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Scientists Finally ID Which Prostate Cancers are Life Threatening

November 19, 2013 12:03 pm | News | Comments

Scientists have discovered that the presence of a specific protein can distinguish between prostate cancers that are aggressive and need further treatment from those that may never seriously harm the patient.             

Manipulation of Protein Could Help Stop Spread of Cancer Cells

November 18, 2013 2:28 pm | News | Comments

Understanding how and why cancer cells move away from their original location is important to find ways to stop the spread of the disease. New findings reveal how a protein, called ‘PRH’, is normally able to prevent cells from unnecessary migration. It is likely that this protein is less effective in cancer cells allowing the cells to venture away.

Body’s Natural Defense Carries Early Warning System for Recurring Cancers

November 18, 2013 1:56 pm | News | Comments

Scientists have found that the immune system’s behavior can act as an early warning alarm that detects cancer recurrence, and this could offer a chance for pre-emptive treatment before the disease takes hold for the second time. The study, in mice, involved researchers looking for early signs of the immune response ‘kicking in’ indicating that the cancer was once more awake.

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Scientists Fingerprint Single Cancer Cells to Map Cancer’s Family Tree

November 18, 2013 1:51 pm | News | Comments

A new method to take the DNA fingerprint of individual cancer cells is uncovering the true extent of cancer’s genetic diversity, new research reveals. The technique can identify the founding mutations from which a tumor evolved and then uses computer software to draw a map of the cancer’s family tree.

Mutations of Immune System Found in Breast Cancers

November 18, 2013 1:27 pm | News | Comments

Mutations in the genes that defend the body against cancer-related viruses and other infections may play a larger role in breast cancer than previously thought. A researcher looked at the DNA sequences of breast cancers from 21 different women and found mutations in genes involved in immunity in every one of them. The mutations were each different, but all would have affected some aspect of pathogen recognition and defense.

Two-step Method Promising in Pancreatic Cancer Fight

November 15, 2013 12:54 pm | News | Comments

Researchers have developed a new technique for fighting deadly and hard-to-treat pancreatic cancer that uses two different types of nanoparticles, the first type clearing a path into tumor cells for the second, which delivers chemotherapy drugs. 

Some Investigational Cancer Drugs Can Fuel Tumor Growth

November 12, 2013 12:01 pm | News | Comments

Researchers studying how cancer spreads into bone have made a surprising discovery that suggests several investigational anti-cancer therapies just entering the drug-development pipeline may not have the desired effect.         

One Dose of HPV Vaccine May Be Enough to Prevent Cervical Cancer

November 4, 2013 1:48 pm | News | Comments

Women vaccinated with one dose of a human papillomavirus (HPV) vaccine had antibodies against the viruses that remained stable in their blood for four years, suggesting that a single dose of vaccine may be sufficient to generate long-term immune responses and protection against new HPV infections, and ultimately cervical cancer.

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Implantable Sensor Paves Way to Long-term Monitoring

November 4, 2013 1:02 pm | News | Comments

Nitric oxide (NO) is one of the most important signaling molecules in living cells, carrying messages within the brain and coordinating immune system functions. In many cancerous cells, levels are perturbed, but very little is known about how NO behaves in both healthy and cancerous cells.

Why Tumor Cells Go on Dangerous Tours

November 4, 2013 12:54 pm | News | Comments

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Ludwig-Maximilians-Universität München researchers have identified a factor that promotes metastasis of colon tumors – and presents a possible target for therapy.

Method Can Kill Drug-resistant Cancer Cells

November 1, 2013 12:41 pm | News | Comments

Cisplatin is a chemotherapy drug given to more than half of all cancer patients. The drug kills cells very effectively, but tumors can become resistant to the drug and grow back. A new study offers a possible way to overcome that resistance.   

Scientists ID Protein Crucial to Cancer Survival

November 1, 2013 12:30 pm | News | Comments

Scientists have demonstrated that that cancer cells need a protein called Bod1 to grow and divide. When this protein is removed, cancer cells lose control of cell division and die.                    

Bone Drug Kills Leukemia in Mice

November 1, 2013 10:00 am | by Harvard Medical School | News | Comments

A bone drug already on the market for osteoporosis may kill chronic myelogenous leukemia (CML) stem cells thought to persist in the bone marrow after standard therapy, lowering the likelihood of disease recurrence, according to a new study.

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New Microbream Emitter Makes MRT Easier

October 31, 2013 1:38 pm | News | Comments

Research into clinical use of microbeam radiation therapy (MRT) has been limited because of the sheer size of the technology required to generate the beams. Now, researchers have developed a new microbeam emitter which has scaled down the technology, opening the doors for clinical research.    

Breaking News: New Theory of Cancer Development

October 31, 2013 12:07 pm | News | Comments

Researchers have devised a new way to understand patterns of aneuploidy in tumors and have proposed that the phenomenon is a driver of cancer, rather than a result of it.                     

Breaking News: Incurable Brain Cancer Gene Silenced

October 30, 2013 2:10 pm | News | Comments

A research team demonstrated, for the first time, delivery of a drug that turns off a critical gene in the aggressive and incurable glioblastoma multiforme, increasing survival rates significantly in animals with the deadly disease.       

HPV Strains Affecting African-American Women Differ from Vaccines

October 29, 2013 12:13 pm | News | Comments

Two subtypes of human papillomavirus (HPV) prevented by vaccines are half as likely to be found in African-American women as in white women with precancerous cervical lesions, according to researchers.              

New Genetic Error Found in Lung Cancers

October 28, 2013 12:07 pm | News | Comments

A fine-grained scan of DNA in lung cancer cells has revealed a gene fusion– a forced merger of two normally separate genes– that spurs the cells to divide rapidly, scientists report.                    

Targeting Cancer's 'Queen Bees' with Better Tissue Modeling

October 27, 2013 2:22 pm | by Broad Institute of MIT and Harvard | News | Comments

Hunting for compounds that target the cancer stem cells of the blood cancer acute myeloid leukemia (AML) is now easier thanks to work by a team of scientists who built a new cell culture model that mimics AML in its niche in the bone marrow and makes the search for promising new drugs more effective.

New Method for Diagnosing Breast Cancer

October 25, 2013 12:37 pm | News | Comments

According to a new study, a novel mammography procedure could generate substantial added-value for the diagnosis of breast cancer in medical practice.                             

Doubling Forces to Extend Glioblastoma Survival

October 25, 2013 11:53 am | News | Comments

A novel combination of two oral targeted drugs dramatically slowed the growth of glioblastoma brain tumors in mice and significantly extended the animals’ survival, scientists report.                   

New Breast Cancer Risk Gene Discovered

October 24, 2013 11:54 am | News | Comments

A new breast cancer risk gene has been discovered which explains the early-onset breast cancer in some multiple-case breast cancer families.                               

Decision Circuit of Cancer Metastasis Decoded

October 24, 2013 11:40 am | News | Comments

Cancer researchers have deciphered the operating principles of a genetic switch that cancer cells use to decide when to metastasize and invade other parts of the body.                       

Epigenetic Blood Test May Catch Early Pancreatic Cancer

October 23, 2013 1:33 pm | News | Comments

In a small preliminary study, researchers say a blood test based on detection of epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always fatal because of its late diagnosis.       

Obesity Lowers Pancreatic Cancer Survival Rates

October 22, 2013 12:56 pm | News | Comments

New study results show that patients with a body mass index (BMI) in the obese range live on average two to three months less after a pancreatic cancer diagnosis when compared with healthy weight patients.             

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