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Team Finds New Genetic Anomalies in Lung Cancer

December 22, 2014 10:56 am | News | Comments

Developing effective treatments for lung cancer has been challenging, in part because so many genetic mutations play a role in the disease. By analyzing the DNA and RNA of lung cancers, researchers at the University of Michigan Comprehensive Cancer Center found that patients whose tumors contained a large number of gene fusions had worse outcomes than patients with fewer gene fusions.

Meet The Newest Surgeon General

December 22, 2014 10:15 am | by Ryan Bushey, Associate Editor | Articles | Comments

President Obama's pick for the position turned out to be controversial.    ...

10 Up-and-Coming Healthcare Medical Innovations

December 17, 2014 5:32 pm | by Christina Jakubowski, Managing Editor | Articles | Comments

The Cleveland Clinic recently unveiled their annual Top 10 Medical Innovations for 2015– a list...

New Lens-Free Microscope Detects Cancer At Cellular Level

December 17, 2014 4:27 pm | by UCLA | News | Comments

Researchers have developed a lens-free microscope that can be used to detect the presence of...

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Women in Cell Biology Award Winners Announced at ASCB Meeting

December 17, 2014 10:05 am | by Stephanie Guzowski, Editor, Drug Discovery & Development | Articles | Comments

Three exceptional women were given awards for their achievements and contributions to the scientific community at the 2014 ASCB (American Society for Cell Biology) meeting recently held in Philadelphia, Pa.

Going After Colon Cancer With Strep Bacteria

December 17, 2014 9:40 am | by Skip Derra, Contributing Writer | Articles | Comments

A novel therapeutic to fight colon cancer by using the bacteria primarily responsible for causing strep throat is being explored in the labs of John McCormick of the Schulich School of Medicine & Dentistry at the University of Western Ontario, London, Ontario, Canada.

Interactions Between Proteins Govern Tumor Suppression, Aging

December 16, 2014 12:54 pm | by UC Davis | News | Comments

Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging.

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Technology Directly Reprograms Skin Cells for New Role

December 16, 2014 11:29 am | by University of Pennsylvania | News | Comments

Scientists have discovered a way to repurpose fibroblasts into functional melanocytes.                             

Proteins Drive Cancer Cells to Change States

December 16, 2014 11:12 am | News | Comments

A new study implicates a family of RNA-binding proteins in the regulation of cancer.                              

Cancer Patients Testing Drugs on Mouse Avatars

December 15, 2014 11:58 am | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

They are paying a private lab to breed mice that carry bits of their own tumors so treatments can be tried first on the customized rodents.                    

Signaling Mechanism Could be Target for Survival, Growth of Tumor Cells

December 15, 2014 11:54 am | by UT Southwestern | News | Comments

UT Southwestern Medical Center neurology researchers have identified an important cell signaling mechanism that plays an important role in brain cancer and may provide a new therapeutic target.                                 

Robotic Surgery Tool Treats Previously Inoperable Head and Neck Cancer

December 15, 2014 11:47 am | News | Comments

Researchers have advanced a robotic surgical technique to successfully access a previously unreachable area of the head and neck.                      

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Scientists Find Way to Boost Healthy Cells During Chemo

December 12, 2014 9:01 am | News | Comments

It’s well known that chemotherapy helps fight cancer. It’s also known that it wreaks havoc on normal, healthy cells. Scientists are closer to discovering a possible way to boost healthy cell production in cancer patients as they receive chemotherapy. 

Testosterone May Contribute to Colon Cancer Tumor Growth

December 11, 2014 8:30 am | News | Comments

Researchers have found evidence suggesting that the male hormone testosterone may actually be a contributing factor in the formation of colon cancer tumors.                           

Next Steps Uncertain for Women with Dense Breasts

December 9, 2014 8:30 am | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

More women are learning their breasts are so dense that it's more difficult for mammograms to spot cancer. But new research suggests automatically giving them an extra test isn't necessarily the solution.             

