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The Lead

10 Up-and-Coming Healthcare Medical Innovations

December 17, 2014 5:32 pm | by Christina Jakubowski, Managing Editor | Articles | Comments

The Cleveland Clinic recently unveiled their annual Top 10 Medical Innovations for 2015– a list that casts an optimistic light on up-and-coming healthcare advances that may reach consumers next year.                                       

Stem Cells Faulty in Duchenne Muscular Dystrophy

December 17, 2014 4:03 pm | by Stanford University | News | Comments

Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive muscle...

Novel Tool to Study Life-Threatening Arrhythmias: A Genetically Engineered Pig

December 17, 2014 10:18 am | by NYU Langone | News | Comments

Researchers at NYU Langone Medical Center have developed the first large animal model of an...

Blow to Chest Could Trigger Potentially Dangerous Heart Rhythm

December 15, 2014 11:39 am | News | Comments

A hard hit to the chest can cause an irregular heartbeat that may lead to death even days after...

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Smoking Linked to Loss of Y Chromosome in Men

December 5, 2014 12:32 pm | News | Comments

In a new study, researchers demonstrated an association between smoking and loss of the Y chromosome in blood cells. The researchers have previously shown that loss of the Y chromosome is linked to cancer.          

Mediterranean Diet Has Marked Impact on Aging

December 3, 2014 3:42 pm | by Brigham and Women’s Hospital | News | Comments

The  Mediterranean diet consistently has been linked with an array of health benefits, including decreased risk of chronic disease and cancer. Until now, however, no studies had associated the diet with longer telomeres, one of the biomarkers of aging. Read more...

Another Case Against the Midnight Snack

December 3, 2014 10:49 am | News | Comments

These days, with the abundance of artificial light, TV, tablets and smartphones, adults and children alike are burning the midnight oil. What they are not burning is calories: with later bedtimes comes the tendency to eat. Read more...                                 

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Traffic Jams Can Hurt the Heart

December 2, 2014 11:58 am | News | Comments

Anyone who has experienced Los Angeles gridlock likely can attest that traffic may cause one's blood pressure to rise. But researchers have found that, beyond the aggravation caused by fellow drivers, traffic-related air pollution presents serious heart health risks.

Tiny Patient Prompts Advance in Neurogenetics

November 24, 2014 11:54 am | News | Comments

Researchers had never shown exactly how cells in the brain stem detect carbon dioxide and regulate breathing in humans. After taking a mutation from a two-month-old baby and expressing it in human astrocytes, they did exactly that, and the research may lead to an early warning system to save premature infants.

Cellular Origin of Fibrosis

November 21, 2014 10:00 am | News | Comments

Harvard Stem Cell Institute scientists at Brigham and Women’s Hospital say they have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions. Read more...

Study: Obesity Fuels Silent Heart Damage

November 21, 2014 9:27 am | News | Comments

Using an ultrasensitive blood test to detect the presence of a protein that heralds heart muscle injury, researchers from Johns Hopkins and elsewhere have found that obese people without overt heart disease experience silent cardiac damage that fuels their risk for heart failure down the road. Read more...      

3-D-Printed Model Helps Treat Patients with Heart Disorders

November 20, 2014 10:43 am | News | Comments

An experimental 3-dimensional printed model of the heart may help surgeons treat patients born with complicated heart disorders, according to new research.                           

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Early Statin Use May Give Long-term Heart Benefits

November 19, 2014 2:57 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

Research shows that taking a cholesterol-lowering drug for five years in middle age can lower heart and death risks for decades afterward. The benefits seem to grow over time and may last for life.               

Mental Health Problems Increase Cardiovascular Disease Risk

November 19, 2014 2:18 pm | by Cynthia Fox, Science Writer | Articles | Comments

People with mental health problems are “significantly” more likely to have stroke or heart disease, according to a study unveiled at a recent Canadian Cardiovascular Congress.                    

Statins Reverse Learning Disabilities Caused by Genetic Disorder

November 17, 2014 11:05 am | News | Comments

UCLA scientists have discovered that statins, a popular class of cholesterol drugs, reverse the learning disabilities caused by a genetic disorder called Noonan syndrome. Read more..                            

