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'Stem Cell' Test Could Identify Most Aggressive Breast Cancers

March 5, 2015 10:03 am | by The Institute of Cancer Research | News | Comments

Testing breast cancer cells for how closely they resemble stem cells could identify women with the most aggressive disease, a new study suggests.                   

Mouse Study Finds Extra Oxygen May Spur Tumor-Fighting Cells

March 4, 2015 4:35 pm | by Lauran Neergaard, AP Medical Writer | News | Comments

A provocative study in mice suggests something as simple as breathing in extra oxygen might give immune cells a boost in attacking cancer.                    

Protein May Be Key to Cancer's Deadly Resurgences

March 3, 2015 4:29 pm | by Pete Farley, University of California San Francisco | News | Comments

Tumor recurrence following a period of remission is the main cause of death in cancer. The ability of cancer cells to remain dormant during and following therapy, only to be reactivated at a later time, frequently with greater aggressiveness, is one of the least-understood aspects of the disease.

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New Nanodevice Defeats Drug Resistance

March 3, 2015 10:33 am | by Anne Trafton, MIT | News | Comments

Tiny particles embedded in gel can turn off drug-resistance genes, then release cancer drugs.                            

Newly-Found T Memory Stem Cells May Be Key to Gene Therapy

February 27, 2015 10:41 am | by Cynthia Fox, Science Writer | Articles | Comments

Genetically engineered T memory stem cells (Tscm) can last more than 12 years in patients’ bodies, and can continually generate appropriate T cell armies for them, says an innovative study looking at two historic clinical trials.     

Unique Tags Identify Individual Yeast Families

February 26, 2015 10:05 am | by Krista Conger, Stanford School of Medicine | News | Comments

A technique developed by researchers has implications for understanding how cancer cells evolve as a tumor grows or how a virus spreads and changes during an infection.                  

Graphene Shows Potential as Novel Anti-Cancer Therapeutic Strategy

February 25, 2015 10:35 am | by University of Manchester | News | Comments

Scientists have used graphene to target and neutralize cancer stem cells while not harming other cells.                          

Previously Unknown Effect of Vitamin A Identified

February 24, 2015 12:42 pm | by Lund University | News | Comments

Researchers have identified a previously unknown effect of vitamin A in human embryonic development.                           

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Nano-Spies Force Tumors to Reveal Themselves

February 24, 2015 9:57 am | by Bruce Goldman, Stanford University | News | Comments

Investigators administered a customized genetic construct consisting of tiny rings of DNA, called DNA minicircles, to mice.                       

Study Shows Destroying Material That Cloaks Cancer Cells Could Benefit Patients

February 24, 2015 9:31 am | by Translational Genomics Research Institute | News | Comments

Like a stealth jet cloaks itself from radar, cancer cells cloak themselves within tumors by hiding behind a dense layer of cellular material known as stroma.                 

Camel, Alpaca Antibodies Target Anticancer Viruses Directly to Tumors

February 19, 2015 11:49 am | by Julia Evangelou Strait, WUSTL | News | Comments

Using antibodies from camels and alpacas, scientists have found a way to deliver anticancer viruses directly to tumor cells, leaving other types of cells uninfected.                

Keeping Atherosclerosis in Check with Novel Targeted Nanomedicines

February 19, 2015 11:42 am | by Columbia University | News | Comments

Nanometer-sized “drones” that deliver a special type of healing molecule to fat deposits in arteries could become a new way to prevent heart attacks caused by atherosclerosis.              

New Nanogel for Drug Delivery

February 19, 2015 11:31 am | by Anne Trafton, MIT | News | Comments

Scientists are interested in using gels to deliver drugs because they can be molded into specific shapes and designed to release their payload over a specified time period. However, current versions aren’t always practical because must be implanted surgically.

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Two Cell-Signaling Molecules Found to Suppress the Spread of Melanoma

February 17, 2015 10:21 am | by NYU Langone | News | Comments

Findings advance efforts to identify who would benefit from more aggressive therapy at earliest stages.                          

Taking Technology from the Lab to the Patient

February 17, 2015 10:06 am | by Anne Trafton, MIT | News | Comments

A MIT researcher wants to bring advances in drug delivery and biomaterials to the clinic.                            

Study Ties More Deaths, Types of Disease, to Smoking

February 12, 2015 2:06 pm | by Marilynn Marchione, Associated Press | News | Comments

Breast cancer, prostate cancer, and even routine infections. A new report ties these and other maladies to smoking and said an additional 60,000 to 120,000 deaths each year in the United States are probably due to tobacco use.      

Sequence of Genetic Mutations Determines How Cancer Behaves

February 12, 2015 10:15 am | News | Comments

Most of the genetic mutations that cause cancer result from environmental ‘damage’ (for example, through smoking or as a result of over-exposure to sunlight) or from spontaneous errors as cells divide. 

Plant Extract Fights Brain Tumor

February 10, 2015 5:06 pm | by Max Planck Society | News | Comments

Silibinin has an outstanding safety profile in humans and is currently used for the treatment of liver disease and poisoning.                                                     

Screening Tool Could Speed Ovarian Cancer Drug Development

February 10, 2015 4:56 pm | by University of Chicago | News | Comments

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

90 Percent Approve of Cancer Screening But Uptake is Lower

February 10, 2015 4:35 pm | by Cancer Research UK | News | Comments

The researchers, from Cancer Research UK's Health Behaviour Research Centre at University College London (UCL), interviewed almost 1,900 people aged 50-80 years old about their views on cancer screening.                   

Startup Uses Google Glass to Improve Patient-Physician Relationship

February 10, 2015 9:28 am | by Tracie White, Stanford Medical School | News | Comments

Firsthand experience working in hospitals and clinics helped inspire third-year Stanford medical student Pelu Tran to explore a potential career path in the world of high-tech startups.             

Tackling Cancer With a New Paradigm

February 5, 2015 2:33 pm | by Yale | News | Comments

In the 1980s, immunotherapy researcher Lieping Chen, M.D., Ph.D., embraced the career goal of curing one cancer. That lofty-seeming goal is beginning to look more modest today. Recent clinical trials have shown that one cancer after another is vulnerable to immune modulation therapy, a cancer-fighting strategy Chen pioneered that for years was considered marginal.

Nanoparticle Gene Therapy Treats Brain Cancer in Rats

February 4, 2015 10:01 am | by Johns Hopkins | News | Comments

Despite improvements in the past few decades with surgery, chemotherapy and radiation therapy, a predictably curative treatment for glioma does not yet exist. New insights into specific gene mutations that arise in this often deadly form of brain cancer have pointed to the potential of gene therapy, but it’s very difficult to effectively deliver toxic or missing genes to cancer cells in the brain.

Uncovering Genetic Trigger for Immune Response

February 3, 2015 1:06 pm | by Yale University | News | Comments

The thousands of mitochondrial DNA (mtDNA) molecules present in each cell are known primarily for their role converting food and oxygen into energy. But Yale researchers have identified an unexpected relationship between mtDNA and the innate immune response.

President Obama Reveals Details About Precision Medicine Project

February 1, 2015 6:45 pm | by Ryan Bushey, Associate Editor | Videos | Comments

President Obama held a press conference revealing new details surrounding the Precision Medicine initiative he announced during the State of The Union.                               

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