Researchers have found that the genetic mutation BRAFV600E , frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network of normal cells around the tumor to support the disease's progression.
For detecting cancer, manual breast exams seem low-tech compared to other methods such as MRI. But scientists are now developing an “electronic skin” that “feels” and images small lumps that fingers can miss.
Over the years researchers have made tremendous strides in the understanding and treatment of cancer by searching genomes for links between genetic alterations and disease. Now, a team of researchers has mined "junk DNA" sequences to identify a non-protein-coding RNA whose expression is linked to ovarian cancer.
A meta-analysis comprising 16 studies and 891,426 participants from various regions of the world shows that prediabetes increases the risk of cancer by 15 percent, with differing risks depending on the type of cancer.
Key discoveries about breast cancer, Parkinson's disease and the body's handling of defective proteins have earned prestigious medical awards for five scientists. The Albert and Mary Lasker Foundation announced the winners Monday.
Cancerous brain tumors are notorious for growing back despite surgical attempts to remove them. But scientists are currently developing a new way to try to root out malignant cells during surgery so fewer or none get left behind to form new tumors.
Removing both breasts to treat cancer affecting only one side doesn't boost survival chances for most women, compared with surgery that removes just the tumor, a large study suggests.
Circulating tumor cell clusters- clumps of from two to 50 tumor cells that break off a primary tumor and are carried through the bloodstream- appear to be much more likely to cause metastasis than are single CTCs, according to a new study.
Men who eat over 10 portions a week of tomatoes have an 18 per cent lower risk of developing prostate cancer, new research suggests. This is the first study of its kind to develop a prostate cancer "dietary index."
Regardless of their stage or type, cancers appear to share a telltale signature of widespread changes to the so-called epigenome, according to a team of researchers. In a study of a broad variety of cancers the investigators say they have found widespread and distinctive changes to chemical marks known as methyl groups attached to DNA.
Researchers have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel. Their device could be used to detect the extremely rare tumor cells that circulate in cancer patients’ blood.
Cancer, while always dangerous, truly becomes life-threatening when cancer cells begin to spread to different areas throughout the body. Now, researchers have discovered that a molecule used as a communication system by bacteria can be manipulated to prevent cancer cells from spreading.
A large new study found that when post-menopausal women stop physical activity, their odds of developing breast cancer rise. But, the study also found that breast cancer risk drops surprisingly rapidly after exercise starts.
Researchers have developed a new integrated approach to pinpoint the genetic “drivers” of cancer, uncovering eight genes that could be viable for targeted breast cancer therapy.
Research shows that nerves may play a critical role in stomach cancer growth and that blocking nerve signals using surgery or Botox (onabotulinumtoxinA) could be an effective treatment for the disease.
Scientists have made it easier to predict both breast cancer relapses and responses to chemotherapy, through the identification of a unique gene, a new study shows.
NGS is revolutionizing the field of genome biology, with much faster data generation, increased accuracy, and a dramatic reduction of sequencing costs. Multiple genomes can now be sequenced in parallel by a single instrument in a matter of days. In the medical field, NGS is already having an impact in genetic screening and holds great potential in oncology, given the genetic aspects of cancerous disease.
Links between a number of common respiratory diseases and an increased risk of developing lung cancer have been found in a large pooled analysis of seven studies involving more than 25,000 individuals.
Melbourne researchers have revealed the critical importance of highly specialized immune cells, called natural killer cells, in killing melanoma cells that have spread to the lungs. These natural killer cells could be harnessed to hunt down and kill cancers that have spread in the body.
A modified version of the Clostridium novyi (C. novyi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report.
In this episode of Bioscience Technology This Week, Rob Fee discusses how studying fruit flies could revolutionize diabetes research. Our second story focuses on how venom could form the basis of a new class of cancerfighting drugs.
Scientists have known for decades that cancer can be caused by genetic mutations, but more recently they have discovered that chemical modifications of a gene can also contribute to cancer. These alterations, known as epigenetic modifications, control whether a gene is turned on or off.
Oncologists are melding magnetic resonance imaging (MRI) technology with a traditional ultrasound prostate exam to create a three-dimensional map of the prostate that allows physicians to view growths that were previously undetectable.
Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have identified a gene that contributes to the development of several childhood cancers, in a study conducted with mice designed to model the cancers. If the findings prove to be applicable to humans, the research could lead to new strategies for targeting certain childhood cancers at a molecular level.
Researchers from The University of Texas at Austin and five other institutions have created a molecule that can cause cancer cells to self-destruct by ferrying sodium and chloride ions into the cancer cells. These synthetic ion transporters confirm a two-decades-old hypothesis that could point the way to new anticancer drugs while also benefiting patients with cystic fibrosis.