Some of the most important advances in breast cancer this year were related to all kinds of heterogeneity: within tumors, between tumors in a single patient, and between tumors in early and later stages, according to oncologists speaking at conferences, and contacted by Bioscience Technology.
Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell’s “biological clock” to kill cancer cells and shrink tumor growth.
Scientists from the Johns Hopkins Kimmel Cancer Center have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused mainly by random mutations that occur when stem cells divide.
The body has evolved ways to get rid of faulty stem cells.
Cancer Research UK scientists have taken microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells - meaning they can break loose and spread, according to research published in Cell Reports.
An international research team, including four Simon Fraser University scientists, has identified the "mutational landscape" of intrahepatic cholangiocarcinoma (ICC), a rare, highly fatal form of liver cancer that disproportionately affects people in Asian countries.
UT Southwestern Medical Center cancer researchers have demonstrated that whole-genome sequencing can be used to identify patients' risk for hereditary cancer, which can potentially lead to improvements in cancer prevention, diagnosis, and care.
Scientists at The Scripps Research Institute have found that this red-wine ingredient once touted as an elixir of youth, powerfully activates an evolutionarily ancient stress response in human cells.
Developing effective treatments for lung cancer has been challenging, in part because so many genetic mutations play a role in the disease. By analyzing the DNA and RNA of lung cancers, researchers at the University of Michigan Comprehensive Cancer Center found that patients whose tumors contained a large number of gene fusions had worse outcomes than patients with fewer gene fusions.
President Obama's pick for the position turned out to be controversial.
The Cleveland Clinic recently unveiled their annual Top 10 Medical Innovations for 2015– a list that casts an optimistic light on up-and-coming healthcare advances that may reach consumers next year.
Researchers have developed a lens-free microscope that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes.
Three exceptional women were given awards for their achievements and contributions to the scientific community at the 2014 ASCB (American Society for Cell Biology) meeting recently held in Philadelphia, Pa.
A novel therapeutic to fight colon cancer by using the bacteria primarily responsible for causing strep throat is being explored in the labs of John McCormick of the Schulich School of Medicine & Dentistry at the University of Western Ontario, London, Ontario, Canada.
Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. Too little Rbm38 allows p53 overexpression, causing premature aging.
Scientists have discovered a way to repurpose fibroblasts into functional melanocytes.
A new study implicates a family of RNA-binding proteins in the regulation of cancer.
They are paying a private lab to breed mice that carry bits of their own tumors so treatments can be tried first on the customized rodents.
UT Southwestern Medical Center neurology researchers have identified an important cell signaling mechanism that plays an important role in brain cancer and may provide a new therapeutic target.
Researchers have advanced a robotic surgical technique to successfully access a previously unreachable area of the head and neck.
It’s well known that chemotherapy helps fight cancer. It’s also known that it wreaks havoc on normal, healthy cells. Scientists are closer to discovering a possible way to boost healthy cell production in cancer patients as they receive chemotherapy.
Researchers have found evidence suggesting that the male hormone testosterone may actually be a contributing factor in the formation of colon cancer tumors.
More women are learning their breasts are so dense that it's more difficult for mammograms to spot cancer. But new research suggests automatically giving them an extra test isn't necessarily the solution.
Researchers have shown a non–surgical injection of programmable biomaterial that spontaneously assembles in vivo into a 3-D structure could fight and even help prevent cancer and also infectious disease such as HIV.
A new advance in biomedical research could have potential in the future to assist with tackling diseases and conditions associated with aging– as well as in treating cancer.