Cell biologists have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.
Scientists have identified a biological marker that may help predict survival in people with deadly brain tumors, showing that when the marker is present at higher levels, glioblastomas are more aggressive.
A gene important in skin tanning has been linked to higher risk for testicular cancer in white men, according to a study led by a team of international scientists.
A colorful wheel developed bioengineers to visualize protein interactions has won an international competition for novel strategies to study the roots of breast cancer.
Examining 12 major types of cancer, scientists have identified 127 repeatedly mutated genes that appear to drive the development and progression of a range of tumors in the body.
A team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.
What many commuters choking on smog have long suspected has finally been scientifically validated: air pollution causes lung cancer. The International Agency for Research on Cancer declared today that air pollution is a carcinogen.
Researchers have created a peptide, linked to a light-responsive dye, capable of switching "on" death pathways and altering critical interactions in B-cell lymphoma cancer cells.
Spraying a plant hormone on broccoli— already one of the planet’s most nutritious foods— boosts its cancer-fighting potential, and researchers say they have new insights on how that works.
Researchers have created a massive online database that matches thousands of genes linked to cancer and other diseases with various drugs that target those genes.
In a new study, researchers used a gene-array analysis known as "surprisal analysis," which uses the principles of thermodynamics, to identify cancer-specific gene signatures for breast, lung, prostate and ovarian cancers in more than 2,000 patients.
Researchers at Johns Hopkins have succeeded in making flattened, football-shaped artificial particles that impersonate immune cells. These football-shaped particles seem to be better than the typical basketball-shaped particles at teaching immune cells to recognize and destroy cancer cells in mice.
A recent study by a University of Missouri researcher shows that resveratrol, a compound found in grape skins and red wine, can make certain tumor cells more susceptible to radiation treatment. This research, which studied melanoma cells, follows a previous MU study that found similar results in the treatment of prostate cancer.
A gene that helps keep blood free of cancer is controlled by tiny pieces of RNA, a finding that may lead to better ways to diagnose blood cancers and even lead to new forms of treatment, researchers report.
A molecule originally implicated in DNA repair may also be a crucial factor in preventing tumors such as medulloblastoma, a type of childhood brain tumor, according to new research.
Findings from a study involving thousands of postmenopausal women suggest that women who use supplements containing both multivitamins and minerals have a 30 percent lower risk of dying from invasive breast cancer when compared with nonusers.
High levels of HDL have been linked to increased breast cancer risks and to enhanced cancer aggressiveness in animal experiments. Now, a team of researchers has shown that an HDL receptor found on breast cancer cells may be responsible for this effect.
Pancreatic cancer is typically diagnosed through an invasive and complicated biopsy. Now, in a study on a tumor-ridden mouse model, researchers were able to definitively validate that pancreatic cancer biomarkers reside in saliva.
A world-first human study to assess the impact of sunscreen at the molecular level has shown that sunscreen provides 100 percent protection against all three forms of skin cancer, and it also shields the important p53 gene, a gene that works to prevent cancer.
Often deadly “triple-negative” breast cancers might be effectively treated in many cases with a drug that targets a previously unknown vulnerability in the tumors, according to a new study. Researchers found blocking cystine from entering triple-negative breast cancer cells can significantly inhibited their growth in culture and when the cancer cells were transplanted into mice.
Researchers can now identify DNA regions within non-coding DNA, the major part of the genome that is not translated into a protein, where mutations can cause diseases such as cancer. Their approach reveals many potential genetic variants within non-coding DNA that drive the development of a variety of different cancers.
Postmenopausal women who were very active or walked for at least seven hours a week had a reduced risk for breast cancer, according to a study. This is the first study to report a lower risk for breast cancer among this demographic associated specifically with walking.
Cancerous tumors can shed cells that travel through the blood stream and create new cancerous growths. These seed cells can be very difficult to detect, but scientists are developing a noninvasive method using a mini-microscope that could find these cells.
Researchers have added a new layer of information to the Cancer Cell Line Encyclopedia related to the proteins around which DNA gets wrapped in the cell. This proteomics technique points the way to a potential drug target for pediatric acute lymphoblastic leukemia (ALL).
Scanning the DNA of nearly 5,000 tumor samples, a team of scientists has identified 140 regions of scrambled genetic code believed to contain many undiscovered cancer genes. The researchers said the mapping of the abnormal regions gives cancer scientists a starting point from which to search for as-yet undiscovered oncogenes and broken tumor-suppressor genes.