Stop sunbathing and using indoor tanning beds, the acting U.S. surgeon general warned in a report released Tuesday that cites an alarming 200 percent jump in deadly melanoma cases since 1973.
When cancers spread into the bloodstream, they often take on different characteristics, requiring different therapies. But it is hard to find these rare blood-borne cells. So, relapsed patients often do not get personalized care. Now, researchers have come up with a solution that zeros in on elusive circulating tumor cells (CTCs).
Researchers have identified a mechanism that overrides the cells’ warning signals, enabling cancers to continue to divide even without a robust blood supply.
In a massive effort to catalog the molecular causes of stomach cancer, scientists have identified four subtypes of tumors based on shared mutations and other molecular abnormalities.
Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study by Tulane University School of Medicine cancer researchers.
The European Society for Medical Oncology (ESMO) has expressed concern that the proposed EU General Data Protection Regulation could make cancer research impossible and add a significant burden to both doctors and cancer patients.
Viruses designed to target and kill cancer cells could boost the effectiveness of chemotherapy to the arms and legs and help avoid amputation. Scientists tested the effectiveness of a genetically engineered version of the virus used to vaccinate against smallpox. They found use of the virus alongside isolated limb perfusion chemotherapy was more effective in rats than either treatment on its own.
In an analysis of metabolites used by the body to make fuel in normal and cancerous cells in human kidney tissue, a research team identified an enzyme that is key to applying the brakes on tumor growth.
Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world's deadliest cancers. By identifying the cause of this metastasis—which often happens quickly in lung cancer and results in a bleak survival rate—Salk scientists are able to explain why some tumors are more prone to spreading than others.
Researchers have uncovered a genetic vulnerability of cancer cells that express telomerase— an enzyme that drives their unchecked growth— and showed that telomerase-expressing cells depend upon a gene named p21 for their survival.
In recent years, aggressive research and substantial financial investments have been directed at discovering pre-symptomatic indicators of cancer, known as biomarkers. But as lead author researchers at Arizona State University’s Biodesign Institute emphasize in a new study, the quest for cancer biomarkers has been stymied by a number of factors. They describe a new technique for early disease detection, which they call immunosignaturing.
Scientists at the University of East Anglia have shown how the main psychoactive ingredient in cannabis could reduce tumor growth in cancer patients. Research reveals the existence of previously unknown signaling platforms which are responsible for the drug’s success in shrinking tumors. It is hoped that the findings could help develop a synthetic equivalent with anti-cancer properties.
Bowel cancer patients with high levels of vitamin D in their blood are more likely to survive the disease, a new study shows. Patients with the highest levels of vitamin D have half the risk of dying compared with those with the lowest levels, the findings reveal.
Researchers have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer. Knowledge of these genomic changes may expand the number of possible therapeutic targets for this disease and potentially identify a greater number of patients with treatable mutations because many potent cancer drugs that target these mutations already exist.
Mice exposed to low doses of arsenic in drinking water, similar to what some people might consume, developed lung cancer, researchers have found. Arsenic is present in the environment as a naturally occurring substance or due to contamination from human activity.
A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy. An international collaboration of researchers unlocked the secret behind the activation of the Ras family of proteins.
Insights into how cells move through the body could lead to innovative techniques to stop cancer cells from spreading and causing secondary tumors, according to new UCL research. Scientists discovered that cells can change into an invasive, liquid-like state to readily navigate the narrow channels in our body.
A few therapies derived from human medicine are available for dogs, but a very successful form of therapy by which antibodies inhibit tumor growth has not yet been available for animals. Now, scientists have developed, for the first time, antibodies to treat cancer in dogs.
An association between high blood cholesterol and breast cancer has been found in a study of more than 1 million patients over a 14-year time period in the UK.
Researchers completed a study that generated pseudogene expression profiles in 2,808 patient samples representing seven cancer types. The results indicated that the science of pseudogene expression analysis may very well play a key role in explaining how cancer occurs.
Scientists have shown that a member of the protein family known as SUMO (small ubiquitin-like modifier) is a key to why tumor cells multiply uncontrollably, especially in the case of glioblastoma.
A new study by radiation oncologists has found that proton beam therapy significantly improved disease free survival and tumor control when compared to IMRT in a variety of advanced head and neck cancers.
Researchers at the University of California, San Diego School of Medicine say a protein essential to regulating cell cycle progression – the process of cell division and replication – activates a key tumor suppressor, rather than inactivating it as previously thought.
A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, according to researchers.
Almost 40 percent of pancreatic cancers– one of the deadliest forms of cancer– could be avoided in the UK through maintaining a healthy weight and not smoking, according to new research.