Physician-researchers have identified a vulnerability of certain lung cancer cells– a specific genetic weakness that can be exploited for new therapies.
Although bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn’t changed much in more than 70 years.
Researchers reported that three-dimensional scaffolds used to culture Ewing’s sarcoma cells were effective at mimicking the environment in which such tumors develop.
In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers have discovered a novel approach for treatment of tumors.
Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths. New research may bring scientists closer to designing cancer therapeutics that can target tumors with pinpoint accuracy.
An intuitive approach, which co-opts the body’s own molecular machinery, has led to massive expansions of umbilical cord blood cells. It and other new approaches “will revolutionize all transplantation,” says University of Minnesota Blood and Marrow Transplantation Director John Wagner.
In a laboratory study pairing food chemistry and cancer biology, scientists tested the potentially harmful effect of foods and flavorings on the DNA of cells. They found that liquid smoke flavoring, black and green teas and coffee activated the highest levels of a well-known, cancer-linked gene called p53.
Researchers have identified a humanized monoclonal antibody that targets and directly kills chronic lymphocytic leukemia (CLL) cells. The findings represent a potential new therapy for treating at least some patients with CLL, the most common type of blood cancer in the United States.
The first multi-gene test that can help predict cancer patients' responses to treatment using the latest DNA sequencing techniques has been launched in the NHS. The test detects mutations across 46 genes in cancer cells.
Zenalux Biomedical offers the Zenascope PC1, a biological tissue spectrometer that non-destructively measures biological tissue characteristics (biomarkers) that reflect underlying function and composition. The device is being used to detect the presence of cancer as well as other disease states and has also shown promise in monitoring therapy.
Inflammation is stirring up headlines again. Anti-inflammatory aspirin prevented thousands more cancers. The anti-inflammatory “miracle molecule” resveratrol came back. Psychologists report inflammation is stoked by even minor tensions. And archaeologists say all this knowledge is long overdue, as even Egyptian mummies have clogged arteries. We have been plagued by inflammation since the time of the Pharaohs.
Hormonal therapies can help control advanced prostate cancer for a time. However, for most men, at some point their prostate cancer eventually stops responding to further hormonal treatment. This stage of the disease is called androgen-insensitive or castration-resistant prostate cancer.
Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present. Now, a team of researchers has devised a molecular sensor that can detect levels of lactate in individual cells in real time.
Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find.
New research performed on lab-grown human skin suggests that short but powerful bursts of THz radiation may both cause DNA damage and increase the production of proteins that help the body fight cancer.
Researchers say they have found that stem cells from a patient’s own fat may have the potential to deliver new treatments directly into the brain after the surgical removal of a glioblastoma.
A seemingly obscure gene in the female fruit fly that is only active in cells that will become eggs has led researchers to the discovery of an atypical protein that lures, traps and inactivates the powerful Polo kinase, widely considered the master regulator of cell division.
Despite significant advances, cancer remains one of the predominant causes of mortality in the modern world, and as such has remained a top research priority. It is a complex and continually evolving genetic disease and, as such, requires sophisticated tools for study.
The Food and Drug Administration has approved a new imaging drug, Lymphoseek, from Navidea Biopharmaceuticals Inc., to help doctors locate lymph nodes in patients with breast cancer and skin cancer.
A new study shows that bitter melon juice restricts the ability of pancreatic cancer cells to metabolize glucose, thus cutting the cells’ energy source and eventually killing them.
A new immunoassay that tests for the presence of three biomarkers appears to be a valid screening method for the early detection of malignant kidney cancer, according to new data.
Some cellular proteins have multiple, and occasionally opposing, functions. Researchers demonstrated that the oncogenic protein SRSF1 can also trigger a stop in cell growth and prevent cancerous proliferation by stabilizing p53, the powerful tumor-suppressor protein.
Researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States.
The gene most strongly linked to obesity and overeating may also increase the risk of malignant melanoma– the most deadly skin cancer, new research reveals.