New guidelines that ease the recommended blood pressure could result in 5.8 million U.S. adults no longer needing hypertension medication. The findings are the first peer-reviewed analysis to quantify the impact of guidelines announced in February by the Eighth Joint National Committee. In a divisive move, the committee relaxed the blood pressure goal in adults 60 years and older to 150/90, instead of the previous goal of 140/90.
Combating the tissue degrading enzymes that cause lasting damage following a heart attack is tricky. Each patient responds to a heart attack differently and damage can vary from one part of the heart muscle to another, but existing treatments can’t be fine-tuned to deal with this variation. Penn researchers have developed a way to address this problem via a material that can be applied directly to the damaged heart tissue.
Analysis of surveys of more than 3.5 million American men and women, administered at some 20,000 health centers across the country—believed to be the largest analysis of its kind ever performed—found that married people, regardless of age, sex, or even cardiovascular risk factors, had significantly less chances of having any kind of cardiovascular disease than those who were single, divorced or widowed.
There's fresh evidence that a lot of young people could be headed for heart trouble. A large study of preteens in Texas found that about one-third of them had borderline or high cholesterol when tested during routine physical exams. The results seem to support recent guidelines that call for every child to have a cholesterol test between 9 and 11.
George Washington University researcher Narine Sarvazyan, PhD, has invented a new organ to help return blood flow from veins lacking functional valves. A rhythmically contracting cuff made of cardiac muscle cells surrounds the vein acting as a 'mini heart' to aid blood flow through venous segments. The cuff can be made of a patient’s own adult stem cells, eliminating the chance of implant rejection.
The formula for peak exercise heart rate that doctors have used for decades in tests to diagnose heart conditions may be flawed because it does not account for differences between men and women, new research says.
Cholesterol levels fluctuate based on the time of year with more unfavorable lipid profiles seen in the colder months, a trend that may be driven by related behavior changes, according to new research.
Research published online in Blood presents an unprecedented look at five unique blood cells in the human body, pinpointing the location of key genetic regulators in these cells and providing a new tool that may help scientists to identify how blood cells form and shed light on the etiology of blood diseases.
A new microfluidic method for evaluating drugs commonly used for preventing heart attacks has found that while aspirin can prevent dangerous blood clots in some at-risk patients, it may not be effective in all patients with narrowed arteries. The study, which involved 14 human subjects, used a device that simulated blood flowing through narrowed coronary arteries to assess effects of anti-clotting drugs.
Although genome-wide association studies have linked DNA variants in the gene SCN10A with increased risk for cardiac arrhythmia, efforts to determine the gene's direct influence on the heart's electrical activity have been unproductive. Now, scientists have discovered that these SCN10A variants regulate the function of a different gene, SCN5A, which appears to be the primary gene responsible for cardiac arrhythmia risk.
When a heart gets damaged, such as during a major heart attack, there’s no easy fix. But scientists working on a way to repair the vital organ have now engineered tissue that closely mimics natural heart muscle that beats, not only in a lab dish but also when implanted into animals.
UT Southwestern Medical Center cardiologists have defined a novel heart failure symptom in advanced heart failure patients: shortness of breath while bending over, such as when putting on shoes. The condition, which UT Southwestern cardiologists named “bendopnea,” is an easily detectable symptom that can help doctors diagnose excessive fluid retention in patients with heart failure.
The health benefits of eating dark chocolate have been extolled for centuries, but the exact reason has remained a mystery. Now, researchers are reporting that certain bacteria in the stomach gobble dark chocolate and ferment it into anti-inflammatory compounds that are good for the heart.
A new study raises questions about current guidelines which generally restrict the consumption of saturated fats and encourage consumption of polyunsaturated fats to prevent heart disease. Researchers analyzed existing cohort studies and randomized trials on coronary risk and fatty acid intake. They showed that current evidence does not support guidelines that restrict the consumption of saturated fats in order to prevent heart disease.
Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks- a finding that opens the door to new testing or treatment of high cholesterol and other lipid disorders.
Scientists are reporting that one compound from “third-hand smoke,” which forms when second-hand smoke reacts with indoor air, damages DNA and sticks to it in a way that could potentially cause cancer.
It won't be nearly as much fun as eating candy bars, but a big study is being launched to see if pills containing the nutrients in dark chocolate can help prevent heart attacks and strokes.
Heart attack and stroke are among the most serious threats to health. But novel research at UT Southwestern Medical Center has linked two major biological processes that occur at the onset of these traumatic events and, ultimately, can lead to protection for the heart.
NIH researchers have identified a biological pathway that contributes to the high rate of vein graft failure following bypass surgery. Using mouse models of bypass surgery, they showed that excess signaling via the Transforming Growth Factor Beta (TGF-Beta) family causes the inner walls of the vein become too thick, slowing down or sometimes even blocking the blood flow that the graft was intended to restore.
As long as inexpensive statins, which lower cholesterol, are readily available and patients don’t mind taking them, it doesn’t make sense to do a heart scan to measure how much plaque has built up in a patient’s coronary arteries before prescribing the pills, according to a new study.
Obese adolescents not getting enough sleep? A new study shows they could be increasing their risk for developing diabetes, heart disease and stroke. Lack of sleep and obesity have been associated with an increased risk of cardiovascular and metabolic diseases in adults and young children. However, the association is not as clear in adolescents.
In a study that began in a pair of infant siblings with a rare heart defect, Johns Hopkins researchers say they have identified a key molecular switch that regulates heart cell division and normally turns the process off around the time of birth. Their research, they report, could advance efforts to turn the process back on and regenerate heart tissue damaged by heart attacks or disease.
A team of researchers developed a material that could help prevent blood clots associated with catheters, heart valves, vascular grafts and other implanted biomedical devices. Blood clots at or near implanted devices are thought to occur when the flow of nitric oxide, a naturally occurring clot-preventing agent generated in the blood vessels, is cut off. When this occurs, the devices can fail.
In the heart, as in the movies, 3D action beats the 2D experience hands down. In 3D, healthy hearts do their own version of the twist. Rather than a simple pumping action, they circulate blood as if they were wringing a towel. The bottom of the heart twists as it contracts in a counterclockwise direction while the top twists clockwise. Scientists call this the left ventricular twist—and it can be used as an indicator of heart health.
Using a 3-D printer, biomedical engineers have developed a custom-fitted, implantable device with embedded sensors that could transform treatment and prediction of cardiac disorders. An international team of biomedical engineers and materials scientists have created a 3-D elastic membrane made of a soft, flexible, silicon material that is precisely shaped to match the heart’s epicardium, or the outer layer of the wall of the heart.