Inspired by a chemical that fungi secrete to defend their territory, chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.
A multi-institutional team has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common malignant brain tumor in children.
As cancer researchers are learning more about the causes of glioblastoma tumor cell growth and drug resistance, they are discovering molecular pathways that might lead to new, targeted therapies to potentially treat this deadly cancer.
Researchers developing innovative biological and chemical techniques to image and diagnose cancer, have recently been investigating the use of magnetic beads in cancer diagnosis.
In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells.
Researchers have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions.
New research argues that prolonged chemotherapy decreases the development of new brain cells and disrupts ongoing brain rhythms in the part of the brain responsible for making new memories.
A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study. The discovery might one day lead to better forms of treatment for patients with MS.
If a genome is the blueprint for life, then the chief architects are tiny slices of genetic material that orchestrate how we are assembled and function, researchers report.
A new study shows that resistant starch helps the body resist colorectal cancer through mechanisms including killing pre-cancerous cells and reducing inflammation that can otherwise promote cancer.
A team of researchers has shown that the concept of how the speed of creation affects performance also applies to how a protein they studied impacts circadian clock function.
Diagnostics maker Cepheid said Tuesday it will work with Oregon Health & Science University to develop tests that predict the risk of recurrence of breast and prostate cancer. Cepheid said it will work with OHSU's Knight Cancer Institute. The tests will run on the Cepheid GeneXpert system....
Reports that milk in the Balkans has been contaminated by a cancer-causing toxin have triggered a major health scare throughout the region, with authorities appealing for calm before official tests are conclusive. Senior agriculture official Goran Jesic claims on his website that out of 35 tested...
Shares of Pharmacyclics Inc. climbed to an all-time high Friday after the company said it expects to file for marketing approval of its cancer drug ibrutinib this year. If approved, it would be Pharmacyclics first drug for sale.
Scientists have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
Researchers have identified a family of human genes known as Tousled-like kinases (TLKs) that play a key role in the suppression and activation of Kaposi’s sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV).
Researchers have adapted natural mechanisms in living organisms to detect specific molecules, such as cocaine, more accurately and quickly. Their work may greatly facilitate the rapid screening of many drugs, infectious diseases and cancers.
New evidence suggests that an otherwise promising class of cancer drugs may actually increase the risk of tumors spreading to bone, according to researchers.
Researchers have found evidence that one of our own proteins is a major source of mutations evident in most breast cancers.
A lack of the protein endoglin in the blood vessels of tumour-bearing mice enables the spread of daughter tumours, according to researchers. Given that the tumour vasculature constitutes an important barrier to the spread of cancer cells, the team suggests that drugs should be developed to strengthen the blood vessels' protective function.
A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated through strict control of gene activity. If the regulation is lost, specialized cells cannot develop correctly during development. In adulthood, the specialized cells may forget their identity and develop into cancer cells.
Devising a method for more precise and less invasive treatment of cancer tumors, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells.
Double-strand breaks in DNA happen every time a cell divides and replicates. Depending on the type of cell, that can be pretty often. Many proteins are involved in everyday DNA repair, but if they are mutated, the repair system breaks down and cancer can occur. Cells have two complicated ways to repair these breaks, which can affect the stability of the entire genome.
Researchers have developed a novel computer algorithm to quantify a major risk factor for breast cancer based on analysis of a screening mammogram. Increased levels of mammographic breast density have been shown in multiple studies to be correlated with elevated risk of breast cancer, but the approach to quantifying it has been limited to the laboratory setting. This new discovery opens the door for translation to the clinic.
A pair of University of Colorado Cancer Center studies published this month show that the milk thistle extract, silibinin, kills skin cells mutated by UVA radiation and protects against damage by UVB radiation—thus protecting against UV-induced skin cancer and photo-aging.