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Microarray for Research into Haematological and Solid Cancers

May 9, 2014 1:18 pm | Product Releases | Comments

Oxford Gene Technology (OGT) released a new microarray designed to improve the accuracy and efficiency of cancer research. The CytoSure Cancer +SNP array (4x180k) combines long oligo array comparative genomic hybridisation (aCGH) probes with fully validated single nucleotide polymorphism (SNP) content.

App Offers Quick, Inexpensive Melanoma Screening

May 7, 2014 1:00 pm | News | Comments

An app called DermoScreen, which would allow users to take a photo of a suspicious mole or lesion with your phone, run it through an embedded software program and find out within a few seconds if it is likely to be cancerous, is currently being evaluated for further testing.

'Bad' Cholesterol Helps Cancer Spread

May 7, 2014 12:48 pm | News | Comments

In a world-first, researchers have discovered one of the main reasons behind why cancer spreads throughout the body: the help of "bad" cholesterol. The research found that LDL regulates the machinery that controls cell migration.       

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Having Eczema May Reduce Skin Cancer Risk

May 6, 2014 12:31 pm | News | Comments

Eczema caused by defects in the skin could reduce the risk of developing skin cancer, according to new research. The immune response triggered by eczema could help prevent tumor formation by shedding potentially cancerous cells from the skin.   

30-year Puzzle in Breast Cancer Solved

May 2, 2014 1:29 pm | News | Comments

Scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer. CTCF is a very well-studied DNA binding protein that exerts a major influence on the architecture of the human genome, but had not been previously linked to cancer.

Novel Regulator of Key Gene Expression in Cancer Identified

May 1, 2014 1:58 pm | News | Comments

Scientists identified a key genetic switch linked to the development, progression and outcome of cancer, a finding that may lead to new targets for cancer therapies. The switch, a string of nucleotides dubbed a long non-coding RNA (lncRNA), does not code for proteins like regular RNA. Instead, this particular lncRNA acts as an on/off switch for a key gene whose excessive activity is tied to inflammation and cancer, COX-2.

Vitamin D Deficiency May Be Linked to Aggressive Prostate Cancer

May 1, 2014 1:46 pm | News | Comments

Vitamin D deficiency was an indicator of aggressive prostate cancer and spread of the disease in European-American and African-American men who underwent their first prostate biopsy because of abnormal prostate-specific antigen and/or digital rectal examination test results, according to a study.

Human Fat: A Trojan Horse to Fight Brain Cancer?

May 1, 2014 1:13 pm | News | Comments

Researchers have successfully used stem cells derived from human body fat to deliver biological treatments directly to the brains of mice with glioblastomas, the most common and aggressive form of brain tumor, significantly extending their lives.

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Breast Cancer Clue

April 30, 2014 12:43 pm | News | Comments

Inherited mutations in the BRCA1 or BRCA2 tumor suppressor genes are by far the most frequent contributors to hereditary cancer risk in the human population. Now, investigators are reporting a new mechanism by which BRCA gene loss may accelerate cancer-promoting chromosome rearrangements.

Researchers ID 'Master Regulator' Role for Protein in Cancer Cells

April 30, 2014 12:29 pm | News | Comments

Researchers found that the protein DAZAP1 plays a key role in the regulation of many genes through a process known as alternative splicing, and when highly expressed in cancer cell line experiments, DAZAP1 was shown to inhibit several types of cancer cells from dividing and moving.

Secrets Behind Health Benefits of Wine Revealed

April 29, 2014 12:22 pm | News | Comments

Scientists have identified one of the molecular pathways that resveratrol, the component of grapes and red wine associated with health benefits, uses to achieve its beneficial action.                   

Researchers ID Potential New Strategy to Treat Ovarian Cancer

April 28, 2014 1:33 pm | News | Comments

Scientists studying cancerous tumor tissues in a laboratory believe they have identified a potential new strategy to treat ovarian cancer by targeting ovarian tumor growth through the inhibition of the development of new tumor blood vessels.   

Cancer Researchers Can Create Live Tumors with 3-D Printer

April 25, 2014 12:32 pm | News | Comments

Using a mixture of cervical cancer cells and a hydrogel substance that resembles an ointment balm, an engineer has devised a method for 3-D printing tumors that could soon be taking cancer research out of the petri dish.         

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FDA OKs First-ever DNA Alternative to Pap Smear

April 24, 2014 3:20 pm | by Matthew Perrone - AP Health Writer | News | Comments

Federal health regulators have cleared a genetic test from Roche as a first-choice screening option for cervical cancer. It was a role previously reserved for the Pap smear, the decades-old mainstay of women's health.         

Breast Cancer Replicates Brain Development Process

April 24, 2014 1:12 pm | News | Comments

New research reveals that a process that forms a key element in the development of the nervous system may also play a pivotal role in the spread of breast cancer.                      

Gene Determines If Aspirin Can Lower Colon Cancer Risk

April 24, 2014 1:00 pm | News | Comments

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene.     

Triclosan Spurs Growth of Breast Cancer Cells

April 23, 2014 1:01 pm | News | Comments

Some manufacturers are turning away from using triclosan as an antimicrobial ingredient in soaps, toothpastes and other products over health concerns. Now, scientists are reporting new evidence that appears to support these worries.     

MRI Sensor Tracks Oxygen in the Body

April 23, 2014 12:49 pm | News | Comments

Measuring tumors’ oxygen levels could help doctors make decisions about treatments, but there’s currently no reliable, noninvasive way to make such measurements. However, a new an injectable device that reveals oxygen levels over several weeks could change that.

Enzymes Can Help Fix Cancer-causing DNA Defects

April 23, 2014 12:40 pm | News | Comments

Researchers have identified an important enzyme pathway that helps prevent new cells from receiving too many or too few chromosomes, a condition that has been directly linked to cancer and other diseases.             

Cancer Spread’s ‘Family Tree’

April 23, 2014 12:34 pm | News | Comments

The process of metastasis is still poorly understood. Now, a research team has developed a simple test that can reveal the evolutionary relationships among various tumor sites within a patient, information that may someday help with treatment planning.

Killing Cancer on the Run

April 22, 2014 3:30 pm | by Skip Derra | Articles | Comments

A dream solution to cancer metastasis has been to develop a method that can track and kill the cancer cells that are on the move. The complexity at which those cancer cells operate has long been a formidable obstacle to stopping metastases, which cause 90 percent of cancer deaths, but that may change. 

Fast Way to Measure DNA Repair

April 22, 2014 2:57 pm | News | Comments

A team of researchers has developed a test that can rapidly assess several DNA repair systems, which could help determine individuals’ risk of developing cancer and help doctors predict how a given patient will respond to chemotherapy drugs.   

Cancer Stem Cells Linked to Drug Resistance

April 21, 2014 2:25 pm | News | Comments

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers have discovered a biomarker called CD61 that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.

Scientists ID Source of Most Bladder Cancer Cases

April 21, 2014 2:15 pm | News | Comments

A single type of cell in the lining of the bladder is responsible for most cases of invasive bladder cancer, according to researchers. This study is the first to pinpoint the normal cell type that can give rise to invasive bladder cancers.   

Down Syndrome, Leukemia Link Uncovered

April 21, 2014 11:48 am | News | Comments

Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven’t been able to explain why. Now, a team investigators has uncovered a connection between the two conditions.

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