Researchers have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions.
The U.S. Food and Drug Administration has approved a first-of-a-kind breast cancer medication that targets tumor cells while sparing healthy ones. The drug Kadcyla from Roche combines the established drug Herceptin with a powerful chemotherapy drug and a third chemical linking the medicines...
New research argues that prolonged chemotherapy decreases the development of new brain cells and disrupts ongoing brain rhythms in the part of the brain responsible for making new memories.
A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study. The discovery might one day lead to better forms of treatment for patients with MS.
If a genome is the blueprint for life, then the chief architects are tiny slices of genetic material that orchestrate how we are assembled and function, researchers report.
A new study shows that resistant starch helps the body resist colorectal cancer through mechanisms including killing pre-cancerous cells and reducing inflammation that can otherwise promote cancer.
A team of researchers has shown that the concept of how the speed of creation affects performance also applies to how a protein they studied impacts circadian clock function.
Diagnostics maker Cepheid said Tuesday it will work with Oregon Health & Science University to develop tests that predict the risk of recurrence of breast and prostate cancer. Cepheid said it will work with OHSU's Knight Cancer Institute. The tests will run on the Cepheid GeneXpert system....
Reports that milk in the Balkans has been contaminated by a cancer-causing toxin have triggered a major health scare throughout the region, with authorities appealing for calm before official tests are conclusive. Senior agriculture official Goran Jesic claims on his website that out of 35 tested...
Shares of Pharmacyclics Inc. climbed to an all-time high Friday after the company said it expects to file for marketing approval of its cancer drug ibrutinib this year. If approved, it would be Pharmacyclics first drug for sale.
Researchers have identified a family of human genes known as Tousled-like kinases (TLKs) that play a key role in the suppression and activation of Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV).
Researchers have adapted natural mechanisms in living organisms to detect specific molecules, such as cocaine, more accurately and quickly. Their work may greatly facilitate the rapid screening of many drugs, infectious diseases and cancers.
Researchers have found evidence that one of our own proteins is a major source of mutations evident in most breast cancers.
A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated through strict control of gene activity. If the regulation is lost, specialized cells cannot develop correctly during development. In adulthood, the specialized cells may forget their identity and develop into cancer cells.
Devising a method for more precise and less invasive treatment of cancer tumors, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells.
Double-strand breaks in DNA happen every time a cell divides and replicates. Depending on the type of cell, that can be pretty often. Many proteins are involved in everyday DNA repair, but if they are mutated, the repair system breaks down and cancer can occur. Cells have two complicated ways to repair these breaks, which can affect the stability of the entire genome.
Researchers have developed a novel computer algorithm to quantify a major risk factor for breast cancer based on analysis of a screening mammogram. Increased levels of mammographic breast density have been shown in multiple studies to be correlated with elevated risk of breast cancer, but the approach to quantifying it has been limited to the laboratory setting. This new discovery opens the door for translation to the clinic.
A pair of University of Colorado Cancer Center studies published this month show that the milk thistle extract, silibinin, kills skin cells mutated by UVA radiation and protects against damage by UVB radiation—thus protecting against UV-induced skin cancer and photo-aging.
Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein present in several types of cancer, including breast and ovarian cancer, which could be helpful in preventing tumors from coming back.
Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease. In the latest example, scientists have developed an approach to mine the repetitive segments of DNA at the ends of chromosomes for insights into cancer.
A research team has discovered a molecular pathway that contributes to triple-negative breast cancer, an often deadly and treatment resistant form of cancer that tends to strike younger women. They also identified vitamin D and some protease inhibitors as possible new therapies and discovered a set of three biomarkers that can help to identify patients who could benefit from the treatment.
One of the most common types of brain tumors in adults, glioblastoma multiforme, is one of the most devastating. Even with recent advances in surgery, radiation and chemotherapy, the aggressive and invasive tumors become resistant to treatment, and median survival of patients is only about 15 months.
Epigenetics research has expanded rapidly over the last several years, as evidenced by the exponential increase in published literature in this field. Breakthroughs have been made in the elucidation of basic epigenetic mechanisms such as histone modification, and with these advances have come an understanding of the critical role epigenetic modifications play in the development and progression of cancer.
Following a three-year study using more than 2,800 mice, a University of Missouri researcher was not able to replicate a series of previous studies by another research group investigating the controversial chemical BPA. The MU study is not claiming that BPA is safe, but that the previous series of studies are not reproducible.
The spread of cancer cells may be slowed by targeting the protein km23-1. A motor protein that transports cargo within the cell, km23-1 is also involved in the movement or migration of cells. Migration is necessary for cancer to spread, so understanding this cell movement is important for development of better cancer treatments.