An abdominal aortic aneurysm- a bulge in the large artery that carries blood away from the heart- can be immediately life-threatening if it grows large enough to rupture. The chance of survival when it ruptures is less than 10 percent. Many people who find out they have that risk are able to have a minimally invasive repair. But up to 30 percent instead face a major open surgery with a long recovery because of the location of the aneurysm. Now, a new graft customized to their individual anatomy allows them, too, to have a quick recovery.
Researchers have found lovers’ hearts indeed beat for each other, or at least at the same rate in a series of studies on couples in romantic relationships.
Healthy men and women show little difference in their hearts, except for small electrocardiographic disparities. But new genetic differences found by Washington University in St. Louis researchers in hearts with disease could ultimately lead to personalized treatment of various heart ailments.
A new study could provide the link that scientists have been looking for to confirm that reactivation of a latent herpes virus is a cause of some heart problems. Looking at blood samples from 299 heart patients, researchers found that those who had suffered a heart attack were the most likely to have inflammatory proteins circulating in their blood compared to patients with less acute symptoms.
The risk of kidney failure is greater for people with chronic kidney disease who also have atrial fibrillation, one of the most common forms of irregular heart rhythm in adults, according to a new study. The finding opens the way for further studies into the relationship between the two factors, which could lead to new treatment approaches that would improve outcomes for people with chronic kidney disease.
A virtual heart, developed at The University of Manchester, is revealing new information about one of the world’s most common heart conditions. Researchers built an advanced computational model of an anatomically correct sheep’s heart. It was made by taking a series of very thin slices of the heart, imaging them in 2D, and then using a computer program to render them into a 3D model.
Scientists at the Texas Biomedical Research Institute have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery. These early results show promise for eventually developing stem cell therapies to restore human tissues or organs damaged by age or disease.
Researchers at Boston Children's Hospital have found, for the first time that young humans (infants, children and adolescents) are capable of generating new heart muscle cells. These findings refute the long-held belief that the human heart grows after birth exclusively by enlargement of existing cells.
Researchers have found a combination of biomarkers related to blood vessel and tissue injury that, when measured together, could signal when a transplanted heart is becoming damaged to the point of failure, a process that is often undetected. The markers would give doctors an opportunity to intervene and save a recipient's heart.
For more than half a century, researchers have known that the bacteria that colonize the gastrointestinal tract of mammals influence their host’s cholesterol metabolism. Now, scientists show that changes in cholesterol metabolism induced by diet can alter the gut flora.
Scientists have discovered a new gene mechanism that appears to regulate triglyceride levels. This pathway may protect carriers of a gene variant against cardiovascular disease, especially among those with greater intakes of polyunsaturated fat (PUFA).
A research team has decoded the entire pathway that regulates leakiness of blood vessels — a condition that promotes a wide number of disorders, such as heart disease, cancer growth and spread, inflammation and respiratory distress. They say their findings suggest that several agents already being tested for other conditions might reverse vessel leakiness.
Peptide Applications for Cardiovascular
This metabolic cart is useful for measuring breath-by-breath oxygen consumption and carbon dioxide production in exercising subjects.
The siLentMer siRNA search tool is available online at www.bio-rad.com/rnaisearch. It offers a way
The Pulsatile is ideal for many vascular procedures including angioplasty, disease models, or imaging studies. Blood flow can be adjusted by two means, allowing frequency and stroke volume to be altered.
The Blood Pump allows adjustment of blood flow by two means: the user can alter the frequency of the stroke and the volume of the stroke, which permits simulating either a normal or diseased heart. Pulsatile output closely simulates the ventricular action of the heart.
Clonetics Neonatal Rat Cardiac Myocytes are available for use in cardiovascular and toxicological research. These cryopreserved cells offer functional, beating cardiac myocytes upon thaw, at the user’s convenience.
These assays are central to kinase drug discovery programs for indications including oncology, inflammation, metabolic, cardiovascular and neurological diseases. The kits include Quansys Multiplexed ELISA (Quansys M.E.
Quansys Multiplexed ELISA Human Cytokine - IR (9-plex), Human Chemokine - IR (9-plex), Mouse
Millipore Corporation offers full-length mTOR kinase as part of their KinaseProfiler Service. The mTOR kinase has recently been linked to many important human diseases, including cancer, diabetes, obesity, cardiovascular disease ad neurological disorders.
LifeMarker protein assays quantify proteins from complex biological samples without the need for an antibody. The assays can be multiplexed to monitor a panel of protein markers.
Millipore Corp. has added the human L-type calcium channel, a voltage-gated channel involved in normal myocardial and vascular smooth muscle contractility, to its CardiacProfiler Service for compound liability testing.
This high throughput, colorimetric, competitive immunoassay, for the quantitative determination of cyclic AMP in tissue samples, uses a cAMP polyclonal antibody to bind, in a competitive manner, the cAMP in the standards or sample.