Injectable 3-D Vaccines Could Fight Cancer, Infectious Diseases

December 9, 2014 8:30 am | News | Comments

Researchers have shown a non–surgical injection of programmable biomaterial that spontaneously assembles in vivo into a 3-D structure could fight and even help prevent cancer and also infectious disease such as HIV.          

New Hope for Tackling Signs of Aging in the Future

December 8, 2014 3:08 pm | News | Comments

A new advance in biomedical research could have potential in the future to assist with tackling diseases and conditions associated with aging– as well as in treating cancer.                      

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Scientists Pinpoint a New Line of Defense Used by Cancer Cells

December 8, 2014 3:00 pm | Videos | Comments

Scientists have discovered a new line of defense used by cancer cells to evade cell death, according to new research. The team identified a critical pathway of molecular signals which throw a lifeline to cancer cells.         

Smoking Linked to Loss of Y Chromosome in Men

December 5, 2014 12:32 pm | News | Comments

In a new study, researchers demonstrated an association between smoking and loss of the Y chromosome in blood cells. The researchers have previously shown that loss of the Y chromosome is linked to cancer.          

Mediterranean Diet Has Marked Impact on Aging

December 3, 2014 3:42 pm | by Brigham and Women’s Hospital | News | Comments

The  Mediterranean diet consistently has been linked with an array of health benefits, including decreased risk of chronic disease and cancer. Until now, however, no studies had associated the diet with longer telomeres, one of the biomarkers of aging. Read more...

Relationship Between Sleep Cycle, Cancer Incidence

December 3, 2014 3:25 pm | News | Comments

People who work around the clock could actually be setting themselves back, according to Virginia Tech biologists. Researchers found that a protein responsible for regulating the body’s sleep cycle, or circadian rhythm, also protects the body from developing sporadic forms of cancers. Read more...

Detecting Gene Mutations Misses People at High Risk of Cancer

December 3, 2014 10:27 am | News | Comments

Research led by a University of Manchester academic on the BRCA gene mutation in the Jewish population shows that the current process of identifying people which relies on assessing someone’s family history, misses half the people who have the mutation and are at risk of developing cancer. Read more...

Current Mutation Detection Process Misses People at High Risk of Cancer

December 1, 2014 1:19 pm | News | Comments

New research on the BRCA gene mutation in the Jewish population shows that the current process of identifying people- which relies on assessing someone’s family history- misses half the people who have the mutation and are at risk of developing cancer.

Breast Cancer Vaccine Shows Promise in Small Trial

December 1, 2014 12:52 pm | News | Comments

A breast cancer vaccine developed at Washington University School of Medicine in St. Louis is safe in patients with metastatic breast cancer, results of an early clinical trial indicate.                   

Vegetable Oil Ingredient Key to Destroying Gastric Disease Bacteria

November 26, 2014 8:30 am | News | Comments

The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.     

Doctor Behind 'Free Radical' Aging Theory Dies

November 26, 2014 8:30 am | by Josh Funk - Associated Press - Associated Press | News | Comments

Dr. Denham Harman, a renowned scientist who developed the most widely accepted theory on aging that's now used to study cancer, Alzheimer's disease and other illnesses, has died in Nebraska at age 98.               

Exciting Gains in Fighting Breast Cancer Hormone-therapy Resistance

November 24, 2014 1:56 pm | by Cynthia Fox, Science Writer | Articles | Comments

Guided by breakthrough research on the Estrogen Receptor 1 (ESR1) gene, many researchers and pharmaceutical companies are in hot pursuit of the next big anti-resistance breast cancer drug.                  

Molecular Mapping Opens Doors to More Computer-Based Tests

November 18, 2014 1:28 pm | News | Comments

Scientists report a new method for establishing whether chemical compounds are safe for human use without in vivo testing. Read more...                     

Team Devises Method to Attack Cancer at Genetic Source

November 18, 2014 12:44 pm | News | Comments

Researchers designed a therapeutic molecule that both targets the acidic microenvironments of tumors and penetrates cells to deliver a therapeutic cargo. Read more...              

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