Chemotaxis slide allows the motion tracking of slow migrating cells like chemotactic active cancer cells in gradients. Up until now, comparable cell-based assays have only allowed the tracking of fast migrating cells such as neutrophiles or dictiostelia.
TissueScan is an RT-PCR based system for fast and accurate gene expression profiling across a large number of cancer patient samples. High-quality cDNAs were prepared from 48 well-documented cancer biopsy samples, normalized and assembled into ready-to-use gene expression panels.
DNA methylation markers are a new and important class of biomarkers that are significant because of their correlation to gene activity. High levels of cytosine methylation in genomic regions (CpG islands) are often associated with decreased or completely inhibited gene expression.
ArrayAssist Copy Number Software (Stratagene Corp.) enables manipulation and analysis of the massive data sets generated by chromosomal copy number microarrays. All ArrayAssist applications offer GeneChip-compatible status with the Affymetrix platform.
A flexible, high-throughput DNA methylation profiling technology has been introduced that is capable of surveying up to 1,536 methylation sites across 96 samples simultaneously. Illumina Inc.
The PALM MicroBeam laser microdissection system provides for non-contact (contamination-free) isolation of homogeneous specimens from tissue or the acquisition of living cells, which facilitates the molecular analysis of DNA, RNA and proteins.
A diverse selection of cyclin-dependent kinase (CDK) inhibitors is available from Axxora. The family of inhibitors consists of over 35 reagents, including selective inhibitors for CDK-1, CDK-2, CDK-4, CDK-5, and GSK-3B as well as other enzymes.
Listing of awarded and available funding
Source: The University of Texas Southwestern Medical Center, Dallas
Source: Dana-Farber Cancer Institute, Boston
Listing of licensing and service agreements
Source: National Cancer Institute, Bethesda, Md.
Source: Cedars-Sinai Medical Center, Los Angeles
Source: Vanderbilt University Medical Center, Nashville
Source: Beth Israel Deaconess Medical Center, Boston
Source: State University of New York at Buffalo
Listing of drug developments and approvals
Source: Mayo Clinic, Rochester, Minn.
Source: University of North Carolina, Chapel Hill
Source: St. Jude Children's Research Hospital, Memphis, Tenn.
The rate of cancer incidence continues to remain stable while the death rate from cancer continues to decline, states the 2005 Cancer Trends Progress Report Update, published by the National Cancer Institute (NCI).
Source: Lustgarten Foundation for Pancreatic Cancer Research, Bethpage, N.Y.
The benefits of automating biological assays include the elimination of problems introduced through human error, increased throughput and consistency, and decreased costs.
MHC Class II Ultimers facilitate evaluation and characterization of CD4+ single antigen-specific T cells, enabling evaluation of the T cell immune response in a wide range of disease areas including, autoimmune disease, cancer and infectious diseases.