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Genetic Discovery Helps Guide Bladder Cancer Treatment

October 17, 2013 11:15 am | News | Comments

A team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.                      

Air Pollution Causes Cancer, Experts Say

October 17, 2013 5:30 am | by MARIA CHENG - AP Medical Writer - Associated Press | News | Comments

What many commuters choking on smog have long suspected has finally been scientifically validated: air pollution causes lung cancer. The International Agency for Research on Cancer declared today that air pollution is a carcinogen.     

Light Triggers Cancer Death Switch

October 16, 2013 2:34 pm | News | Comments

Researchers have created a peptide, linked to a light-responsive dye, capable of switching "on" death pathways and altering critical interactions in B-cell lymphoma cancer cells.                   

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Technique Can Boost Cancer-fighting Potential of Broccoli

October 16, 2013 1:57 pm | News | Comments

Spraying a plant hormone on broccoli— already one of the planet’s most nutritious foods— boosts its cancer-fighting potential, and researchers say they have new insights on how that works.                 

Database of Disease Genes IDs Drug Therapies

October 15, 2013 11:37 am | News | Comments

 Researchers have created a massive online database that matches thousands of genes linked to cancer and other diseases with various drugs that target those genes.                       

Thermodynamics May Help to Better Understand Cancers

October 15, 2013 11:26 am | News | Comments

In a new study, researchers used a gene-array analysis known as "surprisal analysis," which uses the principles of thermodynamics, to identify cancer-specific gene signatures for breast, lung, prostate and ovarian cancers in more than 2,000 patients.

Football-shaped Particles Bolster the Body's Defense against Cancer

October 14, 2013 10:42 am | News | Comments

Researchers at Johns Hopkins have succeeded in making flattened, football-shaped artificial particles that impersonate immune cells. These football-shaped particles seem to be better than the typical basketball-shaped particles at teaching immune cells to recognize and destroy cancer cells in mice.

Compound in Grapes, Red Wine Could Help Treat Multiple Types of Cancer

October 14, 2013 10:06 am | Videos | Comments

A recent study by a University of Missouri researcher shows that resveratrol, a compound found in grape skins and red wine, can make certain tumor cells more susceptible to radiation treatment. This research, which studied melanoma cells, follows a previous MU study that found similar results in the treatment of prostate cancer.

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Cancer-fighting Gene in Blood Controlled by RNA

October 11, 2013 12:03 pm | News | Comments

A gene that helps keep blood free of cancer is controlled by tiny pieces of RNA, a finding that may lead to better ways to diagnose blood cancers and even lead to new forms of treatment, researchers report.             

DNA Repair Molecule Helps Prevent Brain Tumors

October 11, 2013 11:49 am | News | Comments

A molecule originally implicated in DNA repair may also be a crucial factor in preventing tumors such as medulloblastoma, a type of childhood brain tumor, according to new research.                   

Multivitamins May Protect Against Breast Cancer Death

October 9, 2013 1:03 pm | News | Comments

Findings from a study involving thousands of postmenopausal women suggest that women who use supplements containing both multivitamins and minerals have a 30 percent lower risk of dying from invasive breast cancer when compared with nonusers.

Good Cholesterol May Increase Breast Cancer Risk

October 9, 2013 11:42 am | News | Comments

High levels of HDL have been linked to increased breast cancer risks and to enhanced cancer aggressiveness in animal experiments. Now, a team of researchers has shown that an HDL receptor found on breast cancer cells may be responsible for this effect.

Tumors, Saliva Exchange Cellular Signals

October 9, 2013 11:36 am | News | Comments

Pancreatic cancer is typically diagnosed through an invasive and complicated biopsy. Now, in a study on a tumor-ridden mouse model, researchers were able to definitively validate that pancreatic cancer biomarkers reside in saliva.    

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Sunscreen Saves 'Superhero' Gene

October 8, 2013 12:10 pm | News | Comments

A world-first human study to assess the impact of sunscreen at the molecular level has shown that sunscreen provides 100 percent protection against all three forms of skin cancer, and it also shields the important p53 gene, a gene that works to prevent cancer.

