnostics maker Cepheid said Tuesday it will work with Oregon Health & Science University to develop tests that predict the risk of recurrence of breast and prostate cancer. Cepheid said it will work with OHSU's Knight Cancer Institute. The tests will run on the Cepheid GeneXpert system....
Researchers “cured” a strain of bacteria of its ability to resist an antibiotic in an experiment that has implications for a long-standing public health crisis.
Researchers have released an improved version of an online decision-support tool that has helped health-care providers adopt universal standards to identify materials, locations and partners within the U.S. health-care system.
A team of researchers has identified a protein with broad virus-fighting properties that potentially could be used as a weapon against deadly human pathogenic viruses such as HIV, Ebola, Rift Valley Fever, Nipah and others.
Young adults are often reluctant to seek treatment for mental health problems because of the stigma, inadequate insurance coverage and difficulty finding a mental health care provider, but a new study by suggests that depression symptoms may be significantly reduced when patients interact with computerized avatars— virtual 3D images of a healthcare provider like a nurse practitioner or physician— to rehearse office visits ahead of time and learn self-management skills.
Halting the March of Rheumatoid Arthritis
Having blood drawn and analyzed to diagnose disease is a process that can take a few days, but what if your doctor could perform this analysis in moments, right before your eyes? That’s the promise of “lab on a chip” technology, and researchers are working on a variety of fronts to remove technical roadblocks.
Bio-Rad Laboratories, Inc. and the American Red Cross announced that the U.S. Food and Drug Administration (FDA) has notified Bio-Rad that it may proceed with its Investigational New Drug (IND) study for the Bio-Rad Dengue NS1 Ag microplate assay
BD (Becton, Dickinson and Company) and the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) through the U.S. Department of Health and Human Services’ Centers for Disease Control and Prevention (CDC) set in motion a joint, multi-year initiative to improve blood collection practices in African clinics and hospitals.
One of the overarching trends for Life Sciences has been the need for biocompatible materials and processes. For analytical and diagnostic systems, the word biocompatibility refers to the interaction between any component in the system and the biological sample
Turning glass slides into digital slides creates new analysis options.
A flexible, high-throughput DNA methylation profiling technology has been introduced that is capable of surveying up to 1,536 methylation sites across 96 samples simultaneously. Illumina Inc.
Proteomics, the successor to genomics, has rapidly assumed a central role in modern biology and medicine. Where the human genome contains about 22,000 coding genes, the functional proteome is comprised of anywhere from fifteen to a hundred times as many proteins.
The DSX workstation finds use in a number of applications clinical diagnostics, assay design, ADME tox and drug discovery in any laboratory performing ELISA assays.
The DSX workstation finds use in a number of applications clinical diagnostics, assay design, ADMEtox and drug discovery in any laboratory performing ELISA assays.
Future strategies for detection and treatment