Guided by breakthrough research on the Estrogen Receptor 1 (ESR1) gene, many researchers and pharmaceutical companies are in hot pursuit of the next big anti-resistance breast cancer drug.
Scientists report a new method for establishing whether chemical compounds are safe for human use without in vivo testing. Read more...
Researchers designed a therapeutic molecule that both targets the acidic microenvironments of tumors and penetrates cells to deliver a therapeutic cargo. Read more...
Scientists have discovered mechanisms that control a new form of premature cell death in living tissue and a mechanism to reverse it. Read more...
Scientists have uncovered how the massive DNA molecules that appear in some tumors are formed like Frankenstein’s monster, stitched together from other parts of the genome.
Researchers say they have identified first steps in the origin of pancreatic cancer and that their findings suggest preventive strategies to explore. In a new study, the scientists described the molecular steps necessary for acinar cells in the pancreas to become precancerous lesions.
Most cancer deaths occur because of metastasis, yet progress in preventing and treating migratory cancer cells has been slow. Scientists have now identified a cellular culprit that should help researchers better understand how metastasis begins.
Researchers are building an entire technology around tiny, microscopic bubbles– a technology that has the potential to play an important role in diagnosing as well as treating disease like stroke and cancer.
Genetically engineering tumors in mice, a technique that has dominated cancer research for decades, may not replicate important features of cancers caused by exposure to environmental carcinogens, according to a new study.
A multicenter team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme a promising therapeutic target.
Through a new, semi-secretive extension of the company, Google is working on a slew of ambitious projects that could drastically revolutionize healthcare as we know it.
A group of scientists has fused the power of statistical physics and artificial intelligence into a mathematical toolkit that can turn cancer-mutation data into multidimensional models that show how specific mutations alter the social networks of proteins in cells.
Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study has found. The findings suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy.
A team of showed that it is possible to detect, in patients at risk of developing lung cancer, early signs of disease several months, and in some cases several years, before the cancer becomes detectable by CT scanning.
If melanoma, the deadliest form of skin cancer, is caught early enough it is almost always curable. Now, a camera capable of taking snapshots of the entire human body and rendering high-resolution images of a patient’s skin may help doctors spot cancer early and save lives.
Should every newborn baby girl be genetically screened for breast-cancer risk? That isn’t cost-effective— yet. But if it were, would it be worthwhile? A previous study said no. But, new research suggests otherwise.
Google is working on a cancer-detecting pill in its latest effort to push the boundaries of technology. Still in the experimental stage, the pill is packed with tiny magnetic particles, which can travel through a patient's bloodstream, search for malignant cells and report their findings to a sensor on a wearable device.
A multi-institutional, international team of researchers studied cells found in breast and other types of connective tissue and discovered new information about cell transitions that take place during wound healing and cancer.
Radiotherapy is a primary, adjuvant or neoadjuvant treatment for a number of different cancers, such as glioblastoma, breast, lung and prostate. Image-guided radiation therapy (IGRT) is used to reduce the amount of radiation delivered to the normal tissue surrounding the targeted tumor. However, in the preclinical setting, the use of IGRT is less common.
Two recent papers may have upturned two common beliefs about adult stem cells: One reported that there appears to be stem cells in the esophagus, while the other reported that a fetal stem cell that can become either a liver cell or an endothelial cell.
Starting Monday, millions of people who have avoided colon cancer screening can get a new home test that's noninvasive and doesn't require the icky preparation most other methods do. The test is the first to look for cancer-related DNA in stool.
A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients.
Physicians will tell you: They are not winning the war on ovarian cancer. But researchers have combined medicine and advanced nanotechnological engineering to create a smarter, more targeted therapy that could overcome the most lethal gynecologic cancer.
Researchers now developed a new way to model the effects of these genetic mutations in mice. The approach, based on the genome-editing technique known as CRISPR, is much faster than existing strategies, which require genetically engineering mice that carry the cancerous mutations.