Calculator Adds Up Cardio Risks

November 17, 2014 10:28 am | News | Comments

The new Healthy Heart Score developed by researchers at the Harvard T.H. Chan School of Public Health (HSPH) gives individuals an easy way to estimate their 20-year risk of developing cardiovascular disease (CVD) based on simple lifestyle habits. Read more...

Imaging Method Could Improve Asthma Treatment

November 14, 2014 12:21 pm | News | Comments

A team of researchers have used a laser beam trap to examine how drug particles from asthma inhalers behave as they are projected through the air. Their findings could improve the effectiveness of inhalers for the over five million people in the UK suffering from asthma.

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Gene Study Boosts Interest in Heart Drug

November 12, 2014 5:57 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

Scientists have discovered gene mutations that give people naturally lower cholesterol levels and cut their risk of heart disease in half. That discovery may have a big implication for a blockbuster heart drug.           

Getting to the Heart of the Heart

November 6, 2014 2:13 pm | News | Comments

For years, a multidisciplinary research team has tracked an elusive creature, a complex of proteins thought to be at fault in some cases of sudden cardiac death. Now, they have finally captured images of the complex.          

Fruit Chemicals May Minimize Organ Damage After Heart Attack, Stroke

November 6, 2014 1:58 pm | News | Comments

Scientists have identified chemicals found in some everyday fruit that could protect vital organs from long-term damage following a heart attack or stroke, according to new research.                    

Genetic Damage Caused by Asthma Shows Up in Blood Stream

November 5, 2014 12:52 pm | News | Comments

Asthma may be more harmful than was previously thought, according to researchers who found that genetic damage is present in circulating, or peripheral, blood.                          

Novel Ultrasound Technology Screens for Heart Conditions

October 30, 2014 1:41 pm | News | Comments

Engineers have determined for the first time the impact of a ring-shaped vortex on transporting blood flow in normal and abnormal ventricles within the human heart. In order to make the study possible, researchers have developed a novel ultrasound technology that makes screening cheaper and much easier.

World-First Embryonic Stem Cell Trial for the Heart

October 30, 2014 9:37 am | by Cynthia Fox, Science Writer | Articles | Comments

The first embryonic stem (ES) cell trial for severe heart failure is launching now in Paris. The long-awaited trial comes after much preclinical cell work on more than 350 rats, 50 immunodeficient mice and 32 non-human primates.       

DNA-repairing Enzyme Can Worsen Tissue Damage

October 28, 2014 3:04 pm | News | Comments

When tissues are deprived of blood, as happens during a stroke or heart attack, the lack of oxygen can cause serious damage. A new study shows that surprisingly, a DNA-repair enzyme called Aag actually makes this damage worse.       

Vitamin D Deficiency Ups Attack Risk in Asthmatics

October 28, 2014 2:03 pm | News | Comments

A new study points to a convenient, free way to manage acute asthmatic episodes— catching some rays outside. The research showed that asthmatics with vitamin D deficiency were 25 percent more likely to experience acute attacks.       

Babies’ Hearts May Beat Path to Heart Attack Treatments

October 17, 2014 11:50 am | Videos | Comments

The seemingly miraculous power of babies’ hearts to repair themselves after being injured has spurred a research team to investigate if this ability can be harnessed for new heart attack treatments.               

Repair Process Suggests Potential Heart Attack Treatment Strategy

October 16, 2014 2:47 pm | News | Comments

Researchers have discovered that some scar-forming cells in the heart, known as fibroblasts, have the ability to become endothelial cells— the cells that form blood vessels. The finding could point the way toward a new strategy for treating people who have suffered a heart attack

Weight Gain Study Suggests Polyunsaturated Oil Healthier Option

October 16, 2014 2:33 pm | News | Comments

Short-term modest weight gains in healthy, normal weight young adults was associated with more bad cholesterol levels in those who ate muffins cooked using saturated oil. However, individuals in the same study who ate muffins made with polyunsaturated oils had improved blood cholesterol profiles, according to a new study. 

Explaining More About Airway Closure During Asthma Attacks

October 16, 2014 2:28 pm | News | Comments

In acute asthma, various triggers, including viral illnesses and aeroallergens, can cause acute narrowing of the airways leading to a life-threatening respiratory crisis and sometimes death. Researchers have identified a novel factor that puts the brakes on airway smooth-muscle contraction relevant to asthma.

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