Scientists have demonstrated that that cancer cells need a protein called Bod1 to grow and divide. When this protein is removed, cancer cells lose control of cell division and die.
A bone drug already on the market for osteoporosis may kill chronic myelogenous leukemia (CML) stem cells thought to persist in the bone marrow after standard therapy, lowering the likelihood of disease recurrence, according to a new study.
Research into clinical use of microbeam radiation therapy (MRT) has been limited because of the sheer size of the technology required to generate the beams. Now, researchers have developed a new microbeam emitter which has scaled down the technology, opening the doors for clinical research.
Researchers have devised a new way to understand patterns of aneuploidy in tumors and have proposed that the phenomenon is a driver of cancer, rather than a result of it.
A research team demonstrated, for the first time, delivery of a drug that turns off a critical gene in the aggressive and incurable glioblastoma multiforme, increasing survival rates significantly in animals with the deadly disease.
Two subtypes of human papillomavirus (HPV) prevented by vaccines are half as likely to be found in African-American women as in white women with precancerous cervical lesions, according to researchers.
A fine-grained scan of DNA in lung cancer cells has revealed a gene fusion– a forced merger of two normally separate genes– that spurs the cells to divide rapidly, scientists report.
Hunting for compounds that target the cancer stem cells of the blood cancer acute myeloid leukemia (AML) is now easier thanks to work by a team of scientists who built a new cell culture model that mimics AML in its niche in the bone marrow and makes the search for promising new drugs more effective.
According to a new study, a novel mammography procedure could generate substantial added-value for the diagnosis of breast cancer in medical practice.
A novel combination of two oral targeted drugs dramatically slowed the growth of glioblastoma brain tumors in mice and significantly extended the animals’ survival, scientists report.
A new breast cancer risk gene has been discovered which explains the early-onset breast cancer in some multiple-case breast cancer families.
Cancer researchers have deciphered the operating principles of a genetic switch that cancer cells use to decide when to metastasize and invade other parts of the body.
In a small preliminary study, researchers say a blood test based on detection of epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always fatal because of its late diagnosis.
New study results show that patients with a body mass index (BMI) in the obese range live on average two to three months less after a pancreatic cancer diagnosis when compared with healthy weight patients.
To identify the molecular alterations responsible for mantle cell lymphoma, a group of scientists has sequenced the genome of more than thirty lymphomas- the first comprehensive genomic analysis of the disease.
To overcome triple negative breast cancer's eventual resistance to drugs, chemical engineers have designed nanoparticles that now only carry a cancer drug, but also carry short strands of RNA that can shut off one of the genes that cancer cells use to escape the drug.
Coffee consumption reduces risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, by about 40 percent, according to new research.
Changes in CA125 blood levels—not one-shot tests—may be the key to one of oncology’s most elusive goals: identifying ovarian cancer at a treatable stage, says a recent Cancer study. By measuring such changes, the study, conducted by MD Anderson Cancer Center, identified women who needed intensive monitoring, and those who don’t.
Cell biologists have teased apart two integral components of the machinery that causes cells to move. Their discovery shows that cellular projections, which act as hands to help a cell "crawl," are apparently always initiated by a network of message-relaying proteins inside the cell.
Scientists have identified a biological marker that may help predict survival in people with deadly brain tumors, showing that when the marker is present at higher levels, glioblastomas are more aggressive.
A gene important in skin tanning has been linked to higher risk for testicular cancer in white men, according to a study led by a team of international scientists.
A colorful wheel developed bioengineers to visualize protein interactions has won an international competition for novel strategies to study the roots of breast cancer.
Examining 12 major types of cancer, scientists have identified 127 repeatedly mutated genes that appear to drive the development and progression of a range of tumors in the body.
A team of scientists has discovered that a gene mutation found in some bladder cancers is indicative of low-risk tumors that are unlikely to recur or progress after surgery.
What many commuters choking on smog have long suspected has finally been scientifically validated: air pollution causes lung cancer. The International Agency for Research on Cancer declared today that air pollution is a carcinogen.