Drug Can Target Deadly Breast Cancer

October 4, 2013 1:40 pm | News | Comments

Often deadly “triple-negative” breast cancers might be effectively treated in many cases with a drug that targets a previously unknown vulnerability in the tumors, according to a new study.  Researchers found blocking cystine from entering triple-negative breast cancer cells can significantly inhibited their growth in culture and when the cancer cells were transplanted into mice.

'Junk' DNA Reveals New Disease-causing Mutations

October 4, 2013 12:22 pm | News | Comments

Researchers can now identify DNA regions within non-coding DNA, the major part of the genome that is not translated into a protein, where mutations can cause diseases such as cancer. Their approach reveals many potential genetic variants within non-coding DNA that drive the development of a variety of different cancers.

Walking Can Reduce Breast Cancer Risk

October 4, 2013 11:52 am | News | Comments

Postmenopausal women who were very active or walked for at least seven hours a week had a reduced risk for breast cancer, according to a study. This is the first study to report a lower risk for breast cancer among this demographic associated specifically with walking.

Mini-microscope Detects Cancer Seeds Early

October 1, 2013 12:02 pm | News | Comments

Cancerous tumors can shed cells that travel through the blood stream and create new cancerous growths. These seed cells can be very difficult to detect, but scientists are developing a noninvasive method using a mini-microscope that could find these cells. 

Proteomics Adds New Chapter to ALL Research

September 29, 2013 2:22 pm | by Broad Institute of MIT and Harvard | News | Comments

Researchers have added a new layer of information to the Cancer Cell Line Encyclopedia related to the proteins around which DNA gets wrapped in the cell. This proteomics technique points the way to a potential drug target for pediatric acute lymphoblastic leukemia (ALL).

On the Hunt for Undiscovered Cancer Genes

September 27, 2013 1:56 pm | by Harvard Medical School | News | Comments

Scanning the DNA of nearly 5,000 tumor samples, a team of scientists has identified 140 regions of scrambled genetic code believed to contain many undiscovered cancer genes. The researchers said the mapping of the abnormal regions gives cancer scientists a starting point from which to search for as-yet undiscovered oncogenes and broken tumor-suppressor genes.

Telomere Length May Matter for Prostate Cancer Prognosis

September 27, 2013 1:16 pm | News | Comments

Like the plastic caps at the end of shoelaces, telomeres protect- in their case- the interior-gene containing parts of chromosomes that carry a cell's instructional material. Cancer cells are known to have short telomeres, but just how short they are from cancer cell to cancer cell may be a determining factor in a prostate cancer patient's prognosis, according to a new study.

New Breast Cancer Imaging Technique Can Minimize False Positives

September 27, 2013 12:46 pm | News | Comments

A joint research team is developing a new breast cancer screening technique that has the potential to reduce false positives, and, possibly, minimize the need for invasive biopsies. The new MRI device could improve both the process and accuracy of breast cancer screening by scanning for sodium levels in the breast.

Study IDs Rules for Cancer Drivers

September 27, 2013 6:22 am | News | Comments

This week, researchers announced that they had identified some rules that apply across cancers for a specific type of genetic mutation– somatic copy number alterations (SCNAs). SCNAs are deletions or duplications of certain regions of the genome, and are some of the most common mutations that occur in cancer.

Eating Peanut Butter May Improve Breast Health Later in Life

September 26, 2013 12:14 pm | News | Comments

Here’s some news worth spreading: Girls who eat more peanut butter could improve their breast health later in life. Research shows that girls ages 9 to 15 who regularly ate peanut butter or nuts were 39 percent less likely to develop benign breast disease by age 30.

Hospital First to Test All Patients for Millions of Tumor Mutations

September 25, 2013 1:13 pm | by Cynthia Fox | Articles | Comments

“Incredibly valuable,” is how Barrett Rollins, Chief Scientific Officer of the Dana Farber Cancer Institute, describes his hospital’s unprecedented Profile program. In that program, the largest of its kind, all adult cancer patients at two Boston hospitals—Dana Farber and Brigham Women’s—are offered some of the most extensive, next-generation-sequencing (NGS) testing in existence.

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